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A rare case of leiomyoma: Retroperitoneal leiomyoma

Year 2014, Volume: 41 Issue: 2, 414 - 417, 01.06.2014
https://doi.org/10.5798/diclemedj.0921.2014.02.0443

Abstract

Primary retroperitoneal leiomyoma is a rare and unusual differential diagnosis in the gynecological practice. The pathogenesis of retroperitoneal leiomyoma remains obscure. A 49-year-old nulligravida woman admitted to our hospital with complaints of nocturia, lower abdominal pain and a large abdominopelvic mass. The diagnostic workup included transabdominal ultrasonography, contrast computerized tomography and magnetic resonance imaging that revealed a 15-cm homogeneous pelvic mass with multiple septations. Retroperitoneal leiomyoma was suspected on imaging studies and was confirmed by tumor excision and histopathological examination.

References

  • Cohen DT, Oliva E, Hahn PF, et al. Uterine smooth-muscle tumors with unusual growth patterns: imaging with patho- logic correlation. AJR Am J Roentgenol 2007;188:246-255.
  • Kilpatrick SE, Mentzel T, Fletcher CDM. Leiomyoma of deep soft tissue: A clinicopathologic series. Am J Surg Pat- hol 1994;18:576-582.
  • Fasih N, Prasad Shanbhogue AK, Macdonald DB, et al. Lei- omyomas beyond the uterus: unusual locations, rare mani- festations. Radiographics 2008;28:1931-1948.
  • Kempson RL, Hendrickson MR. Pure mesenchymal neoplas- ms of the uterine corpus: selected problems. Semin Diagn Pathol 1988;5:172-198.
  • Uchida T, Tokumaru T, Kojima H, et al. A case of multiple leiomyomatous lesions of the lung: an analysis of flow cy- tometry and hormone receptors. Surg Today 1992;22:265- 268.
  • Poliquin V, Victory R, Vilos GA. Epidemiology, presentati- on, and management of retroperitoneal leiomyomata: sys- tematic literature review and case report. J Minim Invasive Gynecol 2008;15:152-160.
  • Paal E, Miettinen M. Retroperitoneal leiomyomas: A clini- copathologic and immunohistochemical study of 56 cases with a comparison to retroperitoneal leiomyosarcomas. Am J Surg Pathol 2001;25:1355-1363.
  • Asal N, Koşar PN, Duymuş M, et al. Pelvic magnetic re- sonance imaging in gynecologic masses. Dicle Med J 2011;38:412-420.
  • Takemura G, Takatsu Y, Kaitani K, et al. Metastasizing uteri- ne leiomyoma. A case with cardiac and pulmonary metasta- sis. Pathol Res Pract 1996;192:622-633.
  • Shukunami K, Nishijima K, Kurokawa T, et al. A benign so- litary uterine leiomyoma on the pelvic peritoneum detected long after the hysterectomy for fibroids. J Obstet Gynaecol 2006;26:589.
  • Funakoshi Y, Sawabata N, Takeda S, Hayakawa M, Okumu- ra Y, Maeda H. Pulmonary benign metastasizing leiomyo- ma from the uterus in a postmenopausal woman: Report of a case. Surg Today 2004; 34:55-57.
  • Okolo SO, Gentry CC, Perrett CW, Maclean AB. Familial prevalence of uterine fibroids is associated with distinct cli- nical and molecular features. Hum Reprod 2005;20:2321- 2324.
  • Nayar AC, McAleer EP, Tunick PA, et al. Benign metas- tasizing leiomyomatosis diagnosed by echocardiography. Echocardiography 2002;19:571-572.
  • Sentinelli S, Covello R, Benevolo M, et al. Benign metas- tasizing pulmonary leiomyoma: description of a case and review of the literature. Pathologica 2002;94:253-256.
  • Goyle KK, Moore DF Jr, Garrett C, Goyle V. Benign metas- tasizing leiomyomatosis: case report and review. Am J Clin Oncol 2003;26:473-476.
  • Fukamachi N, Togami S, Iwamoto I, et al. Retroperitoneal uterine leiomyoma occurring 5 years after hysterectomy for fibroids. J Obstet Gynaecol Res 2007;33:878-881.
  • Zaitoon MM: Retroperitoneal parasitic leiomyoma causing unilateral ureteral obstruction. J Urol 1986;135:130-131.
  • Stutterecker D, Umek W, Tunn R, et al. Leiomyoma of the space of Retzius: a report of 2 cases. Am J Obstet Gynecol 2001;185:248-249.
  • Sinha R, Sundaram M, Mahajan C, Sambhus A. Multiple leiomyoma after laparoscopic hysterectomy: Report of two cases. J Minim Invasive Gynecol 2007;14:123-127.
  • Esteban JM, Allen WM, Schaerf RH. Benign metastasizing leiomyoma of the uterus: histologic and immunohistoche- mical characterization of primary and metastatic lesions. Arch Pathol Lab Med 1999;123:960-962.
  • McLeod AJ, Zornoza J, Shirkhoda A. Leiomyosarcoma: computed tomographic findings. Radiology 1984;152:133- 136.
  • Jacobson TZ, Rainey EJ, Turton CW. Pulmonary benign metastasizing leiomyoma: response to treatment with gose- relin. Thorax 1995;50:1225-1226.
  • Arai T, Yasuda Y, Takaya T, Shibayama M. Natural decrease of benign metastatic leiomyoma. Chest 2000;117:921-922.

