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A review of Moroccan medicinal plants used in the treatment of urolithiasis

Year 2022, Volume: 5 Issue: 1, 63 - 73, 30.06.2022
https://doi.org/10.38093/cupmap.1078416

Abstract

In Morocco, surveys on the medicinal plants used in the treatment of urolithiasis have been carried out by various researchers during ethnobotanical missions.
The main objective of this work is to contribute to the knowledge of medicinal plants used in the treatment of this disease in Morocco in order to help in the formulation of improved traditional medicines.
Data concerning the use of medicinal plants against urolithiasis are extracted from published documents concerning the various ethnomedicinal surveys conducted in Morocco for synthesis and analysis. In total, 82 species of plants belonging to 42 families are recorded to be used by the Moroccan population to treat urolithiasis. Apiaceae, Lamiaceae, Leguminosae and Poaceae are the most represented families. The most cited plant species are Petroselinum crispum and Citrus limon, Atriplex halimus, Apium graveolens, Opuntia ficus-indica and Herniaria hirsute. Several parts of the plant are solicited. Nevertheless the seeds and the leaves are the most used parts. Decoction and infusion are the most common methods of preparation.
Morocco has an important floristic biodiversity in terms of antilithiasic plants. These results form the basis of subsequent studies aimed at experimentally evaluating the potential of these plants.

