Disseminated peritoneal leiomyomatosis is a benign and very rare disease usually affecting premenopausal women. We present a 39 year old lady with intramural leiomyoma and disseminated peritoneal leiomyomatosis. The definitive treatment of disseminated peritoneal leiomyomatosis is surgical, depending on the degree of the disease. Before deciding on aggressive treatment, it should be kept in mind that peritoneal fibroids can mimic malignant peritoneal tumors.
References
1. Wilson JL, Peale AR. Multiple peritoneal leiomyomas associated with a granulosa-cell tumor of the ovary. Am J Obstet Gynecol. 1952;64:204–8.
2. Fasih N, Prasad ShanbhogueAK, Macdonald DB. Leiomyomas beyond the uterus: unusual locations, rare manifestations. Radiographics. 2008;28:1931–48.
3. Abulafia O, Angel C, Sherer DM, et al. Computed tomography of leiomyomatosis peritonealis disseminata with malignant transformation. Am J Obstet Gynecol. 1993;169:52–4.
4. Bekkers RL, Willemsen WN, Schijf CP, et al.Leiomyomatosis peritonealis disseminata: does malignant transformation occur? A literature review. Gynecol Oncol1999; 75: 158–63.
5. Raspagliesi F, Quattrone P, Grosso G, et al. Malignant degeneration in leiomyomatosis peritonealis disseminata. Gynecol Oncol 1996; 61: 272–4.
6. Travassoli FA, Norris HJ. Peritoneal leiomyomatosis (leiomyomatosis peritonealis disseminata): A clinicopathologic study of 20 cases with ultrastructural observations. Int J Gynecol Pathol. 1982;1:59–74. doi: 10.1097/00004347-198201000-00008.
7. Drake A, Dhundee J, Buckley CH, Woolas R. Disseminated leiomyomatosis peritonealis in association with oestrogen-secreting ovarian fibrothecoma. BJOG. 2001;108:661–4.
8. Surmacki P, Sporny S, Tosiak A, Lasota J. Disseminated peritoneal leiomyomatosis coexisting with leiomyoma of the uterine body. Arch Gynecol Obstet. 2006;273:301–3.
9. Ramesh L, Edozien L. Not all disseminated intra-abdominal lesions are malignant: A case of leiomyomatosis peritonealis disseminata. J Obstet Gynaecol. 2005;25:409.
10. Altinok G, Usubutun A, Küçükali T. Disseminated peritoneal leiomyomatosisA benign entity mimicking carcinomatosis. Arch Gynecol Obstet. 2000;264:54–5.
11. Saha PK, Dhaliwal LK, Gainder S, Bagga R, Joshi B, Saha SC, et al. Disseminated peritoneal leiomyomatosis: a rare entity with diagnostic conundrum. Int J Reprod Contracept Obstet Gynecol. 2015;4:1194–1196.
12. Al-Talib A, Tulandi T. Pathophysiology and Possible Iatrogenic Cause of Leiomyomatosis Peritonealis Disseminata. Gynecol Obstet Invest. 2010;69:239–44.
13. Sekulic M, Moench L, Movahedi-Lankarani S. Disseminated peritoneal leiomyomatosis postmorcellated resection of uterine leiomyomatous tissue. APMIS. 2016;124:1063–1071.
14. Travassoli FA, Norris HJ. Peritoneal leiomyomatosis (leiomyomatosis peritonealis disseminata): A clinicopathologic study of 20 cases with ultrastructural observations. Int J Gynecol Pathol. 1982;1:59–74. doi: 10.1097/00004347-198201000-00008.
16. Fulcher AS, Szucs RA. Leiomyomatosis peritonealis disseminata complicated by sarcomatous transformation and ovarian torsion: presentation of two cases and review of the literature. Abdom Imaging 1998; 23: 640–4.
17. Herrero J, Kamali P, Kirschbaum M. Leiomyomatosis peritonealis disseminata associated with endometriosis: a case report and literature review. Eur J Obstet Gynecol Reprod Biol 1998; 76: 189–91.
18. Kruczynski D, Merz E, Beck T, et al. Minimally invasive therapy of peritoneal leiomyomatosis. A case report of diagnostic and therapeutic problems [in German]. Geburtshilfe Frauenheilkd 1994; 54: 181–3.
