Stresin cerrahi olmayan periodontal tedavi üzerine etkisi

Year 2020, Volume: 45 Issue: 3, 1182 - 1190, 30.09.2020

Mustafa Özcan Gönen Özcan

https://doi.org/10.17826/cumj.745326

Cited By: 1

Abstract

Amaç: Bu çalışmanın amacı stresin cerrahi olmayan periodontal tedavi (COPT) sonuçları üzerine etkisini değerlendirmektir.

Yöntem: Çalışmaya 40 yetişkin kronik periodontitis hastası dahil edildi. Klinik periodontal parametreler kaydedildi ve diş eti oluğu sıvısı (DOS) inflamatuar biyobelirteçleri (IL-1 beta, IL-6 ve IL-10) ve tükürük stres biyobelirteçleri (kromogranin-A, kortizol ve a-amilaz) toplandı. Hastaların stres derecesi ölçülerek kategorize edildi. Tüm klinik ve biyolojik parametreler COPT'den önce ve sonra 1. ayda kaydedildi.

Bulgular: Stresli hasta grubunda, klinik parametreler ve tükürük stres belirteç düzeyleri yüksek bulundu (p <0.05). İki grup arasında inflamatuar belirteçlerden IL-1 beta düzeylerinde istatistiksel olarak anlamlı bir fark tespit edildi (p <0.001). Tedavi sonrası klinik parametreler ve IL-1 beta düzeylerindeki değişim stressiz hastalarda anlamlı derece yüksek olarak tespit edildi (p <0.05).

Sonuç: Psikososyal stresin, kronik periodontitis hastalarında cerrahi olmayan periodontal tedaviye verilen yanıtı olumsuz etkilediği tespit edilmiştir. Periodontal hastalığa sahip bireylere psikoloijik destek sağlanarak yeni tedavi protokolleri oluşturulabilir.

Keywords

stres, biyobelirteç, inflamasyon, cerrahi olmayan periodontal tedavi

Supporting Institution

Gazi Üniversitesi Bilimsel Araştırma Projeleri Birimi

Project Number

03/2012-16

Effects of psychosocial stress on non-surgical periodontal treatment

Abstract

Purpose: The aim of this study was to evaluate the effects of psychocial stress on the outcome of non-surgical periodontal treatment (NPT).
Materials and Methods: Forty participants with chronic periodontitis were treated. Clinical parameters were recorded and inflammatory markers (IL-1b, IL-6 and IL-10) were analyzed from gingival crevicular fluid. Stress markers (chromogranin-A, cortisol, a-amylase) were measured from saliva. The patients were categorized as ‘stressed’ or ‘unstressed according to their stress status. All clinical and biological parameters were recorded before and at 1-month after NPT.
Results: All the clinical parameters and salivary stress marker levels were significantly higher in the stressed group. Among the inflammatory markers, only IL-1 level was significantly different between groups. The effects of stress was statistically significant for the clinical and biological parameters, with poorer response to treatment in the stressed group.
Conclusion: Patients under psychosocial stress had a poorer outcome following non-surgical periodontal treatment. New treatment protocols can be created by providing psychological support to individuals with periodontal disease. 

Keywords

stress, biomarkers, Nonsurgical Periodontal Debridement, Inflammation

Project Number

03/2012-16

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