Cerebral Hemodynamic Response To Menstrual Cycle In Migraine

Ayca Ozkul; Hasibe Ozgecen Dincel; Ali Akyol

doi:10.5798/dicletip.799867

TR EN

Cerebral Hemodynamic Response To Menstrual Cycle In Migraine

Abstract

Objective: Menstrually related migraine (MRM) occurs in relation to menstrual cycles. We investigated the cerebral hemodynamic response to the menstrual cycle in nonmenstrually related migraines (nMRM), MRM and healthy controls. Methods: 22 nMRM, 20 MRM patients in an attack-free interval and 20 healthy volunteers were included in our study. TCD recordings were made during the follicular and luteal phases of the hormonal cycle and mean flow velocity values of middle and posterior cerebral arteries were studied. Cerebral vasomotor reactivity (CVR) was evaluated by breath holding index (BHI) and visually evoked blood flow (VEBF) changes in both phases of the same menstrual cycle. Results: Mean flow veloticities and hormone levels were not different between groups. Right BHI and bilateral VEBF values were significantly lower in both of the migraine groups. The physiological elevation of CVR in the luteal phase was detected in the control and nMRM groups, but not in the MRM group. Conclusion: The cerebral hemaodynamics were affected in both MRM and nMRM. Additionally the physiological CVR to menstrual cycle was impaired in MRM. The impairment in cerebral hemodynamic response to the menstrual cycle in MRM needs further research to discover the underlying pathophysiology.

Keywords

References

1.Klein E., Spencer D. Migraine frequency and risk ofcardiovascular disease in women. Neurology. 2009;73: 42–3.
2.Headache Classification Committee of theInternational Headache Society (IHS). TheInternational Classification of Headache Disorders,3rd edition (beta version). Cephalalgia. 2013; 33:629-808.
3.Brandes JL. Migraine in women. Continuum(Minneap Minn) 2012 Aug; 18: 835-52.
4.Allais G, Benedetto C. Update on menstrualmigraine: from clinical aspects to therapeuticalstrategies Neurol Sci. 2004; 25: 229–31

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Ayca Ozkul ^* This is me
Türkiye

Hasibe Ozgecen Dincel This is me
Türkiye

Ali Akyol This is me
Türkiye

Publication Date

September 25, 2020

Submission Date

July 11, 2020

Acceptance Date

September 16, 2020

Published in Issue

Year 2020 Volume: 47 Number: 3

DOI

https://doi.org/10.5798/dicletip.799867

IZ

https://izlik.org/JA96EP94TA

Cite

RIS / Bibtex

APA

Ozkul, A., Dincel, H. O., & Akyol, A. (2020). Cerebral Hemodynamic Response To Menstrual Cycle In Migraine. Dicle Medical Journal, 47(3), 578-586. https://doi.org/10.5798/dicletip.799867

AMA

1.Ozkul A, Dincel HO, Akyol A. Cerebral Hemodynamic Response To Menstrual Cycle In Migraine. Dicle Medical Journal. 2020;47(3):578-586. doi:10.5798/dicletip.799867

Chicago

Ozkul, Ayca, Hasibe Ozgecen Dincel, and Ali Akyol. 2020. “Cerebral Hemodynamic Response To Menstrual Cycle In Migraine”. Dicle Medical Journal 47 (3): 578-86. https://doi.org/10.5798/dicletip.799867.

EndNote

Ozkul A, Dincel HO, Akyol A (September 1, 2020) Cerebral Hemodynamic Response To Menstrual Cycle In Migraine. Dicle Medical Journal 47 3 578–586.

IEEE

[1]A. Ozkul, H. O. Dincel, and A. Akyol, “Cerebral Hemodynamic Response To Menstrual Cycle In Migraine”, Dicle Medical Journal, vol. 47, no. 3, pp. 578–586, Sept. 2020, doi: 10.5798/dicletip.799867.

ISNAD

Ozkul, Ayca - Dincel, Hasibe Ozgecen - Akyol, Ali. “Cerebral Hemodynamic Response To Menstrual Cycle In Migraine”. Dicle Medical Journal 47/3 (September 1, 2020): 578-586. https://doi.org/10.5798/dicletip.799867.

JAMA

1.Ozkul A, Dincel HO, Akyol A. Cerebral Hemodynamic Response To Menstrual Cycle In Migraine. Dicle Medical Journal. 2020;47:578–586.

MLA

Ozkul, Ayca, et al. “Cerebral Hemodynamic Response To Menstrual Cycle In Migraine”. Dicle Medical Journal, vol. 47, no. 3, Sept. 2020, pp. 578-86, doi:10.5798/dicletip.799867.

Vancouver

1.Ayca Ozkul, Hasibe Ozgecen Dincel, Ali Akyol. Cerebral Hemodynamic Response To Menstrual Cycle In Migraine. Dicle Medical Journal. 2020 Sep. 1;47(3):578-86. doi:10.5798/dicletip.799867