Adipose-Derived Stem Cells and Application Areas

Year 2015, Volume: 40 Issue: 3, 399 - 408, 30.09.2015

Müjde Kıvanç Şamil Öztürk , Sevtap Gökalp İlhan Özdemir İbrahim Tuğlu

https://doi.org/10.17826/cutf.44976

Cited By: 1

Abstract

The use of stem cells derived from adipose tissue as an autologous and self-replenishing source for a variety of differentiated cell phenotypes, provides a great deal of promise for reconstructive surgery. The secret of the human body, stem cells are reserved. Stem cells are undifferentiated cells found in the human body placed in any body tissue characteristics that differentiate and win ever known to cross the tissue instead of more than 200 diseases and thus improve and, rejuvenates the tissues. So far, the cord blood of newborn babies are used as a source of stem cells, bone marrow, and twenty years after tooth stem cells in human adipose tissue, scientists studied more than other sources of stem cells in adipose tissue and discovered that. Increase in number of in vitro studies on adult stem cells, depending on many variables is that the stem cells directly to the desired soybean optimization can be performed.. We will conclude by assessing potential avenues for developing this incredibly promising field. The aim of this paper is to review the existing literature on applications of harvest, purification, characterization and cryopreservation of adipose-derived stem cells (ASCs).

Keywords

Stem cell, Adipose tissue, Wound Healing, Differentiation

Adipoz Kaynaklı Kök Hücreler ve Uygulama Alanları

Abstract

Kompleks bir canlı olan insan, olağanüstü bir koruma mekanizması geliştirerek zararlı olabilecek etkenlerden mümkün olduğunca kendini uzak tutar ve bunu başarabilmek için de bazı farklılaşmamış hücreleri kullanır. Yani her türlü doku kayıplarında yeniden fonksiyon gösterebilmesinin sırrı sahip olduğu kök hücrelerde saklıdır. Vücudumuzda farklılaşmamış bir hücre olarak bulunan kök hücreler herhangi bir organa yerleştirildiklerinde farklılaşıp o dokunun özelliklerini kazanarak şimdiye kadar bilinen oldukça fazla dokunun yerine geçebilmekte ve bu sayede hastalıkları iyileştirip, dokuları yenileyebilmektedir. Kök hücre kaynağı olarak kullanılan, kordon kanı, kemik iliği ve yirmi yaş dişinden sonra bilim adamları insan yağ dokusunda da kök hücre araştırdılar ve yağ dokusunda diğer kaynaklardan çok daha fazla kök hücre bulunduğunu keşfettiler. Bu hücreler üzerinde yapılan in vitro çalışmalar şunu gösteriyor ki bu hücrelerden birçok değişkene bağlı istenen soya yönelik doğrudan kök hücre optimizasyonu yapılabilmektedir. Bu derlemede de, adipoz kaynaklı kök hücrelerin saflaştırılması ve uygulamalarda kullanılması ile ilgili mevcut literatür gözden geçirilerek bilim dünyasına katı sağlaması amaçlanmıştır.

Keywords

Kök hücre, Yağ dokusu, Yara tamiri, Farklılaşma

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