References

  • 1. Aggarwal, A., Singla, S., and Tandon, C., 2014. Urolithiasis: Phytotherapy as an adjunct therapy.
  • 2. Ahmed, A., Wadud, A., Jahan, N., Bilal, A., and Hajera, S., 2013. Efficacy of Adiantum capillus veneris Linn in chemically induced urolithiasis in rats. Journal of ethnopharmacology, 146(1), 411-416.
  • 3. Amin, B., Feriz, H.M., Hariri, A.T., Meybodi, N.T., and Hosseinzadeh, H., 2015. Protective effects of the aqueous extract of Crocus sativus against ethylene glycol induced nephrolithiasis in rats. EXCLI journal, 14, 411.
  • 4. Atmani, F., 2003. Medical management of urolithiasis, what opportunity for phytotherapy. Front Biosci, 8(6), 507-514.
  • 5. Atmani, F., Farell, G., and Lieske, J.C., 2004. Extract from Herniaria hirsuta coats calcium oxalate monohydrate crystals and blocks their adhesion to renal epithelial cells. The Journal of urology, 172(4), 1510-1514.
  • 6. Atmani, F., and Khan, S., 2000. Effects of an extract from Herniaria hirsuta on calcium oxalate crystallization in vitro. Bju International, 85(6), 621-625.
  • 7. Atmani, F., Sadki, C., Aziz, M., Mimouni, M., and Hacht, B., 2009. Cynodon dactylon extract as a preventive and curative agent in experimentally induced nephrolithiasis. Urological research, 37(2), 75-82.
  • 8. Atmani, F., Slimani, Y., Mimouni, M., Aziz, M., Hacht, B., and Ziyyat, A., 2004. Effect of aqueous extract from Herniaria hirsuta L. on experimentally nephrolithiasic rats. Journal of ethnopharmacology, 95(1), 87-93.
  • 9. Atmani, F., Slimani, Y., Mimouni, M., and Hacht, B., 2003. Prophylaxis of calcium oxalate stones by Herniaria hirsuta on experimentally induced nephrolithiasis in rats. BJU international, 92(1), 137-140.
  • 10. Bawari, S., Sah, A.N., and Tewari, D., 2018. Antiurolithiatic Activity of Daucus carota: An in vitro Study. Pharmacognosy Journal, 10(5).
  • 11. Beghalia, M., Ghalem, S., Allalia, H., Belouatek, A., and Marouf, A., 2009. Effects of Atriplex halimus and Ajuga iva L. Schreb on Calcium Oxalate Urolithiasis Risk in vitro. Asian Journal of Chemistry, 21(2), 1119.
  • 12. Biglarkhani, M., Amir Zargar, M.A., Hashem-Dabaghian, F., Amini Behbahani, F., and Meyari, A., 2019. Cicer arietinum in the treatment of small renal stones: a double-blind, randomized and placebo-controlled trial. Research Journal of Pharmacognosy, 6(1), 35-42.
  • 13. Butterweck, V., and Khan, S.R., 2009. Herbal medicines in the management of urolithiasis: alternative or complementary? Planta medica, 75(10), 1095-1103.
  • 14. Chaachouay, N., Benkhnigue, O., Khamar, H., and Zidane, L., Ethnobotanical study of medicinal and aromatic plants used in the treatment of genito-urinary diseases in the Moroccan Rif.
  • 15. Chandrasekaran, S., and Veerasamy, V., 2018. Anti-urolithiatic activity of whole plant aqueous and ethanolic extract of Coriandrum sativum L.-an in vitro approach. Malaya Journal of Biosciences (MJB), 5(1), 28-36.
  • 16. Cheraft-Bahloul, N., Husson, C., Ourtioualous, M., Sinaeve, S., Atmani, D., Stévigny, C., Nortier, J.L., and Antoine, M.-H., 2017. Protective Effects of Pistacia lentiscus L. fruit extract against calcium oxalate monohydrate induced proximal tubular injury. Journal of ethnopharmacology, 209, 248-254.
  • 17. Delfan, B., Baharvand-Ahmadi, B., Bahmani, M., Mohseni, N., Saki, K., Rafieian-Kopaei, M., Shahsavari, S., Naghdi, N., Taherikalani, M., and Ghafourian, S., 2015. An ethnobotanical study of medicinal plants used in treatment of kidney stones and kidney pain in Lorestan province, Iran. Journal of Chemical and Pharmaceutical Sciences, 8(4), 693-699.
  • 18. Fouada, A., Yamina, S., Nait, M.A., Mohammed, B., and Abdlekrim, R., 2006. In vitro and in vivo antilithiasic effect of saponin rich fraction isolated from herniaria hirsuta. J Bras Nefrol, 28(4), 199-203.
  • 19. Ghourri, M., Zidane, L., and Douira, A., 2013. Catalogue des plantes médicinales utilisées dans le traitement de la lithiase rénale dans la province de Tan-Tan (Maroc saharien). International Journal of Biological and Chemical Sciences, 7(4), 1688-1700.
  • 20. Grases, F., March, J., Ramis, M., and Costa‐Bauzá, A., 1993. The influence of Zea mays on urinary risk factors for kidney stones in rats. Phytotherapy research, 7(2), 146-149.
