Examination of liver metastases with contrast enhanced ultrasonography

Abstract

Objectives: To investigate the effect of contrast enhanced ultrasonography in examination of liver metastases Materials and methods: Totally 13 metastatic liver lesions were examined in 13 cases. These lesions were exam-ined by dynamic contrast enhanced ultrasonography with Levovist 2.5/4 gr. flk (contrast agent that contains galactose and palmitic acid). Vascular phase (arterial-portal) and parenchymal phase enhancement patterns were investigated in these lesions. Results: The sensitivity and specifity of vascular phase enhancement and later phase perfusion defect in these le-sions were found as %76.92 and %100 respectively. Conclusion: Dynamic contrast enhanced ultrasonography is an effective method in characterization of liver metasta-ses.

Keywords

• Doppler, liver, liver metastases, liver ultrasonography, contrast media.

Examination of liver metastases with contrast enhanced ultrasonography

Abstract

Amaç: Karaciğer metastazlarının incelenmesinde, kontrastlı ultrasonografinin etkinliğinin araştırılması. Gereç ve yöntem: Toplam 13 olguda 13 adet metastatik karaciğer lezyonu incelendi. Bu lezyonlar, Levovist 2,5/4 gr. flk (galaktoz ve palmitik asit içeren ekokontrast ajan) kullanılarak dinamik kontrastlı US ile incelendi. Lezyonlarda vasküler (arteryel-portal) ve parankimal fazda kontrastlanma paternleri araştırıldı. Bulgular: Lezyonların vasküler fazda kontrast tutup, geç fazda perfüzyon defekti izlenmesinin sensitivite ve spesifisi-tesi sırayla %76,9 ve %100 olarak bulundu. Sonuç: Karaciğer metastazlarının incelenmesinde, dinamik kontrastlı ultrasonografi etkin bir yöntemdir.

Keywords

• Doppler, karaciğer, karaciğer metastazları, karaciğer ultrasonografisi, kontrast madde.

References

1. İnal M, Demirci A. Karaciğer kitlelerinin kontrastlı dinamik akım ultrasonografi ile incelenmesi. Cer San D (J Surg Arts) 2011;4(1):1-10.
2. Harvey CJ, Blomley MJK, Eckersley RJ, Cosgrove DO. Developments in ultrasound contrast media. Eur Radiol 2001;11(4):675-89.
3. Tanaka S, Ioka T, Oshikawa O, Hamada Y, Yoshioka F. Dy- namic sonography of hepatic tumors. AJR Am J Reontgen- ol 2001;177(4):799-805.
4. Koiko K, Hirokawa T, Ichimura T, Hareyama M. Dynamic flow enhances abdominal imaging. Advanced Ultrasound 2001;(19):17-20.
5. Solbiati L, Tonolini M, Cova L, Goldberg SN. The role of contrast enhanced ultrasound in the detection of focal liver lesions. Eur Radiol 2001;11(3):15-26
6. Leen E. The role of contrast enhanced ultrasound in the char- acterisation of focal liver lesions. Eur Radiol 2001;11(3):27- 34
7. Harvey CJ, Albrecht T. Ultrasound of focal liver lesions. Eur Radiol 2001;11(9):1578-93.
8. Sandulescu L, Saftoiu A, Dumitrescu D, Ciurea T. The Role of Real-time contrast-enhanced and real-time virtual so- nography in the assessment of malignant liver lesions. J Gastrointestin Liver Dis 2009:18(1):103-8.

9. İnal M. Dinamik kontrastlı ultrasonografi ile incelenen hepa- tosellüler karsinoma olgusu. Van Tıp Dergisi, 2012; baskıda
10. Chami L, Lassa N, Malka D, et al. Benefits of contrast- enhanced sonography for the detection of liver lesions: comparison with histologic findings. AJR Am J Reontgenol 2008;(190):683-90.