Fabrication and Characterisation of YIG Doped Hydroxyapatite Composites

Abstract

In this study, the fabrication and characterization of Yttrium Iron Garnet (YIG) doped hydroxyapatite (HAp) composites were carried out. HAp is a bioceramic material known for its biocompatibility and osteogenic properties and is widely used in bone tissue engineering. However, the low mechanical strength and brittleness of HAp limit the use of this material in load-bearing applications. In order to overcome these deficiencies, it is aimed to improve both mechanical properties and magnetic properties of the material by adding YIG to HAp material. In the study, YIG powders were synthesized with the help of citric acid by sol-gel method using yttrium (Y) and iron (Fe) salts. Then, commercial HAp powders and YIG powders were mixed with 1, 2 and 3 wt. % of commercial HAp powders to obtain pellets and these pellets were sintered at 1200 °C for 3 hours. The produced composites were characterized by thermalgravimetric analysis (TG/DTA), X-ray diffraction (XRD), scanning electron microscopy (SEM), Raman spectroscopy, magnetic and wettability tests. In addition, the mechanical properties of the composites were analyzed by hardness measurements. Significant improvements in both the magnetic and mechanical properties of the obtained composites were observed with increasing YIG content. These new composites show potential for biomedical applications, especially for bone regeneration and cancer treatment.

Keywords

• Yttrium iron Garnet (YIG)
• Hydroxyapatite (HAp)
• Bioceramic Composites

YIG Katkılanmış Hidroksiapatit Kompozitlerinin Üretimi ve Karakterizasyonu

Abstract

Bu çalışmada, itriyum demir garnet (YIG) katkılı hidroksiapatit (HAp) kompozitlerinin üretimi ve karakterizasyonu gerçekleştirilmiştir. HAp, biyouyumluluğu ve osteojenik özellikleri ile bilinen bir biyoseramik malzeme olup, kemik doku mühendisliğinde yaygın olarak kullanılmaktadır. Ancak HAp'in düşük mekanik mukavemeti, bu malzemenin yük taşıyan uygulamalarda kullanımını kısıtlamaktadır. Bu eksiklikleri gidermek amacıyla HAp malzemesine YIG eklenerek, hem mekanik özelliklerin iyileştirilmesi hemde malzemeye manyetik özelliklerin kazandırılması hedeflenmiştir. Çalışmada, YIG tozları itriyum (Y) ve demir (Fe) tuzları kullanılarak sitrik asit yardımıyla sol-jel yöntemiyle sentezlenmiştir. Daha sonra, ticari HAp tozlarıyla elde edilen YIG tozları ağırlıkça % 1, 2 ve 3 oranlarda olacak şekilde karıştırılarak peletler elde edilmiştir ve bu peletler 1200°C'de 3 saat süreyle sinterlenmişlerdir. Üretilen kompozitler, termalgravimetrik analiz (TG/DTA), X ışını kırınımı (XRD), taramalı elektron mikroskobu (SEM), Raman spektroskopisi, manyetik ve ıslatılabilirlik testleri ile karakterize edilmişlerdir. Ayrıca üretilen kompozitlerin mekanik özellikleri sertlik ölçümleriyle incelenmiştir. Elde edilen kompozitlerin hem manyetik özelliklerinde hem de mekanik özelliklerinde YIG miktarının artmasıyla belirgin iyileşmeler olduğu gözlenmiştir. Bu yeni kompozitler, biyomedikal uygulamalarda, özellikle kemik rejenerasyonu ve kanser tedavisinde kullanılmak üzere potansiyel vadetmektedir.

Keywords

• Itriyum demir Garnet (YIG)
• Hidroksiapatit (HAp)
• Biyoseramik Kompozitler

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