Evaluation of Corneal Optic Quality in Amblyopia
Abstract
Objective: To compare corneal aberrations and densitometry values in children with amblyopia due to anisometropic hyperopia with those of healthy children.
Methods: This study included 173 children with amblyopia due to hyperopic anisometropia in one eye and 173 children with both healthy eyes. The amblyopic eye (Group 1) and the fellow normal eye (Group 2) of the amblyopic patients and the right eye of the healthy control group (Group 3) were evaluated. Of the corneal aberration and corneal densitometry (CD)measured using Scheimpflug corneal topography values were noted.
Results: While there was a significant difference in total root mean square (RMS), higher-order aberration (HOA) RMS, coma horizontal, trefoil horizontal and spherical aberration values between the groups (p<0.001, p<0.001, p<0.001, p<0.001, p=0.008, respectively), there was no difference between coma vertical and trefoil oblique values (p=0.076, p=0.074, respectively). There was no significant difference in terms of CD values in the anterior 0–2mm and 2–6mm regions between the groups (p=0.081, p=0.054,respectively). However, the difference between the groups in the central (0-2mm, 2-6mm) and posterior (0-2mm, 2-6mm) area was statistically significant (p<0.001, p=0.009, p=0.009, p<0.001, respectively). In addition, the difference between the groups in the total 0-2mm and 2-6mm area was statistically significant (p=0.001, p<0.001, respectively).
Conclusions: Total HOA values were higher in amblyopic eyes compared to the fellow normal eye. Central and posterior corneal densitometry values were decreased in patients’ amblyopic eyes compared to their fellow eye. This may be related to some compensation mechanisms and/or microstructural changes in the cornea.
Keywords
Evaluation of Corneal Optic Quality in Amblyopia
Abstract
Objective: To compare corneal aberrations and densitometry values in children with amblyopia due to anisometropic hyperopia with those of healthy children.
Methods: This study included 173 children with amblyopia due to hyperopic anisometropia in one eye and 173 children with both healthy eyes. The amblyopic eye (Group 1) and the fellow normal eye (Group 2) of the amblyopic patients and the right eye of the healthy control group (Group 3) were evaluated. Of the corneal aberration and corneal densitometry (CD)measured using Scheimpflug corneal topography values were noted.
Results: While there was a significant difference in total root mean square (RMS), higher-order aberration (HOA) RMS, coma horizontal, trefoil horizontal and spherical aberration values between the groups (p<0.001, p<0.001, p<0.001, p<0.001, p=0.008, respectively), there was no difference between coma vertical and trefoil oblique values (p=0.076, p=0.074, respectively). There was no significant difference in terms of CD values in the anterior 0–2mm and 2–6mm regions between the groups (p=0.081, p=0.054,respectively). However, the difference between the groups in the central (0-2mm, 2-6mm) and posterior (0-2mm, 2-6mm) area was statistically significant (p<0.001, p=0.009, p=0.009, p<0.001, respectively). In addition, the difference between the groups in the total 0-2mm and 2-6mm area was statistically significant (p=0.001, p<0.001, respectively).
Conclusions: Total HOA values were higher in amblyopic eyes compared to the fellow normal eye. Central and posterior corneal densitometry values were decreased in patients’ amblyopic eyes compared to their fellow eye. This may be related to some compensation mechanisms and/or microstructural changes in the cornea
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