Comparison of the depth of anesthesia in sevoflurane and halothane anesthesia with bispectral index and 95% spectral edge frequency

Abstract

Objective: The aim of the present study was to evaluate the depth of anesthesia provided by halothane or sevoflurane by using the bispectral index (BIS) and 95% spectral edge frequency (SEF) monitoring systems. Methods: Forty patients, between the ages of 20-60 years, scheduled for gynecological surgery under general anesthesia were studied between the years 2001-2002. Anesthesia induction was maintained by conventional spontaneous inhalation induction method with sevoflurane in the group I patients (n=20), with halothane in the group II patients (n=20). SEF and BİS index values were recorded. Results: In both groups, SEF values recorded before intubation, after intubation, before and after skin incision were significantly lower compared with values recorded at baseline (p

Keywords

• Bispectral index, halothane, sevoflurane, anesthesia depth, hemodynamic responses

Bispektral indeks ve %95 spektral edge frekans ile halotan ve sevofluran anestezi derinliklerinin karşılaştırılması

Abstract

Amaç: Bu çalışmanın amacı, bispektral indeks (BİS) ve % 95 spektral edge frekans (SEF) monitorizasyon sistemleri kullanarak, halotan ve sevofluran anestezi derinliklerinin değerlendirilmesidir. Yöntemler: 2001-2002 yılları arasında, yaşları 20 ile 60 arasında değişen, genel anestezi altında jinekolojik operasyon geçiren 40 hasta çalışmaya dahil edildi. Anestezi indüksiyonu Grup I hastalarda (n=20) halotan, Grup II hastalarda sevofluran ile konvansiyonel spontan inhalasyon indüksiyon metodu ile sağlandı. SEF ve BIS indeks değerleri kaydedildi. Bulgular: Her iki grupta entübasyon öncesi ve sonrası, cilt insizyon öncesi ve sonrası SEF değerleri, bazal değerlerine göre anlamlı derecede düşüktü (p

Keywords

• Bispectral indeks, halotan, sevofluran, anestezi derinliği, hemodinamik değişiklikler

References

1. Rosow C, Manberg PJ. Bispectral index monitoring. Anesth Clin N Am 1998;2:89-107.
2. Stanski DR. Monitoring depth of anesthesia. In: Miller RD (ed), Anesthesia. Churchill Livingstone Inc, New York 2000, pp 1087-1116.
3. Pino RM, Ali HH, Denman WT, et al. A comparison of the intubation conditions between mivacurium and rocuronium during balanced anesthesia. Anesthesiology 1998;88:673- 678.
4. Ruffle JM, Snider MT, Rosenberger JL, et al. Rapid in- duction of halothane anaesthesia in man. Br J Anaesth 1985;57:607-611.
5. Muzi M, Robinson BJ, Ebert TJ, et al. Induction of anesthe- sia and tracheal intubation with sevoflurane in adults. Anes- thesiology 1996;85:536-543.
6. Jellish WS, Lien CA, Fontenot HJ, et al. The comparative effects of sevoflurane versus propofol in the induction and maintenance of anesthesia in adult patients. Anesth Analg 1996;82:479-485.
7. Ruffle JM, Snider MT. Comparison of rapid and convention- al inhalation inductions of halothane oxygen anesthesia in healthy men and women. Anesthesiology 1987;67:584-587.
8. Drummond GB. Rapid inhalation induction of anaesthesia. Br J Anaesth 1988;61:373-375.

9. Smith I, Nathanson M, White PF. Sevoflurane a long awaited volatile anaesthetic. Br J Anaesth 1996;76:435-445.
10. Oğuz S, Özalp G, Özmert G, et al. Sevofluran ile anes- tezi indüksiyonunda klasik spontan inhalasyon indüksi- yon yöntemi ile tek vital kapasite soluması yöntemlerinin karşılaştırılması. Türk Anesteziyoloji ve Reanimasyon Ce- miyeti Mecmuası 1998;26:130-133.
11. Stern R, Towler S, White P, et al. Elimination kinetics of sevoflurane and halothane from blood, brain and adipose tissue in the rat. Anesth Analg 1990;7:237-244.
12. Yasuda N, Lockhart SH, Eger II EI, et al. Comparison of kinetics of sevoflurane and isoflurane in humans. Anesth Analg 1991;72:316-324.
13. Yurino M, Kimura H. Vital capacity breathing respiration technique for rapid anaesthetic induction comparison of sevoflurane and isoflurane. Anaesthesia 1992;47:946-949.
14. Immamura S, Ikeda K. Comparison of the epinephrine in- duced arrhytmogenic effect of sevoflurane and halothane. J Anaesth 1987;1:62-68.
15. Tanaka S, Tsuchida H, Nakabayashi K-I, et al. The effects of sevoflurane, isoflurane, halothane and enflurane on hae- modynamic responses during an inhaled induction of anes- thesia a mask in humans. Anesth Analg 1996;82:821-826.
16. Hall J, Ebert TJ, Harmer M. Induction characteristics with 3% and 8% sevoflurane in adults: An evaluation of the second stage of anaesthesia and its haemodynamic conse- quences. Anaesthesia 2000;55:545-550.
17. Glass PS, Bloom M, Kearse L, et al. Bispectral analysis measures sedation and memory effects of propofol, mid- azolam, isoflurane and alfentanil in healthy volunteers. An- esthesiology 1997;86:836-847.
18. Flaishon R, Windsor A, Sigl J, et al. Recovery of conscious- ness after thiopental or propofol: BIS and the isolated fore- arm technique. Anesthesiology 1997;86:613-619.
19. Schwender D, Daunderer M, Mulzar S, et al. Spectral edge frequency of the electroencephalogram to monitor “depth” of anaesthesia. Br J Anaesth 1996;77:179-184.
20. Sawtelle K, Rampil I. Bispectral EEG index predicts awak- ening. Anesthesiology 1994;81:A213.