Ficus carica çekirdek yağının renoprotektif aktivitesi

Year 2024, Volume: 49 Issue: 3, 851 - 852, 30.09.2024

Ferhat Şirinyıldız

https://doi.org/10.17826/cumj.1439116

Abstract

Ficus carica tohumu yağı, herkes tarafından kullanılabilecek ve insanların diyetlerine entegre edilebilecek özelliklere sahiptir. Erişilebilirliğinin yanı sıra, uzun süreli kullanımı böbrek hasarına karşı hem koruyucu hem de tedavi edici etkilere sahiptir. Daha ileri çalışmalar, etkinliğinin altında yatan moleküler mekanizmaları aydınlatmalı ve farmakokinetik özelliklerini belirlemelidir.

Keywords

Antioksidan, Antiinflamasyon, Renoproteksiyon, Ficus carica tohumu yağı

Ethical Statement

Etik izne ihtiyaç yoktur.

Supporting Institution

-

Project Number

-

Thanks

-

Renoprotective activity of Ficus carica seed oil

Abstract

Ficus carica seed oil possesses properties that can be used by everyone and can be integrated into people's diets. In addition to its accessibility, its long-term use has both protective and therapeutic effects against kidney damage. Further studies should elucidate the molecular mechanisms underlying its efficacy and determine its pharmacokinetic properties.

Keywords

Antioxidant, Antiinflammation, Renoprotection, Ficus carica seed oil

Ethical Statement

No ethical approval is required.

Supporting Institution

-

Project Number

-

Thanks

-

References

• Badgujar SB, Patel VV, Bandivdekar AH, Mahajan RT. Traditional uses, phytochemistry and pharmacology of Ficus carica: A review. Pharm Biol. 2014;52:1487-503.
• Bouyahya A, Bensaid M, Bakri Y, Dakka N. Phytochemistry and ethnopharmacology of Ficus carica. Int J Biochem Res Rev. 2016;14:1-12.
• Orak C, Şirinyıldız F, Yılmaz EG, Cesur G, Ek RO. Protective effects of Ficus carica seed oil on ischemia and reperfusion injury in a rat model of acute mesenteric ischemia. Ulus Travma Acil Cerrahi Derg. 2021;27:402-9.
• İşler D, Şirinyıldız F, Ek RO. Effect of Ficus carica (fig) seed oil administration on GSH levels, necrosis and cast formation in myoglobinuric acute kidney injury. Cukurova Medical Journal. 2022;47:152–60.
• Serkan U, Yarılgaç T. Germencik (Aydın) ilçesinde yetiştirilen Sarılop incirlerinde (Ficus carica L.) klon seleksiyonu. Uluslararası Tarım ve Yaban Hayatı Bilimleri Dergisi. 2021;7:1–8.
• Kalantar-Zadeh K, Jafar TH, Nitsch D, Neuen BL, Perkovic V. Chronic kidney disease. Lancet. 2021;398:786–802.
• Ates HA, Yücetaş U, Erkan E, Yucetas E, Ulusoy S, Kadihasanoglu M et al. The predictive value of ischemia-modified albumin in renal ischemia-reperfusion injury. Urol Int. 2019;103:473–81.
• Shiva N, Sharma N, Kulkarni YA, Mulay SR, Gaikwad AB. Renal ischemia/reperfusion injury: An insight on in vitro and in vivo models. Life Sci. 2020;256:117860.
• Şirinyıldız F, Serdal Ö. The effects of Ficus carica Seed oil administration on renal TAS, TOS, OSI, PON and total thiol values in renal ischemia reperfusion damage. Turkish Journal of Health Science and Life. 2023;6:156–60.
• Güven N, Gökyer A, Koç A, Temiz NN, Selvi S, Koparal B et al. Physiochemical composition of fig seed oil from Turkey. J Pharm Pharmacol. 2019;7:541–5