Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients

Alper Sarı; Memnune Sena Ulu; Sinan Kazan; Onur Tunca; Elif Dizen Kazan

doi:10.5798/dicletip.706097

Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients

Abstract

Objective: Chronic kidney disease (CKD) is an inflammatory process. Serum proinflammatory cytokines are known to be ten times higher in patients with CKD when compared to normal population. Monocyte/High density lipoprotein (HDL) cholesterol ratio (MHR) have been shown to be a new marker of inflammation and claimed that, it may be used to predict cardiovascular events in patients with CKD. This cross-sectional study aimed to compare monocyte / HDL cholesterol ratio in patients treated with hemodialysis and peritoneal dialysis. Methods: Files of patients who have been followed up with end stage renal disease (ESRD) and have peritoneal dialysis or hemodialysis therapy in Nephrology Clinic of our hospital have been retrospectively examined. Patients were divided into two groups regarding renal replacement treatment type. Monocyte / HDL cholesterol ratio was compared between groups. IBM SPSS Statistics 22.0 (IBM Corp., NY, USA) packaged software and appropriate statistical methods were used to analyse data. Results: Monocyte / HDL cholesterol ratio was significantly higher in patients treated with hemodialysis (p= 0.028). HDL cholesterol levels were significantly higher in peritoneal dialysis group (p= 0.046). Total cholesterol, LDL cholesterol, triglyceride and VLDL cholesterol have been ascertained to be similar in both patient groups (p> 0.05). The high sensitivity CRP and sedimentation levels have been detected to be similar within the groups (p> 0.05). Conclusion: This is the first study evaluating the monocyte/HDL cholesterol ratio among renal replacement therapy modalities in our literature review. In this study, it has been shown that; monocyte/HDL cholesterol ratio were statistically higher in patients having hemodialysis than in the ones followed up with peritoneal dialysis. According to these results, it may be considered that; peritoneal dialysis may be associated with less systemic inflammation than hemodialysis.

Keywords

dialysis,inflammation,monocyte

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Alper Sarı This is me
Türkiye

Memnune Sena Ulu This is me
Türkiye

Sinan Kazan This is me
Türkiye

Onur Tunca This is me
Türkiye

Elif Dizen Kazan This is me
Türkiye

Publication Date

March 17, 2020

Submission Date

February 4, 2020

Acceptance Date

March 5, 2020

Published in Issue

Year 2020 Volume: 47 Number: 1

DOI

https://doi.org/10.5798/dicletip.706097

IZ

https://izlik.org/JA28NM83UC

Cite

RIS / Bibtex

APA

Sarı, A., Ulu, M. S., Kazan, S., Tunca, O., & Kazan, E. D. (2020). Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. Dicle Medical Journal, 47(1), 139-137. https://doi.org/10.5798/dicletip.706097

AMA

1.Sarı A, Ulu MS, Kazan S, Tunca O, Kazan ED. Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. Dicle Medical Journal. 2020;47(1):139-137. doi:10.5798/dicletip.706097

Chicago

Sarı, Alper, Memnune Sena Ulu, Sinan Kazan, Onur Tunca, and Elif Dizen Kazan. 2020. “Comparison Of Monocyte HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients”. Dicle Medical Journal 47 (1): 139-37. https://doi.org/10.5798/dicletip.706097.

EndNote

Sarı A, Ulu MS, Kazan S, Tunca O, Kazan ED (March 1, 2020) Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. Dicle Medical Journal 47 1 139–137.

IEEE

[1]A. Sarı, M. S. Ulu, S. Kazan, O. Tunca, and E. D. Kazan, “Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients”, Dicle Medical Journal, vol. 47, no. 1, pp. 139–137, Mar. 2020, doi: 10.5798/dicletip.706097.

ISNAD

Sarı, Alper - Ulu, Memnune Sena - Kazan, Sinan - Tunca, Onur - Kazan, Elif Dizen. “Comparison Of Monocyte HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients”. Dicle Medical Journal 47/1 (March 1, 2020): 139-137. https://doi.org/10.5798/dicletip.706097.

JAMA

1.Sarı A, Ulu MS, Kazan S, Tunca O, Kazan ED. Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. Dicle Medical Journal. 2020;47:139–137.

MLA

Sarı, Alper, et al. “Comparison Of Monocyte HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients”. Dicle Medical Journal, vol. 47, no. 1, Mar. 2020, pp. 139-7, doi:10.5798/dicletip.706097.

Vancouver

1.Alper Sarı, Memnune Sena Ulu, Sinan Kazan, Onur Tunca, Elif Dizen Kazan. Comparison Of Monocyte / HDL Ratio In Routine Hemodialysis And Peritoneal Dialysis Patients. Dicle Medical Journal. 2020 Mar. 1;47(1):139-7. doi:10.5798/dicletip.706097

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Cureus

https://doi.org/10.7759/cureus.20345