  • 21. Grases, F., Prieto, R.M., Gomila, I., Sanchis, P., and Costa-Bauzá, A., 2009. Phytotherapy and renal stones: the role of antioxidants. A pilot study in Wistar rats. Urological research, 37(1), 35.
  • 22. Hadjzadeh, M., Rad, A.K., Rajaei, Z., Tehranipour, M., and Monavar, N., 2011. The preventive effect of N-butanol fraction of Nigella sativa on ethylene glycol-induced kidney calculi in rats. Pharmacognosy magazine, 7(28), 338-343.
  • 23. Ibrahim, F.Y., and El-Khateeb, A., 2013. Effect of herbal beverages of Foeniculum vulgare and Cymbopogon proximus on inhibition of calcium oxalate renal crystals formation in rats. Annals of Agricultural Sciences, 58(2), 221-229.
  • 24. Idm'hand, E., Msanda, F., and Cherifi, K., 2019. Étude ethnobotanique des plantes médicinales utilisées dans le traitement de la lithiase urinaire dans la province de Tarfaya (Maroc). International Journal of Innovation and Applied Studies, 26(3), 711-719.
  • 25. Khajavi Rad, A., Hajzadeh, M.-A.-R., Rajaei, Z., Sadeghian, M.-H., Hashemi, N., and Keshavarzi, Z., 2011. Preventive effect of Cynodon dactylon against ethylene glycol-induced nephrolithiasis in male rats. Avicenna Journal of Phytomedicine, 1(1), 14-23.
  • 26. Khan, Z.A., Assiri, A.M., Al-Afghani, H.M., and Maghrabi, T.M., 2001. Inhibition of oxalate nephrolithiasis with Ammi visnaga (AI-Khillah). International urology and nephrology, 33(4), 605-608.
  • 27. Khoei, A., Hadjzadeh, Z., and Parizady, M., 2009. Ethanolic extract of nigella sativa L seeds on ethylene glycol-induced kidney calculi in rats. Urology journal, 4(2), 86-90.
  • 28. Khouchlaa, A., Tijane, M., Chebat, A., Hseini, S., and Kahouadji, A., 2017. Ethnopharmacology study of medicinal plants used in the treatment of urolithiasis (Morocco).
  • 29. Kumari, P., Singh, T., and Singh, P., 2016. Medicinal plants of buxar district of bihar used in treatment of urinary tract and kidney stones. Indian Journal of Life Sciences, 5(2), 37-42.
  • 30. Laroubi, A., Touhami, M., Farouk, L., Zrara, I., Aboufatima, R., Benharref, A., and Chait, A., 2007. Prophylaxis effect of Trigonella foenum graecum L. seeds on renal stone formation in rats. Phytotherapy Research, 21(10), 921-925.
  • 31. Rad, A.K., Rajaei, Z., Mohammadian, N., Valiollahi, S., and Sonei, M., 2011. The beneficial effect of Cynodon dactylon fractions on ethylene glycol-induced kidney calculi in rats. Urology journal, 8(3), 179-184.
  • 32. Rathod, N., Biswas, D., Chitme, H., Ratna, S., Muchandi, I., and Chandra, R., 2012. Anti-urolithiatic effects of Punica granatum in male rats. Journal of ethnopharmacology, 140(2), 234-238.
  • 33. Reddy, C.S., and Vardhaman, P., 2013. Evaluation of Phoenix dactylifera fruits for Antiurolithiatic activity. Hygeia. JD Med, 5(1), 135-140.
  • 34. Reddy, C.S., and Vardhaman, P., 2013. Evaluation of Phoenix dactylifera fruits for Antiurolithiatic activity. Hygeia. JD Med, 5(1), 135-140.2013.
  • 35. Shah, J.G., Patel, B.G., Patel, S.B., and Patel, R.K., 2012. Antiurolithiatic and antioxidant activity of Hordeum vulgare seeds on ethylene glycol-induced urolithiasis in rats. Indian journal of pharmacology, 44(6), 672.
  • 36. Siddiqui, W.A., Shahzad, M., Shabbir, A., and Ahmad, A., 2018. Evaluation of anti-urolithiatic and diuretic activities of watermelon (Citrullus lanatus) using in vivo and in vitro experiments. Biomedicine & Pharmacotherapy, 97, 1212-1221.
  • 37. Sinha, M.R., and Tagore, R., 2010. Effect of acid-hydrolyzation of fruits juice of apple (Malus domestica), Moushmi (Citrus medica) and Amla (Emblica officinalis) on solubility of urinary stones. Asian Journal of Chemistry, 22(6), 4840-4846.
  • 38. Touiti, N., Bousta, D., Boukhira, S., Chebaibi, M., and Achour, S., 2020. Phytochemical screening, acute and sub-acute toxicity of aqueous extract from a mixture of some recipe of Herniaria glabra L., Opuntia ficus-indica, Zea mays L. and Zizyphus lotus L. used traditionally against renal lithiases. Pharmacognosy Research, 12(1), 60.
Year 2022, Volume: 5 Issue: 1, 63 - 73, 30.06.2022
https://doi.org/10.38093/cupmap.1078416

