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Bir Antibiyotik olan Trimetoprimin Sütunlu Kil ile Sulu Ortamdan Uzaklaştırılması

Year 2020, Volume: 22 Issue: 66, 949 - 963, 22.09.2020

Zehra Molu

https://doi.org/10.21205/deufmd.2020226628

Abstract

Son zamanlarda artan bilinçsiz antibiyotik kullanımı bakterilerin direnç kazanmasına ve antibiyotiklerin etkisinin azalmasına sebep vermektedir. Bu çalışmada bakterilerin gösterdiği direncin azalması ve sulu ortamdaki antibiyotik kirliliğinin giderilmesi için Fe-sütunlu montmorillonit K10 (Fe-K10) kullanarak bir antibiyotik olan trimetoprimin (TMP) adsorpsiyon deneyleri gerçekleştirildi. Adsorban olarak kullanılan Fe-K10 montmorillonit K10’un Fe iyonları ile montmorillonit K10’un sütunlama işlemi ile sentezlendikten sonra karakterizasyonu TGA, XRD, SEM and FT-IR spektroskopik analizlerle gerçekleştirildi. Karakterisazyon sonuçları Fe-K10’da kilin tabakalar arası mesafesinin arttığını ve adsorpsiyon için iyi bir ortam oluştuğunu göstermektedir. Trimetoprimin sulu ortamdan uzaklaştırılmasında sıcaklığın etkisi, denge zamanı, Fe-K10 miktarı ve çözelti pH etkisi araştırıldı. Adsorpsiyon kinetiği calışmaları sonucunda TMP’nin Fe-K10 üzerine adsorpsiyonunun yalancı-ikinci mertebe tepkime kinetiğine uyum gösterdiği bulundu. Termodinamik verileri ve izoterm verileri gerçekleştirilen adsorpsiyonun fiziksel olduğunu gösterdi. TMP’nin Fe-K10 ile sulu ortamdan uzaklaştırılma kapasitesi pH değerleri düştükçe azalmaktadır. Adsorban miktarının artışı antibiyotiğin uzaklaştırma yüzdesini artırmaktadır. Bu nedenlerle, yüksek pH ve yüksek adsorban miktarı değerlerinde Fe-K10 adsorbanının bir antibiyotik olan trimetoprimin sulu ortamdan uzaklaştırılmasında kullanılması hem ekonomik açıdan hem de sulardaki antibiyotik kirliliğinin önlenmesi açısından oldukça iyi bir sonuç verdiği bulundu.

Keywords

Trimetoprim Antibiyotik Fe-Sütunlu K10

Thanks

Bu çalışmanın yapılmasında destekleri olan Prof. Dr. Kadir Yurdakoç ve Prof. Dr. Mürürvvet Yurdakoç’a teşekkür ederim.

