Research Article
BibTex RIS Cite

Greater occipital nerve block in patients with primary headache and early term results

Year 2022, Volume: 47 Issue: 4, 1730 - 1737, 28.12.2022
https://doi.org/10.17826/cumj.1169425

Abstract

Purpose: Peripheral nerve blocks have long been used in headache treatment and greater occipital nerve (GON) blocks are the most frequently preferred peripheral nerve blocks in patients with headaches in the past years. In this study, the efficacy of GON blocks in patients with primary headache disorders was evaluated.
Materials and Methods: This retrospective cohort study was undertaken in April 2021 and April 2022. One hundred twenty-one patients with primary headache disorders were included. Changes in the duration and frequency of headache attacks, pain severity, and type of oral medication before and after the injection treatment during the first and third months of follow-up were evaluated.
Results: The number of headache attacks decreased from 13 to 5 and the visual analogue scale(VAS) score decreased from 9 to 5 at the end of the third month in the migraine group. Similarly, the number of headache attacks decreased from 17 to 7 and the VAS score decreased from 8 to 4 in tension-type headache (TTH) group. Improvements in all parameters were found to be statistically significant in both groups.
Conclusion: GON block is a low-cost, rapid and minimally invasive treatment, and our data support that this method can be an effective treatment option in patients with migraine and TTH who are resistant to oral medication by reducing the number, frequency and severity of headache attacks. In conclusion, GON blockade should be considered by clinicians as a primary treatment option in patients with migraine and TTH resistant to oral medication.

References

  • 1. Tai MLS, Jivanadham JS, Tan CT, Sharma VK. Primary headache in the elderly in South-East Asia. J Headache Pain. 2012;13(4):291–7.
  • 2. Arnold M. Headache classification committee of the international headache society (IHS) the international classification of headache disorders. Cephalalgia. 2018;38(1):1–211.
  • 3. Zarifoğlu M, Güldoğuş F, Güleç S, N. Uçkunkaya. Baş ve Yüz Ağrıları. Ankara: Güneş Kitabevi; 2007. 13–31 p.
  • 4. Levin M. Nerve blocks in the treatment of headache. Neurotherapeutics. 2010;7(2):197–203.
  • 5. Kerr FW, Olafson RA. Trigeminal and cervical volleys. Convergence on single units in the spinal gray at C-1 and C-2. Arch Neurol. 1961;5:171–8.
  • 6. Bartsch, T., & Goadsby PJ. Stimulation of the greater occipital nerve induces increased central excitability of dural afferent input. Brain. 2002;125(7):1496–509.
  • 7. Inan, L. E., Inan, N., Unal-Artık, H. A., Atac, C., & Babaoglu G. Greater occipital nerve block in migraine prophylaxis: Narrative review. Cephalalgia. 2019;39(7):908–20.
  • 8. Goadsby PJ, Sprenger T. Current practice and future directions in the prevention and acute management of migraine. Lancet Neurol. 2010;9(3):285–98.
  • 9. Silberstein SD, Holland S, Freitag F, Dodick DW, Argoff C, Ashman E. Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology. 2012;78(17):1337–45.
  • 10. Özge A, Uludüz D, Yalın OÖ, Uygunoğlu U. Kronik migren: hastalık yükü, komorbidite ve tedavi. Turk Noroloji Derg. 2018;24(2):117.
  • 11. Selekler MH. Büyük oksipital sinir blokajı: Trigeminoservikal sistem ve primer başağrılarındaki klinik uygulamalar. Ağrı. 2008;20(3):6–13.
  • 12. Afridi SK, Shields KG, Bhola R, Goadsby PJ. Greater occipital nerve injection in primary headache syndromes–prolonged effects from a single injection. Pain. 2006;122(1–2):126–9.
  • 13. Vos T, Barber RM, Bell B, Bertozzi-Villa, A. B, S., Bolliger I, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;386(9995):743–800.
  • 14. Zhang H, Yang X, Lin Y, Chen L, Ye H. The efficacy of greater occipital nerve block for the treatment of migraine: a systematic review and meta-analysis. Clin Neurol Neurosurg. 2018;165:129–33.
  • 15. Leinisch-Dahlke, E., Jürgens T, Bogdahn U, Jakob W, May A. Greater occipital nerve block is ineffective in chronic tension type headache. Cephalalgia. 2005;25(9):704–8.
  • 16. Terzi T, Karakurum B, Üçler S, İnan LE, Tulunay C. Greater occipital nerve blockade in migraine, tension-type headache and cervicogenic headache. he J Headache Pain. 2002;3(3):137–41.
  • 17. Peres MFP, Stiles MA, Siow HC, Rozen TD, Young WB, Silberstein SD. Greater occipital nerve blockade for cluster headache. Cephalalgia. 2002;22(7):520–2.
  • 18. Weatherall MW. Idiopathic trigeminal neuropathy may respond to greater occipital nerve injection. Cephalalgia. 2008;28(6):664–6.
  • 19. Blumenfeld A, Ashkenazi A, Napchan U, Bender SD, Klein BC, Berliner R, et al. Expert consensus recommendations for the performance of peripheral nerve blocks for headaches–a narrative review. Headache J Head Face Pain. 2013;53(3):437–46.
  • 20. Dilli E, Halker R, Vargas B, Hentz J, Radam T, Rogers R, et al. Occipital nerve block for the short-term preventive treatment of migraine: a randomized, double-blinded, placebo-controlled study. Cephalalgia. 2015;35(11):959–68.
  • 21. Kashipazha D, Nakhostin-Mortazavi A, Mohammadianinejad SE, Bahadoram M, Zandifar S, Tarahomi S. Preventive effect of greater occipital nerve block on severity and frequency of migraine headache. Glob J Health Sci. 2014;6(6):209.
  • 22. Ashkenazi A, Matro R, Shaw JW, Abbas MA, Silberstein SD. Greater occipital nerve block using local anaesthetics alone or with triamcinolone for transformed migraine: a randomised comparative study. ournal Neurol Neurosurg Psychiatry. 2008;79(4):415–7.
  • 23. Ünal-Artık HA, İnan LE, Ataç-Uçar C, Yoldaş TK. Do bilateral and unilateral greater occipital nerve block effectiveness differ in chronic migraine patients?. Neurol Sci. 2017;38(6):949–54.
  • 24. Piñero MR, Carrillo PM, Hueso MP, de la Cruz Rodríguez C, Mesonero LL, Peral AG. Pericranial nerve blockade as a preventive treatment for migraine: Experience in 60 patients. Neurol (English Ed. 2016;31(7):445–51.