Abstract

References

  • 1. Aggarwal, A., Singla, S., and Tandon, C., 2014. Urolithiasis: Phytotherapy as an adjunct therapy.
  • 2. Ahmed, A., Wadud, A., Jahan, N., Bilal, A., and Hajera, S., 2013. Efficacy of Adiantum capillus veneris Linn in chemically induced urolithiasis in rats. Journal of ethnopharmacology, 146(1), 411-416.
  • 3. Amin, B., Feriz, H.M., Hariri, A.T., Meybodi, N.T., and Hosseinzadeh, H., 2015. Protective effects of the aqueous extract of Crocus sativus against ethylene glycol induced nephrolithiasis in rats. EXCLI journal, 14, 411.
  • 4. Atmani, F., 2003. Medical management of urolithiasis, what opportunity for phytotherapy. Front Biosci, 8(6), 507-514.
  • 5. Atmani, F., Farell, G., and Lieske, J.C., 2004. Extract from Herniaria hirsuta coats calcium oxalate monohydrate crystals and blocks their adhesion to renal epithelial cells. The Journal of urology, 172(4), 1510-1514.
  • 6. Atmani, F., and Khan, S., 2000. Effects of an extract from Herniaria hirsuta on calcium oxalate crystallization in vitro. Bju International, 85(6), 621-625.
  • 7. Atmani, F., Sadki, C., Aziz, M., Mimouni, M., and Hacht, B., 2009. Cynodon dactylon extract as a preventive and curative agent in experimentally induced nephrolithiasis. Urological research, 37(2), 75-82.
  • 8. Atmani, F., Slimani, Y., Mimouni, M., Aziz, M., Hacht, B., and Ziyyat, A., 2004. Effect of aqueous extract from Herniaria hirsuta L. on experimentally nephrolithiasic rats. Journal of ethnopharmacology, 95(1), 87-93.
  • 9. Atmani, F., Slimani, Y., Mimouni, M., and Hacht, B., 2003. Prophylaxis of calcium oxalate stones by Herniaria hirsuta on experimentally induced nephrolithiasis in rats. BJU international, 92(1), 137-140.
  • 10. Bawari, S., Sah, A.N., and Tewari, D., 2018. Antiurolithiatic Activity of Daucus carota: An in vitro Study. Pharmacognosy Journal, 10(5).
  • 11. Beghalia, M., Ghalem, S., Allalia, H., Belouatek, A., and Marouf, A., 2009. Effects of Atriplex halimus and Ajuga iva L. Schreb on Calcium Oxalate Urolithiasis Risk in vitro. Asian Journal of Chemistry, 21(2), 1119.
  • 12. Biglarkhani, M., Amir Zargar, M.A., Hashem-Dabaghian, F., Amini Behbahani, F., and Meyari, A., 2019. Cicer arietinum in the treatment of small renal stones: a double-blind, randomized and placebo-controlled trial. Research Journal of Pharmacognosy, 6(1), 35-42.
  • 13. Butterweck, V., and Khan, S.R., 2009. Herbal medicines in the management of urolithiasis: alternative or complementary? Planta medica, 75(10), 1095-1103.
  • 14. Chaachouay, N., Benkhnigue, O., Khamar, H., and Zidane, L., Ethnobotanical study of medicinal and aromatic plants used in the treatment of genito-urinary diseases in the Moroccan Rif.
  • 15. Chandrasekaran, S., and Veerasamy, V., 2018. Anti-urolithiatic activity of whole plant aqueous and ethanolic extract of Coriandrum sativum L.-an in vitro approach. Malaya Journal of Biosciences (MJB), 5(1), 28-36.
  • 16. Cheraft-Bahloul, N., Husson, C., Ourtioualous, M., Sinaeve, S., Atmani, D., Stévigny, C., Nortier, J.L., and Antoine, M.-H., 2017. Protective Effects of Pistacia lentiscus L. fruit extract against calcium oxalate monohydrate induced proximal tubular injury. Journal of ethnopharmacology, 209, 248-254.
  • 17. Delfan, B., Baharvand-Ahmadi, B., Bahmani, M., Mohseni, N., Saki, K., Rafieian-Kopaei, M., Shahsavari, S., Naghdi, N., Taherikalani, M., and Ghafourian, S., 2015. An ethnobotanical study of medicinal plants used in treatment of kidney stones and kidney pain in Lorestan province, Iran. Journal of Chemical and Pharmaceutical Sciences, 8(4), 693-699.
  • 18. Fouada, A., Yamina, S., Nait, M.A., Mohammed, B., and Abdlekrim, R., 2006. In vitro and in vivo antilithiasic effect of saponin rich fraction isolated from herniaria hirsuta. J Bras Nefrol, 28(4), 199-203.
  • 19. Ghourri, M., Zidane, L., and Douira, A., 2013. Catalogue des plantes médicinales utilisées dans le traitement de la lithiase rénale dans la province de Tan-Tan (Maroc saharien). International Journal of Biological and Chemical Sciences, 7(4), 1688-1700.
  • 20. Grases, F., March, J., Ramis, M., and Costa‐Bauzá, A., 1993. The influence of Zea mays on urinary risk factors for kidney stones in rats. Phytotherapy research, 7(2), 146-149.
  • 21. Grases, F., Prieto, R.M., Gomila, I., Sanchis, P., and Costa-Bauzá, A., 2009. Phytotherapy and renal stones: the role of antioxidants. A pilot study in Wistar rats. Urological research, 37(1), 35.