References

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  • Xu, W., Zhang, G., Zou S., Li, X., Liu Y. 2007. Determination of selected antibiotics in the Victoria Harbour and the Pearl River, South China using high-performance liquid chromatography-electrospray ionization tandem mass spectrometry, Environmental Pollution, Cilt. 145, s. 672–679. DOI: 10.1016/j.envpol.2006.05.038
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  • Kolpin, D.W., Furlong, E.T., Meyer, M.T. 2002. Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000:  A National Reconnaissance, Environmental Science and Technology, Cilt. 36, s. 1202–1211. DOI: 10.1021/es011055j
  • Diaz-Cruz, M.S., Barcelo D. 2005. LC–MS2 trace analysis of antimicrobials in water, sediment and soil, TrAC Trends in Analytical Chemistry, Cilt. 24, s. 645-657.DOI: 10.1016/j.trac.2005.05.005
  • Göbel, A. Thomsen A., McArdell, Joss, C.S., Giger,. A. 2005. Occurrence and Sorption Behavior of Sulfonamides, Macrolides, and Trimethoprim in Activated Sludge Treatment, Environmental Science and Technology, Cilt. 39, s. 3981–3989. DOI: 10.1021/es048550a
  • Kim S.C., Carlson, K. 2007. Temporal and Spatial Trends in the Occurrence of Human and Veterinary Antibiotics in Aqueous and River Sediment Matrices, Environmental Science and Technology, Cilt. 41, s. 50–57. DOI: 10.1021/es060737+
  • Fent, K., Weston, A.A., Caminada, D. 2006. Erratum to “Ecotoxicology of human pharmaceuticals”, Aquatic Toxicology, Cilt. 76, s. 122–159.DOI: 10.1016/j. aquatox. 2005.09. 009
  • Davison, J. 1999. Genetic exchange between bacteria in the environment, Plasmid, Cilt. 42, s. 73–91. DOI: 10.1006/plas.1999.1421
  • Florey, K. 1978. Analytical Profile of Drug Substances, 7th, ACADEMIC PRESS, New York, 459s.
  • Hitchings, G.H., Burchall, J.J. 1965. Advances in Enzymology, 27th, WILEY/INTERSCIENCE, New York, 417s.
  • Brindley, G.W., Kao, C.-C. 1980. Formation, compositions and properties of hyrdroxy-Al- and hydroxy-Mg-montmorillonite, Clay Clay Minerals, Cilt. 28, s. 435–443.
  • Pinnavaia, T.J. 1983. Intercalated clay catalysts, Science, Cilt. 220, s. 365–371. DOI: 10.1126/science.220.4595.365
  • Thomas, P.C., Velthovena, K., Geurtsa, M., Van Wijka, D. 2009. Bioavailability and detoxification of cationics: II. Relationship between toxicity and CEC of cationic surfactants on Caenorhabditis elegans (Nematoda) in artificial and natural substrates, Chemosphere, Cilt. 75, s. 310–318. DOI: 10.1016/j.chemosphere.2009.02.003
  • Sing, K.S.W., Everett, D.H., Haul, R.A.W., Moscou, L., Pierotti, R.A., Rouquerol, J., Siemieniewska, T. 1985. Pure Applied Chemistry, Cilt. 57, s. 603–619.
  • Olphen, H.V., Fripiat, J.J. 1979. Data Handbook for Clay Minerals and Other Non-Metallic Materials, PERGAMON PRESS, London.
  • Molu Bekçi, Z., Yurdakoç, K..2010. Preparation and characterization of aluminum pillared K10 and KSF for adsorption of trimethoprim, Microporous and Mesoporous Materials, Cilt. 127, s. 50–60. DOI: 10.1016/j.micromeso.2009.06.027
  • Manohar, D.M., Noeline, B.F., Anirudhan T.S. 2006. Adsorption performance of Al-pillared bentonite clay for the removal of cobalt(II) from aqueous phase, Applied Clay Science, Cilt. 31, s. 194–206. DOI: 10.1016/j.clay.2005.08.008
  • Lagergren, S. 1898. Zur theorie der sogenannten adsorption geïoster stoffe. Kunglinga Svenska Vetenskapsakademiens, Handlingar Cil:24, s. 1–39.
  • Ho, Y.S., McKay, G. 1999. Pseudo-second order model for sorption processes, Process Biochemistry Cilt. 34, s. 451–465. DOI: 10.1016/S0032-9592(98)00112-5
