Case Report
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Coexistence of uterine lipoma, leiomyoma and endometrial polyp

Year 2019, Volume: 44 Issue: 3, 1139 - 1141, 30.09.2019
https://doi.org/10.17826/cumj.500359

Abstract

Lipomas of the uterus are very rare tumors, they are often misdiagnosed by preoperative radiological examination due to their content and their rarity. Although MRI is preferred because of the fat nature of the lesion, the definitive diagnosis requires histopathological examination. Although many theories have been proposed about the histogenesis of the tumor, there is still no accepted theory. These lesions may have concomitant malignancy in the uterus, ovaries, and fallopian tubes, or may have other metabolic disorders and abnormal estrogen status. Here, we report a 39-year-old female patient who was admitted to the hospital with pelvic pain and irregular vaginal bleeding. Abdominal hysterectomy and bilateral salpingo-oopherectomy was performed and histopathological examination revealed rare occurrence of coexistent uterine lipoma, leiomyoma and endometrial polyp.

References

  • 1. Kitajima K, Kaji Y, Imanaka K, Sugihara R, Sugimura K.MRI findings of uterine lipoleiomyoma correlated with pathologic findings. AJR Am J Roentgenol.2007;189:W100-4
  • 2. Loffroy R, Nezzal N, Mejean N, Sagot P, Krausé D. Lipoleiomyoma of the uterus: Imaging features. Gynecol Obstet Invest. 2008;66:73–5.
  • 3. Avritscher R, Iyer RB, Ro J, Whitman G. Lipoleiomyoma of the uterus. AJR Am J Roentgenol. 2001;177:856.
  • 4. Aung T, Goto M, Nomoto M, Kitajima S, Douchi T, Yoshinaga M, et al. Uterine lipoleiomyoma: A histopathological review of 17 cases. Pathol Int. 2004;54:751–8.
  • 5. Akyildiz EU, Ozuysal S, Arici A, Atalay MA. Pure uterine lipoma, a very rare benign tumour. Korean J Pathol. 2010;44:679–81.
  • 6. Vamseedhar A, Shivalingappa DB, Suresh DR, Geetha RL. Primary pure uterine lipoma: A rare case report with review of literature. Indian J Cancer. 2011;48:385–7.
  • 7. Fujimoto Y, Kasai K, Furuya M, Honda N, Tojo R, Saito S, et al. Pure uterine lipoma. J Obstet Gynaecol Res. 2006;32:520–3.
  • 8. Bandopadhyay A, Ray S, Bera P, Gangopadhyay M, Chakrabarti I, Dey B, et al. Calcified pure uterine lipoma mimicking myoma. J Turk Ger Gynecol Assoc. 2010;11:113–4.
  • 9. Mignogna C, Di Spiezio Sardo A, Spinelli M, Sassone C, Cervasio M, Guida M, et al. A case of pure uterine lipoma: Immunohistochemical and ultrastructural focus. Arch Gynecol Obstet. 2009;280:1071–4
  • 10. Resta L, Maiorano E, Piscitelli D, Botticella MA. Lipomatous tumorsb of the uterus: clinico-pathological features of 10 cases with immunocytochemical study of histogenesis. Pathol Res Pract 1994; 190: 378-83
  • 11. Kumar S, Garg S, Rana P, Hasija S, Kataria SP, Sen R. Lipoleiomyoma of uterus: Uncommon incidental finding. Gynecol Obstet. 2013;3:145.
  • 12. Narchal S, Patil SB, Purohit PV, More SS. Lipoleiomyoma of uterus: A case report with review of literature. Int J Health Allied Sci. 2013;2:209–11.
  • 13. Chu CY, Tang YK, Chan TS, Wan YH, Fung KH. Diagnostic challenge of lipomatous uterine tumors in three patients. World J Radiol. 2012;4:58–62.
  • 14. Krenning RA, De Goey WB. Uterine lipomas: review of the literature Clin Exp Obstet Gynecol 1983; 10: 91-4
  • 15. Lau LU, Thoeni RF. Case report. Uterine lipoma: advantage of MRI over ultrasound. Br J Radiol 2005; 78: 72-4.
  • 16. Coumbaras M, Validire P, Strauss C, Herry M, Dahan H, Palau R. Uterine lipoma: MRI features with pathologic correlation. Abdom Imaging 2005; 30: 239-41
  • 17. Uterine Lipoleiomyoma and Lipoma: A Rare Unique Case Report with Review of Literature. Shirish S Chandawale, Kunjal Mukesh Karia, Neekita S Agrawal, Amardeep A Patil, Abhinav B Shetty, and Manpreet Kaur
  • 18. Salman MC, Atak Z, Usubutun A, Yuce K. Lipoleiomyoma of broad ligament mimicking ovarian cancer in a postmenopausal patient: Case report and literature review. J Gynecol Oncol. 2010;21:62–4
  • 19. Wang X, Kumar D, Seidman JD. Uterine lipoleiomyomas: A clinicopathologic study of 50 cases. Int J Gynecol Pathol. 2006;25:239–42.

