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A Rare Cause of Diagnostic Delay: Primary Bone Lymphoma

Year 2015, Volume: 40 Number: Supplement 1, 8 - 11, 08.10.2015
https://doi.org/10.17826/cutf.51215

Abstract

Primary lymphomas of bone in childhood are not frequently diagnosed. Because of its rarity and little information about the issue, diagnostic delays can ocur in patients who present with complaints related with skeletal system. In this report, a 7-year-old female with bone lymphoma was presented, who initially diagnosed as osteomyelitis and could be diagnosed after 11-month-delay during an investigation of abdominal pain, probably originated from enlarged and conglomerated lymph nodes caused by tumoral infiltration. Clinicians must be aware of symptoms involving skeletal system, such as pain and swelling and malignant neoplasms should be considered in differential diagnosis.

References

  • Gebhardt MC. Bone tumors in children. Differential characteristics and treatment. Postgrad Med. 1984;76:87-96.
  • Kreutz J, Khamis J, Bauduin E, Francotte N, Khuc T. Primary bone lymphoma in a 10-year-old boy. JBR- BTR. 2013;96:381-2.
  • Bakhshi S, Singh P, Thulkar S. Bone involvement in pediatric non-Hodgkin's lymphomas.Hematology. 2008;13:348-51.
  • Suryanarayan K, Shuster JJ, Donaldson SS, Hutchison RE, Murphy SB, Link MP. Treatment of localized primary non-Hodgkin's lymphoma of bone in children: a Pediatric Oncology Group study. J Clin Oncol. 1999;17:456-9.
  • Furman WL, Fitch S, Hustu HO, Callihan T, Murphy SB. Primary lymphoma of bone in children. J Clin Oncol. 1989;7:1275-80.
  • Kitsoulis P, Vlychou M, Papoudou-Bai A, Karatzias G, Charchanti A, Agnantis NJ, Bai M. Primary lymphomas of bone. Anticancer Res. 2006;26:325- 37.
  • Senac MO Jr, Isaacs H, Gwinn JL. Primary lesions of bone in the 1st decade of life: retrospective survey of biopsy results. Radiology. 1986;160:491-5.
  • Miller SL, Hoffer FA. Malignant and benign bone tumors. Radiol Clin North Am. 2001;39:673-99.
  • Teo WY, Chan MY, Ng KC, Tan AM. Bony presentations of childhood haematological malignancy to the emergency room. J Paediatr Child Health. 2012;48:311-6.

Tanısal Gecikmenin Nadir Bir Nedeni: Primer Kemik Lenfoması

Year 2015, Volume: 40 Number: Supplement 1, 8 - 11, 08.10.2015
https://doi.org/10.17826/cutf.51215

Abstract

Primer kemik lenfomaları çocukluk çağında nadir görülen tümörlerdendir. Az görülmesi ve konu hakkında bilgi birikiminin yeterli olmayışı nedeniyle iskelet sistemi ile ilgili şikayetlerle başvuran hastalarda tanısal gecikmeler olabilmektedir. Bu yazıda başlangıçta osteosarkom tanısı alan ve 11 aylık gecikme sonrasında, muhtemelen tümör infiltrasyonuna bağlı büyümüş ve konglomere olmuş lenf nodlarının neden olduğu, karın ağrısı nedeniyle araştırılırken kemik lenfoması tanısı alan 7 yaşında bir kız hasta sunulmuştur. Klinisyenlerin, ağrı ve şişlik gibi iskelet sistemiyle ilgili semptomları dikkate alması ve malign tümörlerin de ayırıcı tanıda düşünülmesi gerekmektedir.

References

  • Gebhardt MC. Bone tumors in children. Differential characteristics and treatment. Postgrad Med. 1984;76:87-96.
  • Kreutz J, Khamis J, Bauduin E, Francotte N, Khuc T. Primary bone lymphoma in a 10-year-old boy. JBR- BTR. 2013;96:381-2.
  • Bakhshi S, Singh P, Thulkar S. Bone involvement in pediatric non-Hodgkin's lymphomas.Hematology. 2008;13:348-51.
  • Suryanarayan K, Shuster JJ, Donaldson SS, Hutchison RE, Murphy SB, Link MP. Treatment of localized primary non-Hodgkin's lymphoma of bone in children: a Pediatric Oncology Group study. J Clin Oncol. 1999;17:456-9.
  • Furman WL, Fitch S, Hustu HO, Callihan T, Murphy SB. Primary lymphoma of bone in children. J Clin Oncol. 1989;7:1275-80.
  • Kitsoulis P, Vlychou M, Papoudou-Bai A, Karatzias G, Charchanti A, Agnantis NJ, Bai M. Primary lymphomas of bone. Anticancer Res. 2006;26:325- 37.
  • Senac MO Jr, Isaacs H, Gwinn JL. Primary lesions of bone in the 1st decade of life: retrospective survey of biopsy results. Radiology. 1986;160:491-5.
  • Miller SL, Hoffer FA. Malignant and benign bone tumors. Radiol Clin North Am. 2001;39:673-99.
  • Teo WY, Chan MY, Ng KC, Tan AM. Bony presentations of childhood haematological malignancy to the emergency room. J Paediatr Child Health. 2012;48:311-6.
There are 9 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Serhan Küpeli

Publication Date October 8, 2015
Published in Issue Year 2015 Volume: 40 Number: Supplement 1

Cite

MLA Küpeli, Serhan. “A Rare Cause of Diagnostic Delay: Primary Bone Lymphoma”. Cukurova Medical Journal, vol. 40, 2015, pp. 8-11, doi:10.17826/cutf.51215.