  • Bulut, Y., Aydın, H. 2006. A kinetics and thermodynamics study of methylene blue adsorption on wheat shells, Desalination, Cilt: 194, s. 259-267. DOI: 10.1016/j.desal.2005.10.032
  • Weber, W.J., Morris, J.C., Sanit, J. 1963. Kinetics of adsorption on carbon from solution, Eng. Div. ASCE, Cilt. 89, s. 31–59.
  • Özcan, A.S., Özcan, A. 2004. Adsorption of acid dyes from aqueous solutions onto acid-activated bentonite, Journal of Colloid Interface Science, Cilt. 276, s. 39–46. DOI: 10.1016/j.jcis.2004.03.043
  • Giles, C.H., McEvan, T.H., Nakhwa, S.N., Smith, D. 1960. A system of classification of solution adsorption isotherms, and its use in diagnosis of adsorption mechanisms and in measurement of specific surface areas, Journal of Chemical Society, Cilt. 4, s. 3973–3993.
  • Langmuir, I. 1918. The adsorption of gases on plane surfaces of glass, mica and platinum, Journal of the American Chemical society, Cilt. 40, s. 1361–1403. DOI: 10.1021/ja02242a004
  • Aksu,Z., Kabasakal, E. 2004. Batch adsorption of 2, 4-dichlorophenoxy-acetic acid (2, 4-D) from aqueous solution by granular activated carbon Separation and Purification Technology, Cilt. 35, s. 223–240. DOI:10.1016/S1383-5866(03)00144-8
  • Lin, S.H., Juang, R.S. 2002. Heavy metal removal from water by sorption using surfactant-modified montmorillonite, Journal of hazardous materials, Cilt. 92, s. 315–326. DOI: 10.1016/S0304-3894(02)00026-2
  • Dubinin, M.M., Radushkevich, L.V. 1947. The equation of the characteristic curve of activated charcoal, Proc. Acad. Sci. USSR, Cilt. 55, s. 331–333.
  • Singh, T.S., Pant, K.K. 2004. Equilibrium, kinetics and thermodynamic studies for adsorption of As (III) on activated alumina, Separation and purification technology, Cilt. 36, s. 139–147. DOI: 10.1016/S1383-5866(03)00209-0
  • Narine, D.R., Guy, R.D. 1981. Interactions of some large organic cations with bentonite in dilute aqueous systems, Clays Clay Minerals, Cilt. 29, s. 205–212.
  • Nollet, H., Roels, M., Lutgen, P., Van der Meeren, P., Verstraete, W. 2003. Removal of PCBs from wastewater using fly ash, Chemosphere, Cilt. 53, s. 655-665. DOI: 10.1016/S0045-6535(03)00517-4
  • Liu, H., Zhang, J., Bao, N., Cheng, C., Ren, L., Zhang, C. 2012. Textural properties and surface chemistry of lotus stalk-derived activated carbons prepared using different phosphorus oxyacids: Adsorption of trimethoprim, Journal of Hazardous Materials, Cilt. 235– 236, s. 367– 375. DOI: 10.1016/j.jhazmat.2012.08.015
  • Kim, S.H., Shon, H.K., Ngo, H.H. 2010. Adsorption characteristics of antibiotics trimethoprim on powdered and granular activated carbon, Journal of Industrial and Engineering Chemistry, Cilt. 16, s. 344–349. DOI: 10.1016/j.jiec.2009.09.061
  • Gonzalez, B., H. da Silva , T., Ciuffi, K. J. , Vicente, M. A., Trujillano, R., Rives, V., de Faria, E. H., Korili, S. A., Gil, A. 2017. Laponite functionalized with biuret and melamine- Application to adsorption of antibiotic trimethoprim, Microporous and Mesoporous Materials, Cilt. 253, s. 112-122. DOI: 10.1016/j.micromeso.2017.06.047
  • Salihi, E. Ç., Mahramanlıoğlu, M. 2014. Equilibrium and kinetic adsorption of drugs on bentonite: Presence of surface active agents effect, Applied Clay Science, Cilt. 101, s. 381–389. DOI: 10.1016/j.clay.2014.06.015
  • Nielsen, L., Bandosz, T.J. 2016. Analysis of sulfamethoxazole and trimethoprim adsorption on sewage sludge and fish waste derived adsorbents, Microporous Mesoporous Materials, Cilt. 220, s. 58-72. DOI: 10.1016/j.micromeso. 2015.08.025.

