The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis

Semih Hot; Nüvit Duraker; Ayhan Sarı; Kenan Çetin

doi:10.5798/diclemedj.0921.2016.01.0644

The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis

Abstract

Objective: Because of its poor prognosis and high mortality rate, early diagnosis of acute mesenteric ischemia (AMI) is a challenge. The value of serum markers in the diagnosis of AMI is limited and the studies related with the D-dimer test carried out in recent years. In this prospective study we investigated the value of the level of plasma D-dimer in the diagnosis of AMI and the differential diagnosis from acute pancreatitis and acute cholecystitis.
Methods: We included 89 patients who admitted to our emergency department with abdominal pain. The number and the diagnosis of the patients were 17 AMI, 42 acute pancreatitis and 30 acute cholecystitis, respectively. We measured the levels of plasma D-dimer of all patients by using a latex agglutination ‘immunoassay’ method. Eventually we calculated the sensitivity and specificity of D-dimer test in the diagnosis of AMI.
Results: We determined the specificity of the D-dimer test in the differential diagnosis of AMI as 50% from acute pancreatitis, 70% from acute cholecystitis, 58.3% from all the control group and the sensitivity was 100%.
Conclusion: The measurement of plasma D-dimer concentration may be useful in the differential diagnosis of AMI from acute pancreatitis and acute cholecystitis. However, to reveal the diagnostic value of D-dimer test more clearly, further studies with larger series are needed, where cut-off value is highly defined, and other patients with acute abdominal pain are added into the control group.
Key words: Acute mesenteric ischemia, diagnosis, D-dimer

Keywords

Akut mezenterik iskemi, tanı, D-dimer

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Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Semih Hot This is me

Nüvit Duraker This is me

Ayhan Sarı This is me

Kenan Çetin This is me

Publication Date

March 1, 2016

Submission Date

March 29, 2016

Acceptance Date

-

Published in Issue

Year 2016 Volume: 43 Number: 1

DOI

https://doi.org/10.5798/diclemedj.0921.2016.01.0644

IZ

https://izlik.org/JA92LG93SW

Cite

RIS / Bibtex

APA

Hot, S., Duraker, N., Sarı, A., & Çetin, K. (2016). The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis. Dicle Medical Journal, 43(1), 88-92. https://doi.org/10.5798/diclemedj.0921.2016.01.0644

AMA

1.Hot S, Duraker N, Sarı A, Çetin K. The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis. Dicle Medical Journal. 2016;43(1):88-92. doi:10.5798/diclemedj.0921.2016.01.0644

Chicago

Hot, Semih, Nüvit Duraker, Ayhan Sarı, and Kenan Çetin. 2016. “The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis”. Dicle Medical Journal 43 (1): 88-92. https://doi.org/10.5798/diclemedj.0921.2016.01.0644.

EndNote

Hot S, Duraker N, Sarı A, Çetin K (March 1, 2016) The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis. Dicle Medical Journal 43 1 88–92.

IEEE

[1]S. Hot, N. Duraker, A. Sarı, and K. Çetin, “The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis”, Dicle Medical Journal, vol. 43, no. 1, pp. 88–92, Mar. 2016, doi: 10.5798/diclemedj.0921.2016.01.0644.

ISNAD

Hot, Semih - Duraker, Nüvit - Sarı, Ayhan - Çetin, Kenan. “The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis”. Dicle Medical Journal 43/1 (March 1, 2016): 88-92. https://doi.org/10.5798/diclemedj.0921.2016.01.0644.

JAMA

1.Hot S, Duraker N, Sarı A, Çetin K. The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis. Dicle Medical Journal. 2016;43:88–92.

MLA

Hot, Semih, et al. “The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis”. Dicle Medical Journal, vol. 43, no. 1, Mar. 2016, pp. 88-92, doi:10.5798/diclemedj.0921.2016.01.0644.

Vancouver

1.Semih Hot, Nüvit Duraker, Ayhan Sarı, Kenan Çetin. The Value of D-Dimer in Diagnosis of Acute Mesenteric Ischemia and Differential Diagnosis from Acute Pancreatitis and Acute Cholecystitis. Dicle Medical Journal. 2016 Mar. 1;43(1):88-92. doi:10.5798/diclemedj.0921.2016.01.0644