Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients

Yavuz Pirhan

doi:10.5798/dicletip.705908

Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients

Abstract

Objective: In stage III gastric cancer patients who underwent resection, prognostic factors related to patient, tumor and treatment and their survival effects were investigated. Method: One-hundred sixty three patients were included in the study and data was obtained retrospectively from hospital records. Investigated parameters; patient-related factors (age,gender,bloodgroup,preoperativehemoglobin,albumin and serum tumor marker (carcinoembryonic antigen(CEA), cancer antigen 19-9(CA 19-9) levels), tumor related factors (tumor localization, tumor size , T and N stage, total lymph node count, metastatic/total lymph node ratio, surgical margin of tumor, pathology, differentiation, lymphovascular and perineural invasion status) and treatment-related factors (adjuvant treatment, nutritional support, and blood transfusion). Results: Fifty-one out of the 163 patients were female, and the median age was 60. In univariate analysis, serum Ca19-9 level(p=0,03), serum CEA level(p=0.01) and the lymph node ratio(p=0.002) were found to be an independent factors associated with overall survival whereas only lymph node ratio was an effective parameter in multivariate analysis[(p = 0.004, relative risk =0.50, 95% confidence interval (0.32-0.80)]. When the study was finalized, patients were followed for a median of 16 months, 87 patients(53.4%) died due to the disease. Conclusion: The metastatic tumor load in the lymph nodes around the stomach was negatively effective on survival. This result demonstrates the importance of lymphatic dissection.

Keywords

Gastriccancer,prognosticfactors

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Yavuz Pirhan ^* This is me
Türkiye

Publication Date

March 17, 2020

Submission Date

October 10, 2019

Acceptance Date

January 7, 2020

Published in Issue

Year 2020 Volume: 47 Number: 1

DOI

https://doi.org/10.5798/dicletip.705908

IZ

https://izlik.org/JA68DG76WA

Cite

RIS / Bibtex

APA

Pirhan, Y. (2020). Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients. Dicle Medical Journal, 47(1), 34-42. https://doi.org/10.5798/dicletip.705908

AMA

1.Pirhan Y. Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients. Dicle Medical Journal. 2020;47(1):34-42. doi:10.5798/dicletip.705908

Chicago

Pirhan, Yavuz. 2020. “Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients”. Dicle Medical Journal 47 (1): 34-42. https://doi.org/10.5798/dicletip.705908.

EndNote

Pirhan Y (March 1, 2020) Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients. Dicle Medical Journal 47 1 34–42.

IEEE

[1]Y. Pirhan, “Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients”, Dicle Medical Journal, vol. 47, no. 1, pp. 34–42, Mar. 2020, doi: 10.5798/dicletip.705908.

ISNAD

Pirhan, Yavuz. “Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients”. Dicle Medical Journal 47/1 (March 1, 2020): 34-42. https://doi.org/10.5798/dicletip.705908.

JAMA

1.Pirhan Y. Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients. Dicle Medical Journal. 2020;47:34–42.

MLA

Pirhan, Yavuz. “Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients”. Dicle Medical Journal, vol. 47, no. 1, Mar. 2020, pp. 34-42, doi:10.5798/dicletip.705908.

Vancouver

1.Yavuz Pirhan. Analysis of Prognostic Factors Affecting Postoperative Survival in Stage III Gastric Cancer Patients. Dicle Medical Journal. 2020 Mar. 1;47(1):34-42. doi:10.5798/dicletip.705908