Diffusion-Weighted Magnetic Resonance Imaging in Renal Lesion Characterization

Year 2012, Volume: 37 Issue: 1, 27 - 36, 01.03.2012

Elif Karadeli Gürcan Erbay Zafer Koç Bahattin Ulu

Abstract

Objective: To present the diffusion weighted magnetic resonance imaging findings of the patients with renal lesions and to explore ADC values of cystic and solid lesions. Materials and Methods: 20 patients with renal lesion (16 men, 4 women) were included in the study. All patients evaluated with diffusion weighted magnetic resonance imaging. 9 patients had renal cell carcinoma, one patient had oncocytoma and 10 patients had cyst. Results: Between all ADC values of lesions and ADC values of normal kidney parenchyma were significantly different. In addition, ADC values of malignant lesions were significantly lower than ADC values of normal kidney parenchyma and cyst. The lowest ADC value of malignant lesions was 0.75x 10-3 mm2 / s. The ADC values of malignant lesions varied between 0.75x 10-3 - 2.25x 10-3 mm2 / s values for ADC (b0, 111, 222, 333 s/mm2) . Whereas the lowest ADC value of cysts were calculated 2.81x 10-3 mm2 / s. All cysts had hyperintense signal on T2 weighted and diffusion-weighted images and high ADC values on ADC maps. Malignant lesions had low ADC values on ADC maps. Conclusion: The technique has the advantage that it is non-invasive without need for gadolinium administration, takes about 2 minute. This method provides qualitative and quantitative infomation on tissue characterization. DA-MRI and ADC values are important for characterization of renal lesions. Especially, utility of diffusion-weighted magnetic resonance imaging in the patients with risk for nephrogenic systemic fibrosis (NSF) could be beneficial.

Keywords

Magnetic resonance imaging, diffusion, , renal, lesion

Böbrek Lezyonlarının Karakterizasyonunda Difüzyon Ağırlıklı Manyetik Rezonans Görüntülemesi

Abstract

Amaç: Böbrek lezyonlarını difüzyon ağırlıklı Manyetik Rezonans Görüntüleme (DA-MRG) ile değerlendirmek ve kistik ve solid lezyonların ADC değerlerini ortaya koymaktır Gereç ve Yöntem: Böbrek lezyonu olan 20 hasta (16 erkek, 4 kadın) çalışmaya dahil edildi. Tüm hastalar (9 renal hücreli karsinom, 1 onkositom, 10 kist) difüzyon ağırlıklı manyetik rezonans görüntüleme ile değerlendirildi Bulgular: Normal böbrek parankiminin ADC değerleri ile lezyonların tüm ADC değerleri arasında istatistiksel olarak önemli fark vardı. Malign lezyonların ADC değerleri normal böbrek parankimi ve kistlerden önemli derecede düşük bulundu. Malign lezyonların en düşük ADC değerleri 0.75x 10-3 mm2 / s bulundu. ADC (b0, 111, 222, 333 s/mm2) için, malign lezyonların ortalama ADC değerleri 0.75x 10-3 - 2.25x 10-3 mm2/s arasında değişmekte olup, buna karşın kistlerin en düşük ADC değerleri 2.81x 10-3 mm2 / s bulundu. Tüm kistler T2 ağırlıklı sekanslarda, difüzyon ağırlıklı görüntülerde hiperintens sinyal ve ADC haritalarında yüksek ADC değerleri gösterirken, malign lezyonlarda düşük ADC değerleri bulundu. Sonuç: DA-MRG’nin avantajı yaklaşık 2 dakika süren, gadolinyum gereksinimi olmayan, noninvaziv bir teknik olmasıdır. Bu metod kalitatif ve kantitatif doku karakterizasyonu yapılmasına olanak sağlamaktadır. Böbrek lezyonlarının karakterizasyonunda difüzyon ağırlıklı görüntüleme ve ADC değerleri önemlidir. Özellikle nefrojenik sistemik fibrozis (NSF) riski olan hastalarda DA-MRG kullanımı yararlı olabilir.

Keywords

Manyetik rezonans görüntüleme, difüzyon, renal, lezyon

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