Year 2020, Volume: 22 Issue: 66, 949 - 963, 22.09.2020

Zehra Molu

https://doi.org/10.21205/deufmd.2020226628

Abstract

References

  • Lindsey, M.E., Meyer, M., Thurman, E.M. 2001. Analysis of Trace Levels of Sulfonamide and Tetracycline Antimicrobials in Groundwater and Surface Water Using Solid-Phase Extraction and Liquid Chromatography/Mass Spectrometry, Analytical Chemistry,Cilt. 15, s. 4640–4646. DOI: 10.1021/ac010514w
  • Xu, W., Zhang, G., Zou S., Li, X., Liu Y. 2007. Determination of selected antibiotics in the Victoria Harbour and the Pearl River, South China using high-performance liquid chromatography-electrospray ionization tandem mass spectrometry, Environmental Pollution, Cilt. 145, s. 672–679. DOI: 10.1016/j.envpol.2006.05.038
  • Gulkowska, A., He, Y., So, M.K., Yeung, L.W.Y., Leung, H. W., Giesy, J.P., Lam,P.K.S., Martin, M., Richardson, B.J. 2007. Marine pollution bulletin, Cilt. 54, s. 1287–1293.DOI: 10.1016/j.marpolbul.2007.04.008
  • Kolpin, D.W., Furlong, E.T., Meyer, M.T. 2002. Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000:  A National Reconnaissance, Environmental Science and Technology, Cilt. 36, s. 1202–1211. DOI: 10.1021/es011055j
  • Diaz-Cruz, M.S., Barcelo D. 2005. LC–MS2 trace analysis of antimicrobials in water, sediment and soil, TrAC Trends in Analytical Chemistry, Cilt. 24, s. 645-657.DOI: 10.1016/j.trac.2005.05.005
  • Göbel, A. Thomsen A., McArdell, Joss, C.S., Giger,. A. 2005. Occurrence and Sorption Behavior of Sulfonamides, Macrolides, and Trimethoprim in Activated Sludge Treatment, Environmental Science and Technology, Cilt. 39, s. 3981–3989. DOI: 10.1021/es048550a
  • Kim S.C., Carlson, K. 2007. Temporal and Spatial Trends in the Occurrence of Human and Veterinary Antibiotics in Aqueous and River Sediment Matrices, Environmental Science and Technology, Cilt. 41, s. 50–57. DOI: 10.1021/es060737+
  • Fent, K., Weston, A.A., Caminada, D. 2006. Erratum to “Ecotoxicology of human pharmaceuticals”, Aquatic Toxicology, Cilt. 76, s. 122–159.DOI: 10.1016/j. aquatox. 2005.09. 009
  • Davison, J. 1999. Genetic exchange between bacteria in the environment, Plasmid, Cilt. 42, s. 73–91. DOI: 10.1006/plas.1999.1421
  • Florey, K. 1978. Analytical Profile of Drug Substances, 7th, ACADEMIC PRESS, New York, 459s.
  • Hitchings, G.H., Burchall, J.J. 1965. Advances in Enzymology, 27th, WILEY/INTERSCIENCE, New York, 417s.
  • Brindley, G.W., Kao, C.-C. 1980. Formation, compositions and properties of hyrdroxy-Al- and hydroxy-Mg-montmorillonite, Clay Clay Minerals, Cilt. 28, s. 435–443.
  • Pinnavaia, T.J. 1983. Intercalated clay catalysts, Science, Cilt. 220, s. 365–371. DOI: 10.1126/science.220.4595.365
  • Thomas, P.C., Velthovena, K., Geurtsa, M., Van Wijka, D. 2009. Bioavailability and detoxification of cationics: II. Relationship between toxicity and CEC of cationic surfactants on Caenorhabditis elegans (Nematoda) in artificial and natural substrates, Chemosphere, Cilt. 75, s. 310–318. DOI: 10.1016/j.chemosphere.2009.02.003
  • Sing, K.S.W., Everett, D.H., Haul, R.A.W., Moscou, L., Pierotti, R.A., Rouquerol, J., Siemieniewska, T. 1985. Pure Applied Chemistry, Cilt. 57, s. 603–619.
  • Olphen, H.V., Fripiat, J.J. 1979. Data Handbook for Clay Minerals and Other Non-Metallic Materials, PERGAMON PRESS, London.
  • Molu Bekçi, Z., Yurdakoç, K..2010. Preparation and characterization of aluminum pillared K10 and KSF for adsorption of trimethoprim, Microporous and Mesoporous Materials, Cilt. 127, s. 50–60. DOI: 10.1016/j.micromeso.2009.06.027
  • Manohar, D.M., Noeline, B.F., Anirudhan T.S. 2006. Adsorption performance of Al-pillared bentonite clay for the removal of cobalt(II) from aqueous phase, Applied Clay Science, Cilt. 31, s. 194–206. DOI: 10.1016/j.clay.2005.08.008
  • Lagergren, S. 1898. Zur theorie der sogenannten adsorption geïoster stoffe. Kunglinga Svenska Vetenskapsakademiens, Handlingar Cil:24, s. 1–39.
