Impact of high triglyceride/high-density lipoprotein cholesterol ratio in non-st segment elevation myocardial infarction

Year 2024, , 351 - 359, 19.09.2024

Süleyman Akkaya , Kaya Özen

https://doi.org/10.5798/dicletip.1552487

Abstract

Introductıon: Globally, cardiovascular disease (CVD) is the leading cause of death. Among these risk factors, dyslipidemia, hypertension, and diabetes mellitus (DM) are significant pathological disorders that lead to this illness. In addition to being a risk factor for cardiovascular disease, insulin resistance is a prevalent characteristic of metabolic syndrome, obesity, and diabetes mellitus. It has been demonstrated that the triglyceride/HDL ratio is a valid indicator of insulin resistance.
In this study, we tried to emphasize the criticality of early intervention in NSTEMI patients by revealing whether the TG/HDL ratio indicating insulin resistance is different between NSTEMI and ST elevation myocardial infarction (STEMI) patients.
Methods: Patients admitted to a training and research hospital with a prediagnosis of acute coronary syndrome and diagnosed as having NSTEMI or STEMI were included in the study. Our study included 113 NSTEMI and 166 STEMI patients.
Results: In NSTEMI patients, the mean HDL value was 39 (25-65) mg/dl, the mean LDL value was 105 (29-244) mg/dl, the mean T. cholesterol value was 180 (78-356) mg/dl, and the mean triglyceride value was 136 (37-360) mg/dl. When NSTEMI patients were compared with STEMI patients in terms of TG/HDL ratio, NSTEMI patients were significantly higher. (p:0.027; p<0.005).
Conclusıon: Increased TG/HDL ratios are one measure of insulin resistance. The TG/HDL ratio is elevated in NSTEMI patients, according to our research. Therefore, we can help reduce morbidity and mortality by planning early intervention in NSTEMI patients with high TG/HDL ratios.

Keywords

acute coronary syndrome, Non-ST segment elevation myocardial infarction, ST elevation myocardial infarction, Triglyceride, high density lipoprotein

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