Uterin lipoma, leiyomyoma ve endometrial polip birlikteliği

Year 2019, Volume: 44 Issue: 3, 1139 - 1141, 30.09.2019
https://doi.org/10.17826/cumj.500359

Abstract

Uterusun lipomları çok nadir görülen tümörler olup, preoperatif radyolojik incelemeleri ile içerikleri ve nadirlikleri nedeniyle sıklıkla yanlış tanı alırlar. Her ne kadar MRG lezyonun yağ yapısından dolayı tercih edilse de kesin tanı histopatolojik inceleme gerektirir. Tümörün histogenezi hakkında birçok teori öne sürülmüş olsa da, hala kabul edilmiş bir teori yoktur. Bu lezyonlar rahim, yumurtalıklar ve fallop tüplerinde eşlik eden maligniteye sahip olabilir veya başka metabolik bozukluklara ve anormal östrojen durumuna sahip olabilir. Burada, pelvik ağrı ve düzensiz vajinal kanama ile hastaneye başvuran 39 yaşında bir kadın hastayı sunuyoruz. Abdominal histerektomi ve bilateral salpingo-ooferektomi yapılmış ve histopatolojik incelemede nadir görülen uterin lipom, leiomyom ve endometrial polip birlikteliği saptanmıştır.

References

  • 1. Kitajima K, Kaji Y, Imanaka K, Sugihara R, Sugimura K.MRI findings of uterine lipoleiomyoma correlated with pathologic findings. AJR Am J Roentgenol.2007;189:W100-4
  • 2. Loffroy R, Nezzal N, Mejean N, Sagot P, Krausé D. Lipoleiomyoma of the uterus: Imaging features. Gynecol Obstet Invest. 2008;66:73–5.
  • 3. Avritscher R, Iyer RB, Ro J, Whitman G. Lipoleiomyoma of the uterus. AJR Am J Roentgenol. 2001;177:856.
  • 4. Aung T, Goto M, Nomoto M, Kitajima S, Douchi T, Yoshinaga M, et al. Uterine lipoleiomyoma: A histopathological review of 17 cases. Pathol Int. 2004;54:751–8.
  • 5. Akyildiz EU, Ozuysal S, Arici A, Atalay MA. Pure uterine lipoma, a very rare benign tumour. Korean J Pathol. 2010;44:679–81.
  • 6. Vamseedhar A, Shivalingappa DB, Suresh DR, Geetha RL. Primary pure uterine lipoma: A rare case report with review of literature. Indian J Cancer. 2011;48:385–7.
  • 7. Fujimoto Y, Kasai K, Furuya M, Honda N, Tojo R, Saito S, et al. Pure uterine lipoma. J Obstet Gynaecol Res. 2006;32:520–3.
  • 8. Bandopadhyay A, Ray S, Bera P, Gangopadhyay M, Chakrabarti I, Dey B, et al. Calcified pure uterine lipoma mimicking myoma. J Turk Ger Gynecol Assoc. 2010;11:113–4.
  • 9. Mignogna C, Di Spiezio Sardo A, Spinelli M, Sassone C, Cervasio M, Guida M, et al. A case of pure uterine lipoma: Immunohistochemical and ultrastructural focus. Arch Gynecol Obstet. 2009;280:1071–4
  • 10. Resta L, Maiorano E, Piscitelli D, Botticella MA. Lipomatous tumorsb of the uterus: clinico-pathological features of 10 cases with immunocytochemical study of histogenesis. Pathol Res Pract 1994; 190: 378-83
  • 11. Kumar S, Garg S, Rana P, Hasija S, Kataria SP, Sen R. Lipoleiomyoma of uterus: Uncommon incidental finding. Gynecol Obstet. 2013;3:145.
  • 12. Narchal S, Patil SB, Purohit PV, More SS. Lipoleiomyoma of uterus: A case report with review of literature. Int J Health Allied Sci. 2013;2:209–11.
  • 13. Chu CY, Tang YK, Chan TS, Wan YH, Fung KH. Diagnostic challenge of lipomatous uterine tumors in three patients. World J Radiol. 2012;4:58–62.
  • 14. Krenning RA, De Goey WB. Uterine lipomas: review of the literature Clin Exp Obstet Gynecol 1983; 10: 91-4
  • 15. Lau LU, Thoeni RF. Case report. Uterine lipoma: advantage of MRI over ultrasound. Br J Radiol 2005; 78: 72-4.
  • 16. Coumbaras M, Validire P, Strauss C, Herry M, Dahan H, Palau R. Uterine lipoma: MRI features with pathologic correlation. Abdom Imaging 2005; 30: 239-41
  • 17. Uterine Lipoleiomyoma and Lipoma: A Rare Unique Case Report with Review of Literature. Shirish S Chandawale, Kunjal Mukesh Karia, Neekita S Agrawal, Amardeep A Patil, Abhinav B Shetty, and Manpreet Kaur
  • 18. Salman MC, Atak Z, Usubutun A, Yuce K. Lipoleiomyoma of broad ligament mimicking ovarian cancer in a postmenopausal patient: Case report and literature review. J Gynecol Oncol. 2010;21:62–4
  • 19. Wang X, Kumar D, Seidman JD. Uterine lipoleiomyomas: A clinicopathologic study of 50 cases. Int J Gynecol Pathol. 2006;25:239–42.
There are 19 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Nilgün Söğütçü 0000-0002-2455-2964

Nazlı Sena Şeker 0000-0003-4588-7250

Publication Date September 30, 2019
Acceptance Date February 1, 2019
Published in Issue Year 2019 Volume: 44 Issue: 3

Cite

MLA Söğütçü, Nilgün and Nazlı Sena Şeker. “Coexistence of Uterine Lipoma, Leiomyoma and Endometrial Polyp”. Cukurova Medical Journal, vol. 44, no. 3, 2019, pp. 1139-41, doi:10.17826/cumj.500359.