  • Ho, Y.S., McKay, G. 1999. Pseudo-second order model for sorption processes, Process Biochemistry Cilt. 34, s. 451–465. DOI: 10.1016/S0032-9592(98)00112-5
  • Bulut, Y., Aydın, H. 2006. A kinetics and thermodynamics study of methylene blue adsorption on wheat shells, Desalination, Cilt: 194, s. 259-267. DOI: 10.1016/j.desal.2005.10.032
  • Weber, W.J., Morris, J.C., Sanit, J. 1963. Kinetics of adsorption on carbon from solution, Eng. Div. ASCE, Cilt. 89, s. 31–59.
  • Özcan, A.S., Özcan, A. 2004. Adsorption of acid dyes from aqueous solutions onto acid-activated bentonite, Journal of Colloid Interface Science, Cilt. 276, s. 39–46. DOI: 10.1016/j.jcis.2004.03.043
  • Giles, C.H., McEvan, T.H., Nakhwa, S.N., Smith, D. 1960. A system of classification of solution adsorption isotherms, and its use in diagnosis of adsorption mechanisms and in measurement of specific surface areas, Journal of Chemical Society, Cilt. 4, s. 3973–3993.
  • Langmuir, I. 1918. The adsorption of gases on plane surfaces of glass, mica and platinum, Journal of the American Chemical society, Cilt. 40, s. 1361–1403. DOI: 10.1021/ja02242a004
  • Aksu,Z., Kabasakal, E. 2004. Batch adsorption of 2, 4-dichlorophenoxy-acetic acid (2, 4-D) from aqueous solution by granular activated carbon Separation and Purification Technology, Cilt. 35, s. 223–240. DOI:10.1016/S1383-5866(03)00144-8
  • Lin, S.H., Juang, R.S. 2002. Heavy metal removal from water by sorption using surfactant-modified montmorillonite, Journal of hazardous materials, Cilt. 92, s. 315–326. DOI: 10.1016/S0304-3894(02)00026-2
  • Dubinin, M.M., Radushkevich, L.V. 1947. The equation of the characteristic curve of activated charcoal, Proc. Acad. Sci. USSR, Cilt. 55, s. 331–333.
  • Singh, T.S., Pant, K.K. 2004. Equilibrium, kinetics and thermodynamic studies for adsorption of As (III) on activated alumina, Separation and purification technology, Cilt. 36, s. 139–147. DOI: 10.1016/S1383-5866(03)00209-0
  • Narine, D.R., Guy, R.D. 1981. Interactions of some large organic cations with bentonite in dilute aqueous systems, Clays Clay Minerals, Cilt. 29, s. 205–212.
  • Nollet, H., Roels, M., Lutgen, P., Van der Meeren, P., Verstraete, W. 2003. Removal of PCBs from wastewater using fly ash, Chemosphere, Cilt. 53, s. 655-665. DOI: 10.1016/S0045-6535(03)00517-4
  • Liu, H., Zhang, J., Bao, N., Cheng, C., Ren, L., Zhang, C. 2012. Textural properties and surface chemistry of lotus stalk-derived activated carbons prepared using different phosphorus oxyacids: Adsorption of trimethoprim, Journal of Hazardous Materials, Cilt. 235– 236, s. 367– 375. DOI: 10.1016/j.jhazmat.2012.08.015
  • Kim, S.H., Shon, H.K., Ngo, H.H. 2010. Adsorption characteristics of antibiotics trimethoprim on powdered and granular activated carbon, Journal of Industrial and Engineering Chemistry, Cilt. 16, s. 344–349. DOI: 10.1016/j.jiec.2009.09.061
  • Gonzalez, B., H. da Silva , T., Ciuffi, K. J. , Vicente, M. A., Trujillano, R., Rives, V., de Faria, E. H., Korili, S. A., Gil, A. 2017. Laponite functionalized with biuret and melamine- Application to adsorption of antibiotic trimethoprim, Microporous and Mesoporous Materials, Cilt. 253, s. 112-122. DOI: 10.1016/j.micromeso.2017.06.047
  • Salihi, E. Ç., Mahramanlıoğlu, M. 2014. Equilibrium and kinetic adsorption of drugs on bentonite: Presence of surface active agents effect, Applied Clay Science, Cilt. 101, s. 381–389. DOI: 10.1016/j.clay.2014.06.015
  • Nielsen, L., Bandosz, T.J. 2016. Analysis of sulfamethoxazole and trimethoprim adsorption on sewage sludge and fish waste derived adsorbents, Microporous Mesoporous Materials, Cilt. 220, s. 58-72. DOI: 10.1016/j.micromeso. 2015.08.025.
There are 36 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Zehra Molu 0000-0003-2393-9160

