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The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure

Year 2020, , 812 - 819, 30.12.2020
https://doi.org/10.5798/dicletip.850294

Abstract

References

  • 1.Yancy CW, Jessup M, Bozkurt B, et al. 2013ACCF/AHA guideline for the management of heartfailure: a report of the American College of Cardiology Foundation/American Heart Association Task Forceon Practice Guidelines. J. Am. Coll. Cardiol. 2013; 62:e147-e239.

The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure

Year 2020, , 812 - 819, 30.12.2020
https://doi.org/10.5798/dicletip.850294

Abstract

Objective: We purposed to evaluate the association between Monocyte To High-Density Lipoprotein Cholesterol Ratio (MHR) and mortality during a year follow-up in patients with reduced efection fraction heart failure (HFrEF).
Method: We included total of 552 patients with HFrEF into the study. The main outcome was mortality at 1-year follow-up. Sociodemographic characteristics, hemogram and biochemical parameters, ejection fractions of patients were recorded. MHR was was computed by splitting monocyte into high-density lipoprotein cholesterol (HDL-C).
Results: The HFrEF population were seperated into different groups as non-survivors (n=45) and survivors (n=507). When the groups are compared the non-survivors group was older (p=0.04) and chronic renal failure incidence was higher in non-survivors (p=0.001). The MHR was notably higher in the non-survivors group (p=0.000). We have shown that MHR had a positive correlation with mortality (r=0.146 p=0.001). Also higher MHR was found as a strong paramer to predict of mortality (Odds ratio: 2.471, 95% confidence interval: 1.729–4.092, P=0.005). The cut-off values of 6,39 might be applied for predicting the mortality with 88% sensitivity and 97% specificity [Area under curve:0.831 (95% Confidence Interval: 0.799-0.869) p=0.001].
Conclusion: MHR can be used as an easy and usefull tool to predict mortality in HFrEF patients.

References

  • 1.Yancy CW, Jessup M, Bozkurt B, et al. 2013ACCF/AHA guideline for the management of heartfailure: a report of the American College of Cardiology Foundation/American Heart Association Task Forceon Practice Guidelines. J. Am. Coll. Cardiol. 2013; 62:e147-e239.
There are 1 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Articles
Authors

Seçkin Dereli This is me

Publication Date December 30, 2020
Submission Date November 24, 2020
Published in Issue Year 2020

Cite

APA Dereli, S. (2020). The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure. Dicle Tıp Dergisi, 47(4), 812-819. https://doi.org/10.5798/dicletip.850294
AMA Dereli S. The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure. diclemedj. December 2020;47(4):812-819. doi:10.5798/dicletip.850294
Chicago Dereli, Seçkin. “The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure”. Dicle Tıp Dergisi 47, no. 4 (December 2020): 812-19. https://doi.org/10.5798/dicletip.850294.
EndNote Dereli S (December 1, 2020) The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure. Dicle Tıp Dergisi 47 4 812–819.
IEEE S. Dereli, “The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure”, diclemedj, vol. 47, no. 4, pp. 812–819, 2020, doi: 10.5798/dicletip.850294.
ISNAD Dereli, Seçkin. “The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure”. Dicle Tıp Dergisi 47/4 (December 2020), 812-819. https://doi.org/10.5798/dicletip.850294.
JAMA Dereli S. The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure. diclemedj. 2020;47:812–819.
MLA Dereli, Seçkin. “The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure”. Dicle Tıp Dergisi, vol. 47, no. 4, 2020, pp. 812-9, doi:10.5798/dicletip.850294.
Vancouver Dereli S. The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure. diclemedj. 2020;47(4):812-9.