Idiopathic Childhood Occipital Lobe Epilepsies in Turkish Children

Year 2015, Volume: 40 Issue: 3, 504 - 509, 30.09.2015

Faruk İncecik , Özlem M. Hergüner Gülen Mert Şakir Altunbaşak

https://doi.org/10.17826/cutf.50852

Cited By: 1

Abstract

Purpose: Two forms of idiopathic occipital lobe epilepsy can be distinguished: an early onset or Panayiotopoulos type (PS), and a late onset or Gastaut type (GS). The aim of this study was to identify clinical manifestations and outcome in Turkish children with idiopathic occipital lobe epilepsy. Material and Methods: Thirty nine children (27 boys, 12 girls) were divided into the PS and GS type, according to the classification for epileptic seizures of the International League Against Epilepsy. Results: Among the 39 patients, 27 (69.3%) were boys and 12 (30.7%) were girls and the mean age at the seizure onset was 77.38 ± 27.33 months (36-145 months). The PS type patients consisted of 27 children (19 boys, 8 girls). The average age of seizure onset in PS type patients was 60.76 ± 14.21 months (range, 36-94 months). The GS type patients consisted of 12 children (8 boys, 4 girls), and seizure onset was 107.7 ± 18.8 months (range, 72-145 months). Ictal vomiting was more common in the PS type patients, and visual symptoms were more common in the GS type patients. We detected that after treatment, 27 patients (100%) in PS type and 10 patients (83.3%) in GS type became seizures-free. Two patients continued having seizures in GS type. Conclusions: The average age of seizure onset was much younger in the PS than in the GS. Also, in idiopathic occipital lobe epilepsy, the PS type has better seizure-free and prognosis than the GS.

Keywords

Idiopathic childhood occipital epilepsies, clinical findings, children

Türk Çocuklarında İdiopatik Çocukluk Çağı Oksipital Lob Epilepsisi

Abstract

Amaç: İdiopatik çocukluk çağı oksipital lob epilepsisinin iki farklı tipi tanımlanmıştır: erken başlangıçlı veya Panayiotopoulos tip (PS) ve geç başlangıçlı Gastaut tip (GS). Bu çalışmanın amacı, idiopatik çocukluk çağı oksipital lop epilepsisi tanısı alan Türk çocuklarında klinik bulguları ve seyri ortaya koymaktır. Materyal ve Metod: Otuz dokuz çocuk (27 erkek, 12 kız), Uluslarası Epilepsi ile Savaş Derneği (İLAE) tarafından önerilen epileptik nöbet sınıflamasına göre PS ve GS tip olarak ayrıldı. Bulgular: Otuz dokuz hastanın, 27’si (69.3%) erkek ve 12’si (30.7%) kız idi ve ortalama nöbet başlangıç yaşı 77.38 ± 27.33 ay (36-145 ay) idi. Hastaların 27’si (19 erkek, 8 kız) PS tip idi. PS tip hastaların ortalama nöbet başlangıç yaşları 60.76 ± 14.21 ay (36-94 ay) idi. GS tip 12 hastanın (8 erkek, 4 kız) idi ve nöbet başlangıç yaşı 107.7 ± 18.8 ay (72-145 ay) idi. PS tip hastalarda iktal kusma ve GS tip hastalarda vizüel semptomlar daha sıktı. Tedavi sonrası PS tip hastaların 27’si (100%), GS tip hastaların 10’u (83.3%) nöbetsiz duruma gelmişti. GS tip hastalardan ikisinin nöbetleri devam ediyordu. Sonuç: Nöbet başlangıç yaşı ortalaması PS tipte, GS tipe göre daha erkendir. Ayrıca idiopatik çocukluk çağı oksipital lop epilepsisi olan, PS tipinin prognozu ve nöbetsizlik durumu, GS tipine göre daha iyidir.

Keywords

İdiopatik çocukluk çağı oksipital lob epilepsisi, klinik bulgular, çocuklar

References

• Gastaut H. A new type of epilepsy: benign partial epilepsy of childhood with occipital spike-waves. Clin Electroencephalogr. 1982;13:13-22.
• Engel J. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology. Epilepsia. 2001;42:796-803.
• Panayiotopoulos C. P. Benign childhood epilepsy with occipital paroxysms: a 15-year prospective study Ann Neurol. 1989;26:51-6.
• Panayiotopoulos C. P. Benign childhood epileptic syndromes with occipital spikes: new classification proposed by the International League Against Epilepsy. J Child Neurol. 2000;15:548-52.
• Covanis A. Panayiotopoulos syndrome: a benign childhood autonomic epilepsy frequently imitating encephalitis, syncope, migraine, sleep disorder, or gastroenteritis. Pediatrics. 2006;118:1237-43.
• Covanis A, Ferrie CD, Koutroumanidis M, Oguni H, Panayiotopoulos CP. Panayiotopoulos syndrome and Gastaut type idiopathic childhood occipital epilepsy. In: Roger J, Bureau M, Dravet C, Genton P, Tassinari CA, Wolf P, (eds). Epileptic Syndromes in Infancy, Childhood and Adolescence: Montrouge, France: John Libbey Eurotext. 2005;227-53.
• Gökçay A, Gökçay F, Ekmekçí O, Ulkü A. Occipital
• epilepsies in children. Eur J Paediatr Neurol. 2002;6:261-8.
• Du JC, Chien YH, Weng WC, Shen YZ, Lee WT. Clinical analysis of childhood occipital lobe epilepsy in 2007;36:387-92. Pediatr Neurol.
• Kivity S, Ephraim T, Weitz R, Tamir A. Childhood epilepsy with occipital paroxysms: clinical variants in 134 patients. Epilepsia. 2000;41:1522-33.
• Ferrie C, Caraballo R, Covanis A, Demirbilek V, Dervent A, Kivity S, et al. Panayiotopoulos syndrome: a consensus view. Dev Med Child Neurol. 2006;48:236-40.
• Panayiotopoulos CP. Vomiting as an ictal manifestation of epileptic seizures and syndromes. J Neurol Neurosurg Psychiatr. 1988;51:1448-51. 12. Caraballo R, Cersósimo R, Fejerman N. Panayiotopoulos syndrome: a prospective study of 192 patients. Epilepsia. 2007;48:1054-61.
• Adcock JE, Panayiotopoulos CP. Occipital lobe seizures and epilepsies. J Clin Neurophysiol. 2012;29:397-407.
• Oguni H, Hayashi K, Imai K, Muto K, Osawa M. Study on the early-onset variant of benign childhood epilepsy described as early-onset benign occipital seizure susceptibility syndrome. Epilepsia. 1999;40:1020-30.
• Wakamoto H, Nagao H, Fukuda M, et al. Idiopathic childhood occipital epilepsy of Gastaut: report of 12 patients. Pediatr Neurol. 2011;44:183-6.
• Lada C, Skiadas K, Theodorou V, Loli N, Covanis A. A study of 43 patients with panayiotopoulos syndrome, a common and benign childhood seizure susceptibility. Epilepsia. 2003;44:81-8.