Mucormycosis with Orbital Apex Syndrome in a Renal Transplant Recipient

Year 2015, Volume: 40 Issue: 2, 384 - 389, 29.09.2015

Ebru Kurşun Tuba Turunc Yusuf Demiroğlu Hakan Yabanoğlu Şenay Demir Kenan Çalışkan Gökhan Moray Hande Arslan Mehmet Haberal

https://doi.org/10.17826/cutf.08073

Abstract

Mucormycosis is a rarely encountered invasive fungal infection with high mortality.Solid organ transplantation is one of the risk factors for mucormycosis. Mucormycosis can be classified in six different groups according to the anatomical localization; rhinocerebral, pulmonary, cutaneous, gastrointestinal, disseminated, and other less common involvements. This paper presented a mucormycosis case with rhinoorbitocerebral involvementin a renal transplantation receiver, which manifested with orbital apex syndrome.

Keywords

Mucormycosis, orbital apex syndrome, solid organ transplantation

Bir Böbrek Transplantasyon Alıcısında Orbital Apeks Sendromu ile Seyreden Mukormikoz

Abstract

Mukormikozis nadir görülen mortalitesi yüksek invaziv bir mantar enfeksiyonudur. Solid organ transplantasyonu mukormikoz için risk faktörlerinden birisidir. Mukormikoz anatomik yerleşim yerleri temel alındığında; rinoserebral, pulmoner, kutanöz, gastrointestinal, dissemine ve sık rastlanılmayan diğer tutulumlar olmak üzere altı farklı grup olarak sınıflandırılabilmektedir. Bu yazıda böbrek transplantasyonu alıcısında orbital apeks sendromu ile prezente olan rinoorbito-serebral tutulumu olan mukormikoz olgusu sunulmuştur.

Keywords

Mukormikoz, orbital apeks sendromu, solid organ transplantasyonu

References

• 1. A Turan MN, Tatar E, Yaprak M, Arda B, Kitiş Ö, Metin DY et al. A mucormycosis case presented with orbital apex syndrome and hemiplegia in a renal transplant patient. Int Urol Nephrol. 2012.
• 2. Demiroglu YZ, Turunc T, Erkan NB, Alkan Ö, Alıskan HE, Colakoglu S et al. Rhinocerebral Mucormycosis Treated with Posaconazole: A Case Report. Klimik Dergisi. 2010;23:130-3.
• 3. Sun HY, Singh N. Mucormycosis: its contemporary face and management strategies. Lancet Infect Dis. 2011;11:301-11.
• 4. Chkhotua A, Yussim A, Tovar A, Weinberger M, Sobolev V, Bar-Nathan N et al. Mucormycosis of the renal allograft: case report and review of the literature. Transpl Int. 2001;14:438-41.
• 5. Nampoory MR, Khan ZU, Johny KV, Constandi JN, Gupta RK, Al-Muzairi I et al. Invasive fungal infections in renal transplant recipients. J Infect. 1996;33:95-101.
• 6. Brown J. Zygomycosis: an emerging fungal infection. Am J Health Syst Pharm. 2005;62:2593-6.
• 7. Wali U, Balkhair A, Al-Mujaini A. Cerebro-rhino orbital mucormycosis: an update. J Infect Public Health. 2012;5:116-26.
• 8. Koc Z, Koc F, Yerdelen D, Ozdogu H. Rhino-orbitalcerebral mucormycosis with different cerebral involvements: infarct, hemorrhage, and ophthalmoplegia.Int J Neurosci. 2007;117:1677-90.
• 9. Spellberg B, Kontoyiannis DP, Fredricks D, Morris MI, Perfect JR, Chin-Hong PV et al. Risk factors for mortality in patients with mucormycosis. Med Mycol. 2012;50:611-8.
• 10. Yeh S, Foroozan R. Orbital apex syndrome. Curr Opin Ophthalmol. 2004;15:490-8.