Primer perkütan koroner girişim uygulanan ST-segment yükseklikli miyokard infarktüslü hastalarda platelet/lenfosit oranı ile no-reflow oluşumu arasındaki ilişki

Year 2021, Volume: 46 Issue: 4, 1441 - 1448, 30.12.2021

Çağlar Özmen Anıl Akray Abdulkadir İltaş Pınar Özmen Yıldız İbrahim Yıldız Halil Aktaş

https://doi.org/10.17826/cumj.977656

Abstract

Amaç: Bu çalışmanın amacı, primer perkütan koroner girişim (PKG) ile tedavi edilen akut ST-segment yükselmeli miyokard infarktüsü (STYMİ) hastalarında başvuru sırasında ölçülen platelet/lenfosit oranının (PLO) ile no-reflow fenomeni oluşumu arasındaki ilişkiyi değerlendirmektir.
Gereç ve Yöntem: Bu çalışmada, primer PKG ile tedavi edilen akut STYMİ'li 126 hasta kapsanmıştırr. Hastaların hastaneye başvuru anındaki hemoglobin, trombosit ve lenfosit düzeyleri dosya verilerinden elde edildi. Hastaların işlem sonrasındaki miyokard infarktüsünde tromboliz (TIMI) akım derecesi, miyokardın boyanma derecesi (MBG) ve TIMI trombüs ölçeği koroner anjiyografi kayıtlarından değerlendirildi.
Bulgular: Hastalar PKG sonrası TIMI akım derecesine göre normal koroner akım (s=66) grubu ve azalmış koroner akım (no-reflow) grubu (s=60) olmak üzere iki gruba ayrıldı. No-reflow grupta normal koroner akım grubu ile kıyaslandığında daha düşük SVEF ve daha yüksek PLO vardı. TIMI akım derecesi ve MBG' si daha düşük olan hastalarda, PLO anlamlı olarak daha yüksekti.
Sonuç: Primer PKG sonrasında no-reflow gelişen STYMİ hastalarında başvuru sırasında ölçülen PLO daha yüksek saptanmıştır. PLO, bu tür hastalarda no-reflow için bir öngörürücü olarak kullanılabilir.

Keywords

lenfosit, miyokard infarktüsü, no-reflow, perkutan koroner girişim

Relationship between platelet/lymphocyte ratio and no-reflow formation in patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention

Abstract

Purpose: This study aims to evaluate the relationship between the platelet/lymphocyte ratio (PLR) measured at admission and the occurrence of no-reflow phenomenon in patients with acute ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI).
Materials and Methods: This study included 126 patients with acute STEMI treated with primary PCI. Hemoglobin, thrombocyte, and lymphocyte levels of the patients were retrieved from the files at the time of admission. Postprocedural thrombolysis in myocardial infarction (TIMI) flow grade, postprocedural myocardial blush grade (MBG), and TIMI thrombus scale were evaluated from the coronary angiography records.
Results: Patients were divided into two groups according to TIMI flow grade after PCI as normal coronary flow (n = 66) and no-reflow groups (n = 60). The no-reflow group had lower LVEF and higher PLR compared to the normal coronary flow group PLR was significantly higher in patients with lower TIMI flow grade and MBG.
Conclusion: PLR measured at admission was found to be higher in STEMI patients who developed no-reflow after primary PCI compared to the normal coronary flow group. PLR can be used as a predictor for no-reflow in such patients.

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