Comparison of Optic Coherence Tomography Findings of Chronic Renal Failure and Renal Transplant Patients

Abstract

Comparison of Optic Coherence Tomography Findings of Chronic Renal Failure and Renal Transplant Patients

Abstract

Objective: To compare the Spectral-Domain Optic Coherence Tomography (SD-OCT) findings of chronic renal failure (CRF) and renal transplant (RTx) patients. Methods: Sixty eyes of thirty patients with CRF and 60 eyes of thirty RTx patients were enrolled in the study. A thorough ophthalmologic examination was applied to each patient, including the following parameters: best-corrected visual acuity (BCVA), intraocular pressure (IOP), anterior and posterior segment examination, central corneal thickness (CCT), retinal nerve fiber layer thickness (RNFLT), foveal thickness (FT), and choroid thickness (ChT) measurements. Results: Distribution of the primary disease, gender and the median duration of RTx and CRF (18 and 36 months respectively, p=0.390) were similar between the groups, and the difference was not significant. The mean age of patients in the CRF group was statistically higher than that of the RTx group (57.5±10.6 and 44.4±11.9 years respectively, p<0.001). There was no statistically significant difference in terms of BCVA, IOP, CCT, FT, and ChT values between the groups. Left C/D ratios in the left eye of RTx group were significantly higher than the CRF group (0.401±0.031 and 0.342 ±0.027 respectively, p=0.035). Temporal inferior (TI) RNFLT values in the left eye of RTx group were significantly higher than the CRF group (144.76±4.24μm and 135.09±3.91μm respectively, p=0.005) Conclusion: There was no remarkable difference in SD-OCT findings between the two groups, except the significantly higher RNFLT (TI) values in left eye of RTx patients. The result of our study shows that renal transplantation might have a positive effect on retinal morphology and retinal functions. Our results should be supported with further studies.

Keywords

• choroid thickness
• foveal thickness; renal failure
• renal transplantation; retinal nerve fiber layer thickness

References

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