Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients with Schizophrenia

Fethullah Gerin; Aybala Toprak; Hayriye Erman; Sadettin Dürüyen; Alper Baş

doi:10.5798/diclemedj.0921.2016.01.0645

Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients with Schizophrenia

Abstract

Objective: We have investigated serum growth arrest-specific protein 6 (GAS-6) levels from patients with schizophrenia divided into acute phase remission phases as well as control group.
Methods: This study was conducted in Psychiatry Department of Istanbul University Cerrahpasa Medical Faculty. The patients who were diagnosed with schizophrenia after regular psychiatric examination according to DSM-IV criteria (n=22) as well as control subjects were included in the study. Schizophrenia patients with acute phase and remission phase were evaluated by Positive and Negative Syndrome Scale (PANSS) and Clinical global Impression Scale (CGI-S). The serum GAS-6 levels of schizophrenia patients during acute phase and remission phase were compared with the serum GAS-6 levels of healthy controls. Serum GAS-6 levels were measured by commercial ELISA kits.
Results: No difference was found in serum GAS-6 levels among the three groups; schizophrenia with acute phase, schizophrenia with remission phase, and controls. There were no correlations between serum GAS-6 levels and PANSS and CGI scores.
Conclusion: To reach a definitive data and better interpretation about the relationship between GAS-6 and schizophrenia, future studies with larger groups of patients with schizophrenia subdivided by drug naïve and treated with antipsychotics/other treatment modalities and controls are needed.
Key words: GAS-6, schizophrenia, acute phase, remission

Keywords

GAS-6, şizofreni, remisyon, akut atak

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Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Fethullah Gerin

Aybala Toprak This is me

Hayriye Erman This is me

Sadettin Dürüyen This is me

Alper Baş This is me

Publication Date

March 1, 2016

Submission Date

March 29, 2016

Acceptance Date

-

Published in Issue

Year 2016 Volume: 43 Number: 1

DOI

https://doi.org/10.5798/diclemedj.0921.2016.01.0645

IZ

https://izlik.org/JA95GF72GY

Cite

RIS / Bibtex

APA

Gerin, F., Toprak, A., Erman, H., Dürüyen, S., & Baş, A. (2016). Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients with Schizophrenia. Dicle Medical Journal, 43(1), 93-98. https://doi.org/10.5798/diclemedj.0921.2016.01.0645

AMA

1.Gerin F, Toprak A, Erman H, Dürüyen S, Baş A. Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients with Schizophrenia. Dicle Medical Journal. 2016;43(1):93-98. doi:10.5798/diclemedj.0921.2016.01.0645

Chicago

Gerin, Fethullah, Aybala Toprak, Hayriye Erman, Sadettin Dürüyen, and Alper Baş. 2016. “Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients With Schizophrenia”. Dicle Medical Journal 43 (1): 93-98. https://doi.org/10.5798/diclemedj.0921.2016.01.0645.

EndNote

Gerin F, Toprak A, Erman H, Dürüyen S, Baş A (March 1, 2016) Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients with Schizophrenia. Dicle Medical Journal 43 1 93–98.

IEEE

[1]F. Gerin, A. Toprak, H. Erman, S. Dürüyen, and A. Baş, “Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients with Schizophrenia”, Dicle Medical Journal, vol. 43, no. 1, pp. 93–98, Mar. 2016, doi: 10.5798/diclemedj.0921.2016.01.0645.

ISNAD

Gerin, Fethullah - Toprak, Aybala - Erman, Hayriye - Dürüyen, Sadettin - Baş, Alper. “Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients With Schizophrenia”. Dicle Medical Journal 43/1 (March 1, 2016): 93-98. https://doi.org/10.5798/diclemedj.0921.2016.01.0645.

JAMA

1.Gerin F, Toprak A, Erman H, Dürüyen S, Baş A. Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients with Schizophrenia. Dicle Medical Journal. 2016;43:93–98.

MLA

Gerin, Fethullah, et al. “Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients With Schizophrenia”. Dicle Medical Journal, vol. 43, no. 1, Mar. 2016, pp. 93-98, doi:10.5798/diclemedj.0921.2016.01.0645.

Vancouver

1.Fethullah Gerin, Aybala Toprak, Hayriye Erman, Sadettin Dürüyen, Alper Baş. Serum Growth Arrest Specific Protein 6 (Gas-6) Levels in Patients with Schizophrenia. Dicle Medical Journal. 2016 Mar. 1;43(1):93-8. doi:10.5798/diclemedj.0921.2016.01.0645