The effects of carotid artery stenting on short-term clinical outcomes and evaluation of restenosis

Year 2011, , 398 - 404, 01.12.2011

Oktay Ergene Cem Nazlı Fatih Toptancı Hamza Duygu Uğur Kocabaş Nihan Kahya Eren Zehra İlke Akyıldız Rida Berilğen Sefa Nuri Akdemir

https://doi.org/10.5798/diclemedj.0921.2011.04.0057

Abstract

Objectives: Data on restenosis and long-term outcomes of carotid stenting are limited. The aim of this study was to investigate cardiovascular effects of carotid stenting on clinical outcome and restenosis in patients with symptom­atic severe carotid artery stenosis. Materials and methods: Twenty patients (mean age: 68±7 years, 11 male) who have been decided to perform stenting in joint Committee of Cardiology, Cardiovascu­lar Surgery and Neurology Clinics were included.Patients were evaluated both clinically and Doppler ultrasono­graphically for frequency of cardiovascular events and restenosis. Restenosis is defined as the reapperance of stenosis with a diameter reduction of ≥%50 with peak sys­tolic velocity higher than 224 cm/s. Results: Comorbidities in patients were; coronary artery disease in 14, peripheral artery disease in three, and both chronic renal failure and congestive heart failure in two. Stent diameters were ranged from 6 to 8 mm, and stent lengths were 30 and 40 mm. During the procedure 5 pa­tients had predilatation and 19 had postdilatation. None of the patients had >%30 resudial stenosis after the proce­dure. All procedures were technically successful. After the procedure only one transient ischemic attack was seen. There were no restenosis, myocardial infarction, death or stroke at 30th day end of the first year of follow up. Diabetes and heart failure were found as predictors for restenosis. Conclusion: In highly selected cases, carotid artery stenting is an effective and safe method in the short term. Restenosis did not seem to be a restricting problem for the success of carotid artery stenting.

Keywords

Carotid artery stenosis, stenting, restenosis, clinical outcomes

Karotis arter stentlemenin kısa dönem klinik sonuçlara etkisi ve restenozun değerlendirilmesi

Abstract

Amaç: Karotis stentlemede restenoz ve uzun dönem so­nuçlarla ilgili veriler sınırlıdır. Bu çalışmanın amacı semp­tomatik ağır karotis arter darlıklı hastalarda stentleme işleminin klinik sonuçlara ve restenoz oranlarına etkisini araştırmaktır. Gereç ve yöntem: Çalışmaya Kalp Damar Cerrahisi, Kardiyoloji ve Nöroloji ortak konseyinde stent implantas­yonu kararı alınan 20 hasta (yaş ortalaması 68±7 yıl, 11\'i erkek) alındı. Hastalar perioperatif (ilk 30 gün ) ve birinci yıl sonunda hem klinik hem de Doppler ultrasonografi ile değerlendirilerek kardiyovasküler olay sıklığı ve restenoz oranları değerlendirildi. İzlemde karotis Doppler ultraso­nografi ile %50 ve üzeri darlığa karşılık gelen instent zirve akım hızının ≥224 cm/sn olması restenoz olarak kabul edildi. Bulgular: Hastalarda ek hastalık olarak 14\'ünde koroner arter hastalığı, 3\'ünde periferik arter hastalığı, 2\'sinde kro­nik böbrek yetmezliği, 2\'sinde ise kalp yetersizliği mevcut­tu. İşlemde kullanılan stentlerin çapı 6 ile 8 mm arasında, stent uzunluğu ise 30 ile 40 mm idi. Beş (%25) hastaya predilatasyon yapılırken, postdilatasyon 19(%95) hastaya uygulandı. Postdilatasyon sonrası hiçbir hastada ≥%30 rezidüel darlık izlenmedi. İşlem başarısı %100\'dü. İşlem sonrası periprosedürel olay kapsamında 1(%5) hastada geçici iskemik atak gelişti. Otuz günlük ve bir yıllık takip­lerde inme, miyokard infarktüsü veya ölüm görülmedi. Hiçbir hastada restenoz izlenmedi. Diyabet ve kalp yeter­sizliği restenoz öngördürücü faktörleri olarak saptandı. Sonuç: Karotis arter stentleme iyi seçilmiş olgularda kısa dönemde etkin ve güvenilir bir yöntemdir. Restenoz karo­tis arter darlığında işlem başarısını etkileyen kısıtlayıcı bir faktör olarak görünmemektedir.

Keywords

Karotis arter darlığı, stent, restenoz, klinik sonuçlar

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