Nadir görülen bir leiyomyom vakası: Retroperitoneal leiyomyom

Year 2014, Volume: 41 Issue: 2, 414 - 417, 01.06.2014
https://doi.org/10.5798/diclemedj.0921.2014.02.0443

Abstract

Primer retroperitoneal leiyomyom, jinekoloji pratiğinde nadir izlenen ve alışılmadık ayırıcı tanılardan biridir. Retroperitoneal leiyomyomanın patogenezi hala belirsizliğini sürdürmektedir. Vakamızdaki 49 yaşındaki nulligravid bayan hasta noktüri, alt batın ağrısı ve büyük bir abdominopelvik kitle şikayeti ile hastanemize başvurdu. Transabdominal ultrasonografi, kontrastlı bilgisayar tomografisi ve manyetik rezonans görüntülemeyi de içeren tanısal girişimler sonucunda hastada 15 cm'lik homojen ve çoklu septasyon gösteren solid pelvik kitle saptandı. Retroperitoneal leioyomyoma ön tanısı tümör eksizyonu ve histopatolojik inceleme sonucunda doğrulandı.

References

  • Cohen DT, Oliva E, Hahn PF, et al. Uterine smooth-muscle tumors with unusual growth patterns: imaging with patho- logic correlation. AJR Am J Roentgenol 2007;188:246-255.
  • Kilpatrick SE, Mentzel T, Fletcher CDM. Leiomyoma of deep soft tissue: A clinicopathologic series. Am J Surg Pat- hol 1994;18:576-582.
  • Fasih N, Prasad Shanbhogue AK, Macdonald DB, et al. Lei- omyomas beyond the uterus: unusual locations, rare mani- festations. Radiographics 2008;28:1931-1948.
  • Kempson RL, Hendrickson MR. Pure mesenchymal neoplas- ms of the uterine corpus: selected problems. Semin Diagn Pathol 1988;5:172-198.
  • Uchida T, Tokumaru T, Kojima H, et al. A case of multiple leiomyomatous lesions of the lung: an analysis of flow cy- tometry and hormone receptors. Surg Today 1992;22:265- 268.
  • Poliquin V, Victory R, Vilos GA. Epidemiology, presentati- on, and management of retroperitoneal leiomyomata: sys- tematic literature review and case report. J Minim Invasive Gynecol 2008;15:152-160.
  • Paal E, Miettinen M. Retroperitoneal leiomyomas: A clini- copathologic and immunohistochemical study of 56 cases with a comparison to retroperitoneal leiomyosarcomas. Am J Surg Pathol 2001;25:1355-1363.
  • Asal N, Koşar PN, Duymuş M, et al. Pelvic magnetic re- sonance imaging in gynecologic masses. Dicle Med J 2011;38:412-420.
  • Takemura G, Takatsu Y, Kaitani K, et al. Metastasizing uteri- ne leiomyoma. A case with cardiac and pulmonary metasta- sis. Pathol Res Pract 1996;192:622-633.
  • Shukunami K, Nishijima K, Kurokawa T, et al. A benign so- litary uterine leiomyoma on the pelvic peritoneum detected long after the hysterectomy for fibroids. J Obstet Gynaecol 2006;26:589.
  • Funakoshi Y, Sawabata N, Takeda S, Hayakawa M, Okumu- ra Y, Maeda H. Pulmonary benign metastasizing leiomyo- ma from the uterus in a postmenopausal woman: Report of a case. Surg Today 2004; 34:55-57.
  • Okolo SO, Gentry CC, Perrett CW, Maclean AB. Familial prevalence of uterine fibroids is associated with distinct cli- nical and molecular features. Hum Reprod 2005;20:2321- 2324.
  • Nayar AC, McAleer EP, Tunick PA, et al. Benign metas- tasizing leiomyomatosis diagnosed by echocardiography. Echocardiography 2002;19:571-572.
  • Sentinelli S, Covello R, Benevolo M, et al. Benign metas- tasizing pulmonary leiomyoma: description of a case and review of the literature. Pathologica 2002;94:253-256.
  • Goyle KK, Moore DF Jr, Garrett C, Goyle V. Benign metas- tasizing leiomyomatosis: case report and review. Am J Clin Oncol 2003;26:473-476.
  • Fukamachi N, Togami S, Iwamoto I, et al. Retroperitoneal uterine leiomyoma occurring 5 years after hysterectomy for fibroids. J Obstet Gynaecol Res 2007;33:878-881.
  • Zaitoon MM: Retroperitoneal parasitic leiomyoma causing unilateral ureteral obstruction. J Urol 1986;135:130-131.
  • Stutterecker D, Umek W, Tunn R, et al. Leiomyoma of the space of Retzius: a report of 2 cases. Am J Obstet Gynecol 2001;185:248-249.
  • Sinha R, Sundaram M, Mahajan C, Sambhus A. Multiple leiomyoma after laparoscopic hysterectomy: Report of two cases. J Minim Invasive Gynecol 2007;14:123-127.
  • Esteban JM, Allen WM, Schaerf RH. Benign metastasizing leiomyoma of the uterus: histologic and immunohistoche- mical characterization of primary and metastatic lesions. Arch Pathol Lab Med 1999;123:960-962.
  • McLeod AJ, Zornoza J, Shirkhoda A. Leiomyosarcoma: computed tomographic findings. Radiology 1984;152:133- 136.
  • Jacobson TZ, Rainey EJ, Turton CW. Pulmonary benign metastasizing leiomyoma: response to treatment with gose- relin. Thorax 1995;50:1225-1226.
  • Arai T, Yasuda Y, Takaya T, Shibayama M. Natural decrease of benign metastatic leiomyoma. Chest 2000;117:921-922.
There are 23 citations in total.

