Biological Activities of Extracts of Gmelina asiatica L.

Year 2022, Volume: 5 Issue: 1, 1 - 13, 21.10.2022

Vinujan Shanmugalingam , Saravanan Vivekanandarajah Sathasivampillai , Pholtan Rajeev Sebastian

Abstract

Gmelina asiatica L. is a shrub that belongs to the Lamiaceae family. In various traditional medicines, this plant species is employed to cure several disorders like rheumatism, gonorrhea, catarrh of the bladder, edema, and malaria. Furthermore, phytochemicals including cleomeolide; cleomiscosin D; kaempferide-3-glucuronide; nitidine; ovalifolin; and stigmasta-5, 24(28)-diene-3-O-rhamnoside were detected from different parts of G. asiatica. This paper aims to evaluate, summarize, and document the published biological activities related to investigations of G. asiatica. SpringerLink, Semantic Scholar, Scopus, ScienceDirect, Taylor & Francis Online, Wiley Online Library, Sage journals, Mary Ann Liebert, Inc. Publishers, PubMed, and Web of Science databases were used to identify the relevant published articles from 1900 to August 2021. Up to now, only in vivo and in vitro scientific evidence are present for various bioactivities. In addition, anti-anxiety, antibacterial, anticancer, antidandruff, antidiabetic, antifungal, anti-inflammatory, antioxidant, antipyretic, hepatoprotective, and nephroprotective activities were detected for various parts of this plant. This article will be advantageous to carry out support further biological activity investigations of this plant in the future.

Keywords

Antibacterial, Bioactivity, Gmelina asiatica, Lamiaceae, Siddha Medicine, Sri Lanka

Supporting Institution

Not applicable

Project Number

Not applicable

Thanks

The authors appreciative their family members for the support to deliver this work.

Gmelina asiatica L. Ekstraktlarının Biyolojik Aktiviteleri

Abstract

Gmelina asiatica L., Lamiaceae familyasına ait bir çalıdır. Çeşitli geleneksel ilaçlarda bu bitki türü, romatizma, bel soğukluğu, mesane nezlesi, ödem ve sıtma gibi çeşitli rahatsızlıkları tedavi etmek için kullanılır. Ayrıca, kleomeolid dahil fitokimyasallar; kleomiskosin D; kaempferid-3-glukuronid; nitidin; ovalifolin; ve stigmasta-5, 24(28)-diene-3-O-rhamnoside, G. asiatica'nın farklı bölümlerinden tespit edildi. Bu makale, G. asiatica araştırmalarıyla ilgili yayınlanmış biyolojik aktiviteleri değerlendirmeyi, özetlemeyi ve belgelemeyi amaçlamaktadır. SpringerLink, Semantic Scholar, Scopus, ScienceDirect, Taylor & Francis Online, Wiley Online Library, Sage dergileri, Mary Ann Liebert, Inc. Publishers, PubMed ve Web of Science veri tabanları, 1900'den Ağustos 2021'e kadar ilgili yayınlanmış makaleleri belirlemek için kullanıldı. Şimdiye kadar, çeşitli biyoaktiviteler için sadece in vivo ve in vitro bilimsel kanıtlar mevcuttur. Ayrıca bu bitkinin çeşitli kısımları için anti-anksiyete, antibakteriyel, antikanser, kepek önleyici, diyabetik, mantar önleyici, iltihap önleyici, antioksidan, ateş düşürücü, hepatoprotektif ve nefroprotektif aktiviteler tespit edilmiştir. Bu makale, gelecekte bu bitkinin biyolojik aktivite araştırmalarını desteklemek için avantajlı olacaktır.

Keywords

Antibakteriyel, biyoaktivite, Gmelina asiatica, Lamiaceae, Siddha Tıbbı, Sri Lanka

Project Number

Not applicable

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