Peritoneal karsinomatozisi taklit eden dissemine peritoneal leiomyomatozis
Year 2022,
Volume: 47 Issue: 3, 1369 - 1371, 30.09.2022
Dissemine peritoneal leiomyomatozis (DPL) genellikle premenopozal kadınları etkileyen iyi huylu ve çok nadir bir hastalıktır. 39 yaşında intramural leiomyomu ve dissemine peritoneal leiomyomatozisi olan bir kadın hastayı sunuyoruz. DPL'in kesin tedavisi hastalığın derecesine göre değişen derecede cerrahi olarak yapılmaktadır. Agresif tedavi kararı verilmeden önce peritoneal fibroidlerin malign peritoneal tümörleri taklit edebileceği akılda tutulmalıdır.
1. Wilson JL, Peale AR. Multiple peritoneal leiomyomas associated with a granulosa-cell tumor of the ovary. Am J Obstet Gynecol. 1952;64:204–8.
2. Fasih N, Prasad ShanbhogueAK, Macdonald DB. Leiomyomas beyond the uterus: unusual locations, rare manifestations. Radiographics. 2008;28:1931–48.
3. Abulafia O, Angel C, Sherer DM, et al. Computed tomography of leiomyomatosis peritonealis disseminata with malignant transformation. Am J Obstet Gynecol. 1993;169:52–4.
4. Bekkers RL, Willemsen WN, Schijf CP, et al.Leiomyomatosis peritonealis disseminata: does malignant transformation occur? A literature review. Gynecol Oncol1999; 75: 158–63.
5. Raspagliesi F, Quattrone P, Grosso G, et al. Malignant degeneration in leiomyomatosis peritonealis disseminata. Gynecol Oncol 1996; 61: 272–4.
6. Travassoli FA, Norris HJ. Peritoneal leiomyomatosis (leiomyomatosis peritonealis disseminata): A clinicopathologic study of 20 cases with ultrastructural observations. Int J Gynecol Pathol. 1982;1:59–74. doi: 10.1097/00004347-198201000-00008.
7. Drake A, Dhundee J, Buckley CH, Woolas R. Disseminated leiomyomatosis peritonealis in association with oestrogen-secreting ovarian fibrothecoma. BJOG. 2001;108:661–4.
8. Surmacki P, Sporny S, Tosiak A, Lasota J. Disseminated peritoneal leiomyomatosis coexisting with leiomyoma of the uterine body. Arch Gynecol Obstet. 2006;273:301–3.
9. Ramesh L, Edozien L. Not all disseminated intra-abdominal lesions are malignant: A case of leiomyomatosis peritonealis disseminata. J Obstet Gynaecol. 2005;25:409.
10. Altinok G, Usubutun A, Küçükali T. Disseminated peritoneal leiomyomatosisA benign entity mimicking carcinomatosis. Arch Gynecol Obstet. 2000;264:54–5.
11. Saha PK, Dhaliwal LK, Gainder S, Bagga R, Joshi B, Saha SC, et al. Disseminated peritoneal leiomyomatosis: a rare entity with diagnostic conundrum. Int J Reprod Contracept Obstet Gynecol. 2015;4:1194–1196.
12. Al-Talib A, Tulandi T. Pathophysiology and Possible Iatrogenic Cause of Leiomyomatosis Peritonealis Disseminata. Gynecol Obstet Invest. 2010;69:239–44.
13. Sekulic M, Moench L, Movahedi-Lankarani S. Disseminated peritoneal leiomyomatosis postmorcellated resection of uterine leiomyomatous tissue. APMIS. 2016;124:1063–1071.
14. Travassoli FA, Norris HJ. Peritoneal leiomyomatosis (leiomyomatosis peritonealis disseminata): A clinicopathologic study of 20 cases with ultrastructural observations. Int J Gynecol Pathol. 1982;1:59–74. doi: 10.1097/00004347-198201000-00008.
16. Fulcher AS, Szucs RA. Leiomyomatosis peritonealis disseminata complicated by sarcomatous transformation and ovarian torsion: presentation of two cases and review of the literature. Abdom Imaging 1998; 23: 640–4.
17. Herrero J, Kamali P, Kirschbaum M. Leiomyomatosis peritonealis disseminata associated with endometriosis: a case report and literature review. Eur J Obstet Gynecol Reprod Biol 1998; 76: 189–91.
18. Kruczynski D, Merz E, Beck T, et al. Minimally invasive therapy of peritoneal leiomyomatosis. A case report of diagnostic and therapeutic problems [in German]. Geburtshilfe Frauenheilkd 1994; 54: 181–3.