The relationship between idiopathic chest pain, Vitamin D deficiency and insufficiency in school children and adolescents

Abstract

Objective: The aim of this study is to determine an association between vitamin D status and idiopathic chest pain in school children and adolescents. Methods: Included in the study were a control group of 60 healthy children for comparison with 120 school children and adolescents referred to our pediatric cardiology department, after being diagnosed with idiopathic chest pain. A patient\'s examination included taking a history and doing a physical examination, chest radiograph, electrocardiogram, echocardiogram complete blood count, and 25-hydroxyvitamin D and troponin I levels. Results: Age, gender distribution, and body mass index were not statistically different between the control and study groups (p=0.7, p=0.2 and p=0.3, respectively). Histories of the patients with idiopathic chest pain revealed 22% with heart disease and 6% with recent death in the family. Chest pain was present for 1 month in 19.2%, and for

Keywords

• Idiopathic chest pain, vitamin D deficiency, child

The relationship between idiopathic chest pain, Vitamin D deficiency and insufficiency in school children and adolescents

Abstract

Amaç: Okul çocuğu ve ergenlerde, nedeni bilinmeyen göğüs ağrısı ile vitamin D düzeyinin ilişkisini belirlemek amaçlanmıştır. Yöntemler: Çalışmamıza, nedeni bilinmeyen göğüs ağrısı şikayeti ile pediatrik kardiyoloji birimimize başvuran 120 okul çocuğu ve ergen ile genel polikliniğimize başvuran 60 sağlıklı kontrol hastası alındı. Öykü alınması ve fizik muayenenin ardından, biyokimyasal testler (tam kan sayımı, kan biyokimyası, troponin I ve vitamin D düzeyi) akciğer grafisi, elektrokardiyogram, ekokardiyogram tüm hastalarda değerlendirildi. Bulgular: Çalışma grubu ile kontrol grubu arasında yaş, cinsiyet dağılımı ve vücut kitle indeksi açısından anlamlı fark saptanmadı (sırasıyla, p=0,7, 0,2 ve 0,3). Çalışma grubunda %22 hastanın aile öyküsünde kalp hastalığı, %6 &lsquo;sında ani ölüm olduğu saptandı. Çalışma grubunda, göğüs ağrısının %19,2 hastada 1 aydır, %79,2 hastada 1 aydan uzun sürdüğü; %64\'ünde sol prekordiyumda, %32\'sinde sağ prekordiyumda, %18\'inde midsternal alanda olduğu öğrenildi. Göğüs ağrısı sıklığı ve süresi değişkendi. Serum vitamin D düzeyi çalışma grubunda kontrol hastalarına göre anlamlı derecede düşüktü (p< 0,0001). Alkalen fosfataz dışında biyokimyasal parametrelerde iki grup arasında fark saptanmadı. Göğüs ağrısı süresi ve ağrı sıklığı serum vitamin D düzeyi düşüklüğü ile ilşikili bulundu (r= 0,621, p=0,002 ve r=0,213, p=0,02). Sonuç: Çocukluk çağında sebebi bilinmeyen göğüs ağrısının süresi ve sıklığı ile serum vitamin D eksiliği ve yetersizliği arasında ilişki saptanmıştır.

Keywords

• nedeni belli olmayan göğüs ağrısı, vitamin D eksikliği, çocuk

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