Examination of Radiological Findings and Clinical Parameters in Paediatric Patients with Covid-19

Year 2023, , 354 - 364, 15.09.2023

Zeynep Ece Tastekin Polat Kamil Yılmaz , Mehmet Turmak

https://doi.org/10.5798/dicletip.1360679

Abstract

Objective: It was aimed to evaluate the relationship between imaging techniques and clinical and laboratory parameters in paediatric COVID-19 patients.
Methods: Our study included 187 patients under the age of 18 whose diagnosis of COVID-19 was confirmed by PCR test. Demographic, clinical, laboratory and radiological imaging findings of the patients were reviewed retrospectively from their file records.
Results: 57.2% of the patients were male and the mean age was 110.1±67.4 months. A pulmonary finding associated with COVID-19 was detected in 21 (12%) of 175 patients who underwent Posterior-anterior (PA) chest X-ray. The most common findings were consolidation (n=16; 9.1%), bilateral ground-glass appearance (n=11; 6.3%), and atelectasis (n=5; 2.9%), respectively. Computed lung tomography was performed in 67 of the patients. The presence of a pulmonary finding associated with COVID-19 was detected in 28 (41.8%) of these patients. The three most common findings were consolidation (n=16; 23.9%), bilateral ground glass appearance (n=16; 23.9%), and atelectasis (n=15; 22.4%), respectively. It was determined that for patients with imaging findings on PA X-ray needed more paediatric intensive care, the length of their hospital stay was longer, comorbid diseases were present, their cough and tachypnea complaints were more pronounced (p<0.05). As the disease severity increased, especially in patients <1 year of age, the frequency of significant findings increased in both imaging methods (p<0.05).
Conclusion: We think that imaging methods can be performed when necessary in children with suspected COVID-19 and can provide preliminary information about the course and severity of the disease.

Keywords

Computed Tomography, COVID-19, Paediatrics, Radiological findings, X ray

References

• 1.Khan W, Coronavirus disease 2019 (covid-19).Journal of Saidu Medical College, Swat. 2020;10.
• 2.Dong Y, X Mo, Y Hu, et al. Epidemiology of COVID-19 Among Children in China. Pediatrics. 2020;145.
• 3.de Lusignan S, J Dorward, A Correa, et al. Riskfactors for SARS-CoV-2 among patients in the Oxford Royal College of General Practitioners Research andSurveillance Centre primary care network: a cross-sectional study. Lancet Infect Dis. 2020;20:1034-42.
• 4.Adeyinka A, K Bailey, L Pierre, et al. COVID 19infection: Pediatric perspectives. Journal of theAmerican College of Emergency Physicians Open.2021;2:e12375.
• 5.Cui X, Zhao Z, Zhang T, et al. A systematic reviewand meta-analysis of children with coronavirusdisease 2019 (COVID-19). J Med Virol.2021;93(2):1057-1069.
• 6.Laws RL, RJ Chancey, EM Rabold, et al. Symptomsand Transmission of SARS-CoV-2 Among Children -Utah and Wisconsin, March-May 2020. Pediatrics.2021;147.
• 7.Götzinger F, B Santiago-García, A Noguera-Julián,et al. COVID-19 in children and adolescents inEurope: a multinational, multicentre cohort study.Lancet Child Adolesc Health. 2020;4:653-61.
• 8.Stewart DJ, JC Hartley, M Johnson, et al. Renaldysfunction in hospitalised children with COVID-19.Lancet Child Adolesc Health. 2020;4:e28-e29.
• 9.Nino G, J Zember, R Sanchez-Jacob, et al. Pediatriclung imaging features of COVID-19: A systematicreview and meta-analysis. 2021;56:252-63.
• 10.Shen K, Y Yang, T Wang, et al. Diagnosis,treatment, and prevention of 2019 novelcoronavirus infection in children: experts’consensus statement. World journal of pediatrics.2020;16:223-31.
• 11.Salehi S, A Abedi, S Balakrishnan, et al.Coronavirus disease 2019 (COVID-19): a systematicreview of imaging findings in 919 patients. Ajr Am JRoentgenol. 2020;215:87-93.
• 12.Liguoro I, C Pilotto, M Bonanni, et al. SARS-COV-2 infection in children and newborns: a systematicreview. European journal of pediatrics.2020;179:1029-46.
• 13. Erat T, Ş Güler, Use of radiological tests in COVID‐19 positive child cases: Is chest computedtomography necessary? International journal ofclinical practice. 2021;75:e14259.
• 14.Bayramoglu Z, E Canıpek, RG Comert, et al.Imaging features of pediatric COVID-19 on chestradiography and chest CT: a retrospective, single-center study. Academic radiology. 2021;28:18-27.
• 15.Lu X, L Zhang, H Du, et al. SARS-CoV-2 infectionin children. New England Journal of Medicine.2020;382:1663-5.
• 16.Mohammadi A, I Mohebbi, H Pirnejad, et al.Clinical and radiological characteristics of pediatricpatients with COVID-19: focus on imaging findings.Japanese Journal of Radiology. 2020;38:987-92.
• 17.Palabiyik F, SO Kokurcan, N Hatipoglu, et al.Imaging of COVID-19 pneumonia in children. TheBritish journal of radiology. 2020;93:20200647.
• 18.Bellino S, O Punzo, MC Rota, et al. COVID-19disease severity risk factors for pediatric patients inItaly. Pediatrics. 2020;146.
• 19.Hoang A, K Chorath, A Moreira, et al. COVID-19 in 7780 pediatric patients: a systematic review.EClinicalMedicine. 2020;24:100433.
• 20.Katal S, SK Johnston, JH Johnston, et al. Imagingfindings of SARS-CoV-2 infection in pediatrics: asystematic review of coronavirus disease 2019(COVID-19) in 850 patients. Academic Radiology.2020;27:1608-1621.
• 21.Ma H, J Hu, J Tian, et al. A single-center,retrospective study of COVID-19 features inchildren: a descriptive investigation. BMC Medicine.2020;18:123.
• 22.Cura Yayla BC, Y Özsürekçi, K Aykaç, et al.Characteristics and Management of Children withCOVID-19 in Turkey. Balkan Med J. 2020;37:341-7.
• 23. Velat, Ş. E. N., & Hasan, Z. A. N. (2021). ÇocuklardaCOVİD-19 ve Yoğun Bakım Yönetimi. Dicle TıpDergisi, 48, 154-65.