Neurourological complications in patients with myelodisplasia

Year 2014, Volume: 41 Issue: 1, 234 - 237, 01.03.2014

Sümeyye Çoruh Kaplan Cüneyt Göçmez Mansur Dağgülli

https://doi.org/10.5798/diclemedj.0921.2014.01.0409

Abstract

Spina bifida yaşamla bağdaşan konjenital anomaliler arasında sık rastlanılan patolojilerdendir. Embriyolojik dönemde nöral tüpün kapanma defektleri açık ya da kapalı spinal disrafizmle sonuçlanır. Günümüzde nöroşirurjikal tekniklerin ilerlemesiyle hastaların multidisipliner takibi, yaşam kaliteleri açısından önem kazanmıştır. Ürolojik komplikasyonların önlenmesi ve tespit edilmesi bakımından da bazı yaklaşımlar standardize edilmiştir. Olguların uzun dönem takibinde nöroşirurjikal açıdan prognozun yanı sıra eşlik edebilen tüm patolojilerin akılda tutulması ve bu amaçla hastaya yön gösterilmesi önemlidir. Bu yazıdaki amaç Spina bifida hastalarında mevcut olabilecek ürolojik problemleri ve bunlarla ilgili son çalışmaları gözden geçirmektir.

Keywords

Spina bifida, spinal disrafizm, üriner inkontinans, nörojenik mesane

Neurourological complications in patients with myelodisplasia

Abstract

Spina bifida is a frequently seen congenital anomaly which is compatible with life. During the embryological period the defects in the closure of neural tube leads to open or closed spinal dysraphism. At the present day with the improving neurochirurgical techniques, the patients multidisciplinary follow-ups became important as a matter of the health quality. To prevent and to determine the urological complications some approaches became standardized. In the long term period all accompanying pathologies have to be beared in the mind in addition to neurosurgical prognosis and the patients must have to be guided indeed. The aim of this review is to look over the urological problems and the last studies about these problems in spina bifida patients.

Keywords

Spina bifida, spinal dysraphism, urinary incontinence, neurogenic bladder

References

• Tunçbilek E. Türkiye’deki yüksek nöral tüp defekti sıklığı ve önlemek için yapılabilecekler. Çocuk Sağlığı ve Hastalıkla- rı Dergisi 2004:47;79-84
• Akalan N. Spinal dysraphism. In: Behrooz A. Akbarnia MD, Muharrem Yazici MD, MD GHT, editors. The Growing Spine Management of Spinal Disorders in Young Children 2011;269-279
• Tarcan T, Bauer S: Neuro-Urological Management of the Neuropathic Bladder in Children with Myelodysplasia. Özek MM, Cinalli G, Maixner WJ (eds), Spina Bifida. Springer-Verlag, Italy 2008:381-394
• Yücel S, Ertuğrul A, İlker Y, et al The incidence of unde- scended testis in children with myelodisplasia and its rela- tion with spinal level of the lesion .Turk J Urol 2000;26:328- 331
• Mc Guire EJ, Bloom DA, Ritchey ML. Myelodysplasia. Probl Urol 1993;7:1-14
• Tarcan T, Önol FF, İlker Y, et al. Early primary repair im- proves the neurourological prognosis significantly in in- fants with myelomeningocele. J Urol 2006;176:1161-1165.
• Management of Myelomeningocele Trial http://clinicaltrials. gov; 2009; NCT00060606
• Clayton DB, Brock III J W. The Urologist’s Role in the Man- agement of Spina Bifida: A Continuum of Care. Urology 2010;76:32-38.
• Stoneking BJ, Brock III JW, Pope IV JC, Adams MC. Early evolution of bladder emptying after myelomeningocele clo- sure. Urology 2001;58:767-771.
• Tarcan T, Önol FF, İlker Y, et al. Does surgical release of secondary spinal cord tethering improve the prognosis of neurogenic bladder in children with myelomeningocele? J Urol 2006;176:1601-1606.
• Lemelle JL, Guillemin F, Aubert D, et al. A multicenter evaluation of urinary incontinence management and out- come in spina bifida. J Urol 2006;175:208-212.
• Campbell JB, Moore KN, Voaklander DC, Mix LW. Com- plications associated with clean intermittent catheterization in children with spina bifida. J Urol 2004;171:2420-2422.
• Metcalfe PD, Cain MP, Kaefer M, et al. What is the need for additional bladder surgery after bladder augmentation in childhood. J Urol 2006;176:1801-1805.
• Vaidyanathan S, Selmi F, Soni B, et al. Pyonephrosis and urosepsis in a 41-year old patient with spina bifida: Case report of a preventable death. Patient Saf Surg 2012;6:10.
• Lapides J, Diokno AC, Silber SJ, Lowe BS. Clean, inter- mittent self-catheterization in the treatment of urinary tract disease. Trans Am Assoc Genitourin Surg 1971;63:92-96.
• Dik P, Klijn AJ, van Gool JD, de Jong-de Vos van Steenwijk CC, de Jong TP. Early start to therapy preserves kidney function in spina bifida patients. Eur Urol 2006;49:908-913.
• Lindehall B, Abrahamsson K, Hjalmas K, et al. Compli- cations of clean intermittent catheterization in boys and young males with neurogenic bladder dysfunction. J Urol 2004;172:1686-1688.
• Wilson R, Lewis SA, Dicianno BE. Targeted preventive care may be needed for adults with congenital spine anoma- lies. PM&R 2011;3:730-738.