Primer baş ağrılı hastalarda büyük oksipital sinir blokajı ve erken dönem sonuçları

Year 2022, Volume: 47 Issue: 4, 1730 - 1737, 28.12.2022
https://doi.org/10.17826/cumj.1169425

Abstract

Amaç: Büyük oksipital sinir [greater occipital nerve (GON)] blokajı son yıllarda baş ağrılı hastalarda en sık tercih edilen periferik sinir blokajlarındandır. Bu çalışmada primer baş ağrılı hastalarda GON blokajının etkinliği değerlendirilmiştir.
Gereç ve Yöntem: Bu retrospektif kohort çalışması Nisan 2021 ve Nisan 2022'de yapılmıştır. Birincil baş ağrısı bozukluğu olan yüz yirmi bir hasta dahil edilmiştir. İzlemin 1. ve 3. ayında enjeksiyon tedavisi öncesi ve sonrası baş ağrısı ataklarının süresi ve sıklığı, ağrı şiddeti ve oral ilaç tipindeki değişiklikler değerlendirildi..
Bulgular: 3. ayın sonunda migren grubunda aylık baş ağrısı atak sayısı 13’ten 5’e ve vizuel analog skala(VAS) skoru 9’dan 5’e düşmüştü. Benzer şekilde gerilim tipi baş ağrısı (GTB) grubunda aylık baş ağrısı atak sayısı 17’den 7’ye ve VAS skoru 8’den 4’e düşmüştü. Her iki grupta da tüm paremetrelerdeki iyileşmeler istatiksel olarak anlamlıydı.
Sonuç: GON bloğu, düşük maliyetli, hızlı ve minimal invaziv bir yöntemdir ve verilerimiz, bu yöntemin baş ağrısı ataklarının sayısını, sıklığını ve şiddetini azaltarak, ağızdan ilaç tedavisine dirençli migren ve GTB hastalarında etkili bir tedavi yöntemi olabileceğini göstermiştir. Sonuç olarak GON blokajı klinisyenlerce ağızdan ilaç tedavisine dirençli migren ve GTB hastalarında öncelikli bir tedavi seçeneği olarak düşünülmelidir.

