The most common cause of non-functioning kidney nephrectomy: Urolithiasis

Abstract

Objective: Our aim is to evaluate and present the characteristics of patients underwent nephrectomy due to non-functional kidney secondary to urolithiasis in our clinic. Methods: Totally 696 patients were anlyzed retrospectively who underwent nephrectomy in our clinic between January 2000 and December 2012. Etiologies and characteristics of nephrectomy applied patients due to non-tumoral non-functional kidney related with urinary tract stones are evaluated. Diagnoses of the patients were confirmed by using urinary system ultrasonography, abdominal computed tomography, intravenous urography and renal scintigraphy. Results: Nephrectomy was performed for 280 (40.2%) patients due to tumor formation and for 416 (59.8%) patients due to non-functional kidney of totally 696 patients. 43.8% (182) of non-funtional kidney cases were resulted by upper urinary tract stones. Mean age of nephrectomy performed urolithiasis patients were 43.7±16.9 years. 53.3% (97) of patients were male and 46.7% (85) patients were female. Preoperative mean creatinine value of patients were detected 2.98±0.47 mg/dl. Renal stone localizatian was ureteropelvic junction in 81.3% (148), ureter in 14.3% (26) and renal+ureter in 4.4% (8) of the patients. 66.8% of ureteropelvic junction stones were 10-30 mm in size. Conclusion: Upper urinary tract stones are primer responsible of non-functional kidney development besides forming most of the non-tumor related nephrectomies. Routine urinary system examination should be suggested to patients with a history of urolithiasis in order to prevent later probable organ losses.

Keywords

• Urolithiasis, non-functioning kidney, nephrectomy

Nonfonksiyone böbrekte nefrektominin en sık sebebi: Ürolitiyazis

Abstract

Amaç: Kliniğimizde nefrektomi yapılan hastaları değerlendirerek, ürolitiyazise sekonder non-fonksiyone böbreğe bağlı nefrektomi yapılan hastaların karakteristiklerini sunmayı amaçladık. Yöntemler: Ocak 2000- Aralık 2012 tarihleri arasında kliniğimizde nefrektomi yapılan toplam 696 hasta retrospektif olarak incelendi. Tümör dışı, üriner sistem taşına bağlı non-fonksiyone böbrek nedeniyle nefrektomi yapılan hastaların etiyolojileri ve klinik karakteristikleri değerlendirildi. Hastaların tanılarını doğrulamada üriner sistem ultrasonografi, batın bilgisayarlı tomografi, intravenöz ürografi ve renal sintigrafi tetkikleri kullanıldı. Bulgular: Toplam 696 hastanın 280\'i (%40,2) tümör nedeniyle, 416\'sı (%59,8) ise non-fonksiyone böbrek nedeniyle nefrektomi yapıldı. Non-fonksiyone böbrek vakalarının %43,8 (182) ini üst üriner trakt taşları oluşturmaktaydı. Ürolitiyazise bağlı nefrektomi yapılan hastaların yaş ortalaması 43,7±16,9 idi. Hastaların 97\'si (%53,3) erkek, 85\'i (%46,7) bayan idi. Hastaların preoperatif ortalama kreatin değeri 0,98±0,47 mg/dl olarak tespit edildi. Taşlar 148 (%81,3) hastada renal pelviste üreteropelvik bileşkede, 26 (%14,3) hastada üreterde, 8 (%4,4) hastada ise renal+üreter yerleşimli idi. Renal pelviste üreteropelvik bileşkedeki taşların %66,8\'ini 10-30 mm arası taşlar oluşturmakta idi. Sonuçlar: Üst üriner trakt taşları tümör dışı nefrektomilerin büyük bölümünü oluşturmakla birlikte, non-fonksiyone böbrek gelişiminde primer ana faktördür. İleride oluşabilecek muhtemel organ kayıplarını önlemek için ürolitiyazis öyküsü olan hastaların düzenli üriner sistem muayenesi yaptırmaları önerilmelidir.

Keywords

• Ürolitiyazis, non-fonksiyone böbrek, nefrektomi

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