Evaluation of gynecological complaints of women having inflammatory changes in their cervicovaginal smears

Year 2021, Volume: 46 Issue: 1, 81 - 87, 31.03.2021

Hanife Guler Donmez M.sinan Beksac

Abstract

Purpose: Inflammatory Pap-test is reported commonly, however, there is no consensus on its clinical significance. This study was to investigate the presence of gynecological complaints such as vaginal discharge, pruritus, burning, odor, and pelvic/abdominal pain in women who are having inflammatory changes in their cervicovaginal smears.
Materials and Methods: The cervicovaginal smears of 854 women, between the ages of 18 and 76 (38.7 ± 11.18) years, were evaluated. Papanicolaou staining was used for cytological evaluation. For the diagnosis of inflammation, polymorphonuclear leucocytes (PMNLs) were counted in at least five visual fields (×100). PMNLs counts “above 40” were recorded as inflammation positive.
Results: Inflammation was detected in 115 of the 854 (13.5%) patients; these were considered the study group. Cytological specimens with various types of infections and epithelial cell abnormalities were excluded from the cohort (n = 221, 25.8%). Patients without any infection (n = 518, 60.7%) were accepted as the control group. In the study group, gynecological complaints including vaginal discharge, pruritus, burning, odor, and abdominal pain were found at rates of 56.5%, 6.1%, 3.5%, 4.3%, and 7.8%, respectively. The presence of vaginal discharge was statistically significant in women with inflammation (56.5%) compared to the control group (25.9%).
Conclusion: Vaginal discharge is significantly more frequent in women with inflammatory changes in their cervicovaginal smears.

Keywords

Inflammation, Papanicolaou staining, vaginal discharge, cervicovaginal smears

Servikovajinal smearlarında inflamatuar değişiklikler bulunan kadınların jinekolojik şikayetlerinin değerlendirilmesi

Abstract

Amaç: İnflamasyon Pap-testinde yaygın olarak rapor edilmektedir, ancak klinik önemi konusunda bir fikir birliği yoktur. Servikovajinal simirlerde inflamatuar değişiklikler olan kadınlarda vajinal akıntı, kaşıntı, yanma, koku, pelvik/karın ağrısı gibi jinekolojik şikayetlerin varlığını araştırılması amaçlanmıştır.
Gereç ve Yöntem: 18-76 (38.7 ± 11.18) yaşları arasındaki 854 kadının servikovajinal simirleri değerlendirildi. Papanicolaou boyama yöntemi sitolojik değerlendirme için kullanıldı. İnflamsyon teşhisi için, polimorfonükleer lökositler (PMNL'ler) en az beş görsel alanda (×100) sayıldı. "40'ın üzerindeki" PMNL sayıları, inflamasyon pozitif olarak kaydedildi.
Bulgular: 854 hastanın 115'inde (%13.5) inflamasyon tespit edildi; bunlar çalışma grubu olarak kabul edildi. Çeşitli enfeksiyon türleri ve epitel hücre anormallikleri olan sitolojik örnekler kohorttan çıkarıldı (n = 221, %25,8). Herhangi bir enfeksiyonu olmayan hastalar ise (n = 518, %60,7) kontrol grubu olarak kabul edildi. Çalışma grubunda vajinal akıntı, kaşıntı, yanma, koku ve karın ağrısı gibi jinekolojik şikayetler sırasıyla %56,5, %6,1, %3,5, %4,3 ve %7,8 oranında bulundu. İnflamasyonlu kadınlarda vajinal akıntı varlığı (%56.5) kontrol grubuna (%25.9) göre istatistiksel olarak anlamlıydı.
Sonuç: Vajinal akıntı, servikovajinal smearlarında inflamatuvar değişiklikler olan kadınlarda anlamlı olarak daha sıktır.

Keywords

İnflamasyon, Papanicolaou boyama yöntemi, vajinal akıntı, servikovajinal simir

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