References

  • 1. Tai MLS, Jivanadham JS, Tan CT, Sharma VK. Primary headache in the elderly in South-East Asia. J Headache Pain. 2012;13(4):291–7.
  • 2. Arnold M. Headache classification committee of the international headache society (IHS) the international classification of headache disorders. Cephalalgia. 2018;38(1):1–211.
  • 3. Zarifoğlu M, Güldoğuş F, Güleç S, N. Uçkunkaya. Baş ve Yüz Ağrıları. Ankara: Güneş Kitabevi; 2007. 13–31 p.
  • 4. Levin M. Nerve blocks in the treatment of headache. Neurotherapeutics. 2010;7(2):197–203.
  • 5. Kerr FW, Olafson RA. Trigeminal and cervical volleys. Convergence on single units in the spinal gray at C-1 and C-2. Arch Neurol. 1961;5:171–8.
  • 6. Bartsch, T., & Goadsby PJ. Stimulation of the greater occipital nerve induces increased central excitability of dural afferent input. Brain. 2002;125(7):1496–509.
  • 7. Inan, L. E., Inan, N., Unal-Artık, H. A., Atac, C., & Babaoglu G. Greater occipital nerve block in migraine prophylaxis: Narrative review. Cephalalgia. 2019;39(7):908–20.
  • 8. Goadsby PJ, Sprenger T. Current practice and future directions in the prevention and acute management of migraine. Lancet Neurol. 2010;9(3):285–98.
  • 9. Silberstein SD, Holland S, Freitag F, Dodick DW, Argoff C, Ashman E. Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology. 2012;78(17):1337–45.
  • 10. Özge A, Uludüz D, Yalın OÖ, Uygunoğlu U. Kronik migren: hastalık yükü, komorbidite ve tedavi. Turk Noroloji Derg. 2018;24(2):117.
  • 11. Selekler MH. Büyük oksipital sinir blokajı: Trigeminoservikal sistem ve primer başağrılarındaki klinik uygulamalar. Ağrı. 2008;20(3):6–13.
  • 12. Afridi SK, Shields KG, Bhola R, Goadsby PJ. Greater occipital nerve injection in primary headache syndromes–prolonged effects from a single injection. Pain. 2006;122(1–2):126–9.
  • 13. Vos T, Barber RM, Bell B, Bertozzi-Villa, A. B, S., Bolliger I, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;386(9995):743–800.
  • 14. Zhang H, Yang X, Lin Y, Chen L, Ye H. The efficacy of greater occipital nerve block for the treatment of migraine: a systematic review and meta-analysis. Clin Neurol Neurosurg. 2018;165:129–33.
  • 15. Leinisch-Dahlke, E., Jürgens T, Bogdahn U, Jakob W, May A. Greater occipital nerve block is ineffective in chronic tension type headache. Cephalalgia. 2005;25(9):704–8.
  • 16. Terzi T, Karakurum B, Üçler S, İnan LE, Tulunay C. Greater occipital nerve blockade in migraine, tension-type headache and cervicogenic headache. he J Headache Pain. 2002;3(3):137–41.
  • 17. Peres MFP, Stiles MA, Siow HC, Rozen TD, Young WB, Silberstein SD. Greater occipital nerve blockade for cluster headache. Cephalalgia. 2002;22(7):520–2.
  • 18. Weatherall MW. Idiopathic trigeminal neuropathy may respond to greater occipital nerve injection. Cephalalgia. 2008;28(6):664–6.
  • 19. Blumenfeld A, Ashkenazi A, Napchan U, Bender SD, Klein BC, Berliner R, et al. Expert consensus recommendations for the performance of peripheral nerve blocks for headaches–a narrative review. Headache J Head Face Pain. 2013;53(3):437–46.
  • 20. Dilli E, Halker R, Vargas B, Hentz J, Radam T, Rogers R, et al. Occipital nerve block for the short-term preventive treatment of migraine: a randomized, double-blinded, placebo-controlled study. Cephalalgia. 2015;35(11):959–68.
  • 21. Kashipazha D, Nakhostin-Mortazavi A, Mohammadianinejad SE, Bahadoram M, Zandifar S, Tarahomi S. Preventive effect of greater occipital nerve block on severity and frequency of migraine headache. Glob J Health Sci. 2014;6(6):209.
  • 22. Ashkenazi A, Matro R, Shaw JW, Abbas MA, Silberstein SD. Greater occipital nerve block using local anaesthetics alone or with triamcinolone for transformed migraine: a randomised comparative study. ournal Neurol Neurosurg Psychiatry. 2008;79(4):415–7.
  • 23. Ünal-Artık HA, İnan LE, Ataç-Uçar C, Yoldaş TK. Do bilateral and unilateral greater occipital nerve block effectiveness differ in chronic migraine patients?. Neurol Sci. 2017;38(6):949–54.
  • 24. Piñero MR, Carrillo PM, Hueso MP, de la Cruz Rodríguez C, Mesonero LL, Peral AG. Pericranial nerve blockade as a preventive treatment for migraine: Experience in 60 patients. Neurol (English Ed. 2016;31(7):445–51.
There are 24 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Research
Authors

Hasan Hüseyin Kır 0000-0001-5496-7397

Publication Date December 28, 2022
Acceptance Date November 28, 2022
Published in Issue Year 2022 Volume: 47 Issue: 4

Cite

MLA Kır, Hasan Hüseyin. “Greater Occipital Nerve Block in Patients With Primary Headache and Early Term Results”. Cukurova Medical Journal, vol. 47, no. 4, 2022, pp. 1730-7, doi:10.17826/cumj.1169425.