Publication Date September 22, 2020
Published in Issue Year 2020 Volume: 22 Issue: 66

Cite

APA Molu, Z. (2020). Bir Antibiyotik olan Trimetoprimin Sütunlu Kil ile Sulu Ortamdan Uzaklaştırılması. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen Ve Mühendislik Dergisi, 22(66), 949-963. https://doi.org/10.21205/deufmd.2020226628
AMA Molu Z. Bir Antibiyotik olan Trimetoprimin Sütunlu Kil ile Sulu Ortamdan Uzaklaştırılması. DEUFMD. September 2020;22(66):949-963. doi:10.21205/deufmd.2020226628
Chicago Molu, Zehra. “Bir Antibiyotik Olan Trimetoprimin Sütunlu Kil Ile Sulu Ortamdan Uzaklaştırılması”. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen Ve Mühendislik Dergisi 22, no. 66 (September 2020): 949-63. https://doi.org/10.21205/deufmd.2020226628.
EndNote Molu Z (September 1, 2020) Bir Antibiyotik olan Trimetoprimin Sütunlu Kil ile Sulu Ortamdan Uzaklaştırılması. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen ve Mühendislik Dergisi 22 66 949–963.
IEEE Z. Molu, “Bir Antibiyotik olan Trimetoprimin Sütunlu Kil ile Sulu Ortamdan Uzaklaştırılması”, DEUFMD, vol. 22, no. 66, pp. 949–963, 2020, doi: 10.21205/deufmd.2020226628.
ISNAD Molu, Zehra. “Bir Antibiyotik Olan Trimetoprimin Sütunlu Kil Ile Sulu Ortamdan Uzaklaştırılması”. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen ve Mühendislik Dergisi 22/66 (September 2020), 949-963. https://doi.org/10.21205/deufmd.2020226628.
JAMA Molu Z. Bir Antibiyotik olan Trimetoprimin Sütunlu Kil ile Sulu Ortamdan Uzaklaştırılması. DEUFMD. 2020;22:949–963.
MLA Molu, Zehra. “Bir Antibiyotik Olan Trimetoprimin Sütunlu Kil Ile Sulu Ortamdan Uzaklaştırılması”. Dokuz Eylül Üniversitesi Mühendislik Fakültesi Fen Ve Mühendislik Dergisi, vol. 22, no. 66, 2020, pp. 949-63, doi:10.21205/deufmd.2020226628.
Vancouver Molu Z. Bir Antibiyotik olan Trimetoprimin Sütunlu Kil ile Sulu Ortamdan Uzaklaştırılması. DEUFMD. 2020;22(66):949-63.

Dokuz Eylül Üniversitesi, Mühendislik Fakültesi Dekanlığı Tınaztepe Yerleşkesi, Adatepe Mah. Doğuş Cad. No: 207-I / 35390 Buca-İZMİR.