  • 22. Hadjzadeh, M., Rad, A.K., Rajaei, Z., Tehranipour, M., and Monavar, N., 2011. The preventive effect of N-butanol fraction of Nigella sativa on ethylene glycol-induced kidney calculi in rats. Pharmacognosy magazine, 7(28), 338-343.
  • 23. Ibrahim, F.Y., and El-Khateeb, A., 2013. Effect of herbal beverages of Foeniculum vulgare and Cymbopogon proximus on inhibition of calcium oxalate renal crystals formation in rats. Annals of Agricultural Sciences, 58(2), 221-229.
  • 24. Idm'hand, E., Msanda, F., and Cherifi, K., 2019. Étude ethnobotanique des plantes médicinales utilisées dans le traitement de la lithiase urinaire dans la province de Tarfaya (Maroc). International Journal of Innovation and Applied Studies, 26(3), 711-719.
  • 25. Khajavi Rad, A., Hajzadeh, M.-A.-R., Rajaei, Z., Sadeghian, M.-H., Hashemi, N., and Keshavarzi, Z., 2011. Preventive effect of Cynodon dactylon against ethylene glycol-induced nephrolithiasis in male rats. Avicenna Journal of Phytomedicine, 1(1), 14-23.
  • 26. Khan, Z.A., Assiri, A.M., Al-Afghani, H.M., and Maghrabi, T.M., 2001. Inhibition of oxalate nephrolithiasis with Ammi visnaga (AI-Khillah). International urology and nephrology, 33(4), 605-608.
  • 27. Khoei, A., Hadjzadeh, Z., and Parizady, M., 2009. Ethanolic extract of nigella sativa L seeds on ethylene glycol-induced kidney calculi in rats. Urology journal, 4(2), 86-90.
  • 28. Khouchlaa, A., Tijane, M., Chebat, A., Hseini, S., and Kahouadji, A., 2017. Ethnopharmacology study of medicinal plants used in the treatment of urolithiasis (Morocco).
  • 29. Kumari, P., Singh, T., and Singh, P., 2016. Medicinal plants of buxar district of bihar used in treatment of urinary tract and kidney stones. Indian Journal of Life Sciences, 5(2), 37-42.
  • 30. Laroubi, A., Touhami, M., Farouk, L., Zrara, I., Aboufatima, R., Benharref, A., and Chait, A., 2007. Prophylaxis effect of Trigonella foenum graecum L. seeds on renal stone formation in rats. Phytotherapy Research, 21(10), 921-925.
  • 31. Rad, A.K., Rajaei, Z., Mohammadian, N., Valiollahi, S., and Sonei, M., 2011. The beneficial effect of Cynodon dactylon fractions on ethylene glycol-induced kidney calculi in rats. Urology journal, 8(3), 179-184.
  • 32. Rathod, N., Biswas, D., Chitme, H., Ratna, S., Muchandi, I., and Chandra, R., 2012. Anti-urolithiatic effects of Punica granatum in male rats. Journal of ethnopharmacology, 140(2), 234-238.
  • 33. Reddy, C.S., and Vardhaman, P., 2013. Evaluation of Phoenix dactylifera fruits for Antiurolithiatic activity. Hygeia. JD Med, 5(1), 135-140.
  • 34. Reddy, C.S., and Vardhaman, P., 2013. Evaluation of Phoenix dactylifera fruits for Antiurolithiatic activity. Hygeia. JD Med, 5(1), 135-140.2013.
  • 35. Shah, J.G., Patel, B.G., Patel, S.B., and Patel, R.K., 2012. Antiurolithiatic and antioxidant activity of Hordeum vulgare seeds on ethylene glycol-induced urolithiasis in rats. Indian journal of pharmacology, 44(6), 672.
  • 36. Siddiqui, W.A., Shahzad, M., Shabbir, A., and Ahmad, A., 2018. Evaluation of anti-urolithiatic and diuretic activities of watermelon (Citrullus lanatus) using in vivo and in vitro experiments. Biomedicine & Pharmacotherapy, 97, 1212-1221.
  • 37. Sinha, M.R., and Tagore, R., 2010. Effect of acid-hydrolyzation of fruits juice of apple (Malus domestica), Moushmi (Citrus medica) and Amla (Emblica officinalis) on solubility of urinary stones. Asian Journal of Chemistry, 22(6), 4840-4846.
  • 38. Touiti, N., Bousta, D., Boukhira, S., Chebaibi, M., and Achour, S., 2020. Phytochemical screening, acute and sub-acute toxicity of aqueous extract from a mixture of some recipe of Herniaria glabra L., Opuntia ficus-indica, Zea mays L. and Zizyphus lotus L. used traditionally against renal lithiases. Pharmacognosy Research, 12(1), 60.
There are 38 citations in total.

Details

Primary Language English
Subjects Pharmacology and Pharmaceutical Sciences
Journal Section Review Articles
Authors

Elhassan Idm'hand 0000-0001-9548-6231

Publication Date June 30, 2022
Published in Issue Year 2022 Volume: 5 Issue: 1

Cite

APA Idm’hand, E. (2022). A review of Moroccan medicinal plants used in the treatment of urolithiasis. Current Perspectives on Medicinal and Aromatic Plants, 5(1), 63-73. https://doi.org/10.38093/cupmap.1078416

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