Details

Primary Language Turkish
Journal Section Case Reports
Authors

Yaşam Kemal Akpak This is me

İsmet Gün This is me

Nuri Kaya This is me

Vedat Atay This is me

Publication Date June 1, 2014
Submission Date March 2, 2015
Published in Issue Year 2014 Volume: 41 Issue: 2

Cite

APA Akpak, Y. K., Gün, İ., Kaya, N., Atay, V. (2014). Nadir görülen bir leiyomyom vakası: Retroperitoneal leiyomyom. Dicle Tıp Dergisi, 41(2), 414-417. https://doi.org/10.5798/diclemedj.0921.2014.02.0443
AMA Akpak YK, Gün İ, Kaya N, Atay V. Nadir görülen bir leiyomyom vakası: Retroperitoneal leiyomyom. diclemedj. June 2014;41(2):414-417. doi:10.5798/diclemedj.0921.2014.02.0443
Chicago Akpak, Yaşam Kemal, İsmet Gün, Nuri Kaya, and Vedat Atay. “Nadir görülen Bir Leiyomyom vakası: Retroperitoneal Leiyomyom”. Dicle Tıp Dergisi 41, no. 2 (June 2014): 414-17. https://doi.org/10.5798/diclemedj.0921.2014.02.0443.
EndNote Akpak YK, Gün İ, Kaya N, Atay V (June 1, 2014) Nadir görülen bir leiyomyom vakası: Retroperitoneal leiyomyom. Dicle Tıp Dergisi 41 2 414–417.
IEEE Y. K. Akpak, İ. Gün, N. Kaya, and V. Atay, “Nadir görülen bir leiyomyom vakası: Retroperitoneal leiyomyom”, diclemedj, vol. 41, no. 2, pp. 414–417, 2014, doi: 10.5798/diclemedj.0921.2014.02.0443.
ISNAD Akpak, Yaşam Kemal et al. “Nadir görülen Bir Leiyomyom vakası: Retroperitoneal Leiyomyom”. Dicle Tıp Dergisi 41/2 (June 2014), 414-417. https://doi.org/10.5798/diclemedj.0921.2014.02.0443.
JAMA Akpak YK, Gün İ, Kaya N, Atay V. Nadir görülen bir leiyomyom vakası: Retroperitoneal leiyomyom. diclemedj. 2014;41:414–417.
MLA Akpak, Yaşam Kemal et al. “Nadir görülen Bir Leiyomyom vakası: Retroperitoneal Leiyomyom”. Dicle Tıp Dergisi, vol. 41, no. 2, 2014, pp. 414-7, doi:10.5798/diclemedj.0921.2014.02.0443.
Vancouver Akpak YK, Gün İ, Kaya N, Atay V. Nadir görülen bir leiyomyom vakası: Retroperitoneal leiyomyom. diclemedj. 2014;41(2):414-7.