Ciprofloxacin is not a better choice in the patients with diabetes suffering urinary tract infection
Abstract
Objective:
The aim of this study is to determine antibacterial susceptibilities of
Gram-negative bacteria isolated from diabetic and non-diabetic patients as
infectious agents of community-acquired urinary tract infections (UTI) and to
compare their rates of resistance to the antibiotics frequently used in
empirical treatment.
Methods:
Ninety-six diabetic and sixty-eight non-diabetic (total n=164) patients’ data
were evaluated retrospectively who diagnosed as community-acquired urinary
system infection and consulted to outpatient clinics of Department of
Endocrinology and Infectious Diseases of Firat University School of Medicine
between January 1st , 2014 and December 31st, 2014 whose urine cultures
demonstrated Gram-negative bacteria were included in the study. Antibiotic
susceptibilities of the isolated bacteria were determined using Vitek 2
automated system and the results were evaluated as sensitive and resistant.
Results: In
both diabetic and non-diabetic patient groups, most frequently Escherichia coli
(88.5% in diabetic and 85.3% in non-diabetic groups) were isolated. In the
diabetic group, microorganisms mostly demonstrated the highest rates of
resistance against ampicillin, cephalosporins, ciprofloxacin,
amoxicillin-clavulanic acid and in the non-diabetic group ampicillin,
amoxicillin-clavulanic acid, cefuroxime and trimethoprim-sulfamethoxazole.
Conclusion:
Resistance to ciprofloxacin was at a significantly higher rate in the diabetic
group. In diabetic patients, it will be more appropriate to give antibiotherapy
in urinary system infections based on the antibacterial susceptibility test
results.
Keywords
References
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Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Research Article |
| Authors | |
| Publication Date | March 3, 2019 |
| Submission Date | October 25, 2018 |
| Published in Issue | Year 2019 Volume: 46 Issue: 1 |