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Comparison of Thrombolytic and Primer Percutaneous Coronary Intervention Treatment Methods Used in Acute Myocardial Infarction in Terms of Myocardial Performance Index

Year 2008, Volume: 35 Issue: 2, 114 - 119, 01.06.2008

Abstract

Coronary reperfusion on acute myocardial infarction can be obtained by administation of thrombolytic drugs intravenously or by primer percutaneous coronary intervention in terms of mechanically. In this study, our aim was to compare the effects of both of two reperfusion methods on myocardial performance index which is used as a prognostic indicator in acute myocardial infarction in recent years. The 100 patients who are diagnosed as myocardial infarction and underwent reperfusion therapy were included in this study. We applied primer percutaneous coronary intervention to 29 of patients and thrombolytic therapy to 71 of patients. In primer percutaneous coronary intervention applied group, myocardial performance index values were lower than the thrombolytic therapy administered group. As a conclusion, it is suggested that myocardial performance index which is used as a prognostic indicator in acute myocardial infarction can be affected by reperfusionstrategies and primer percutaneous coronary intervention is much more effective approach than thrombolytic therapy in respect to achieve better myocardial performance index values.

References

  • Franzosi MG, Santoro E, De Vita C, et Sopravvivenza nell'Infarto-1 study. The GISSI Investigators. Circulation, 1998; 98: 2659- 2665.
  • Dauerman HL, Lessard D, Yarzebski J, et al. Ten-year trends in the incidence, treatment and outcome of Q-wave myocardial infarction. Am J Cardiol, 2000; 86: 730-735.
  • Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet, 2003; 361: 13-20.
  • Tei C, Nishimura RA, Seward JB, Tajik
  • LaCorte JC, Cabreriza SE, Rabkin DG, et al. Correlation of the Tei index with invasive measurements of ventricular function in a porcine model. J Am Soc Echocardiogr, 2003; 16: 442-447.
  • Tei C, Dujardin KS, Hodge DO, et al. Doppler index combining systolic and diastolic myocardial performance: clinical value in cardiac amyloidosis. J Am Coll Cardiol, 1996; 28: 658-664.
  • Tei C, Ling LH, Hodge DO, et al. New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function--a study in normals and dilated cardiomyopathy. J Cardiol, 1995; 26: 357-366.
  • Lax JA, Bermann AM, Cianciulli TF, et al. Estimation of the ejection fraction in patients with myocardial infarction obtained from the combined index of systolic and diastolic left ventricular function: a new method. J Am Soc Echocardiogr, 2000; 13: 116-123.
  • Arnlov J, Lind L, Andren B, et al. A Doppler-derived index of combined left ventricular systolic and diastolic function is an independent predictor of cardiovascular mortality in elderly men. American Heart Journal, 2005: 149; 902-907.
  • Moller JE, Egstrup K, Kober L, et al. Prognostic importance of systolic and diastolic function after acute myocardial infarction. American Heart Journal, 2003; 145: 147-153.
  • Nishimura RA, Tajik AJ, Shub C, et al. Role of two-dimensional echocardiography in the prediction of in-hospital complications after acute myocardial infarction. J Am Coll Cardiol, 1984; 4: 1080-1087.
  • Gibson RS, Bishop HL, Stamm RB, et al. Value of early two-dimensional echocardiography in patients with acute myocardial infarction. Am J Cardiol, 1982; 49: 1110-1119.
  • Moller JE, Poulsen SH, Egstrup K. Effect of preload alternations on a new Doppler echocardiographic index of combined systolic and diastolic performance. J Am Soc Echocardiogr, 1999; 12: 1065-1072.
  • A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute miyocardial infarction. The Global Use of Strategies to Open Occluded Coronary Aretries in Acute Coronary Syndromes (GUSTO2b) Angioplasty Substudy Investigators. N Engl J Med, 1997; 336: 1621- 1628.
  • Weavar WD, Simes RJ, Betriu A, et al. Comparison of primary coronary angioplasty and intarvenous thrombolytic therapy for acute myocardial infarction: quantitative review. JAMA, 1997; 278: 2093-2098.
  • Keeley E, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet, 2003; 361: 13-20.
  • Andersen HR, Nielsen TT, Vesterlund T, et al. Danish multicenter randomized study on fibrinolytic therapy versus acute coronary angioplasty in acute myocardial infarction: rationale and design of the DANish trial in Acute Myocardial Infarction-2 (DANAMI-II ). Am Heart J, 2003; 146: 234-241.
  • Andersen HR, Nielsen TT, Rasmussen K, et al. A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. N Engl J Med, 2003; 349: 733-742.
  • Bonnefoy E, Lapostolle F, Leizorovicz A, et al. Primary angioplasty versus prehospital fibrinolysis in acute myocardial infarction: a randomised study. Lancet, 2002; 360: 825-829.
  • Wilson SH, Bell MR, Rihal CS, et al. Infarct artery reocclusion after primary angioplasty, stent placement, and thrombolytic therapy for acute myocardial infarction. Am Heart J, 2001; 141: 704-710.

Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması

Year 2008, Volume: 35 Issue: 2, 114 - 119, 01.06.2008

Abstract

Akut miyokard infarktüsünde koroner reperfüzyonun sağlanması, farmakolojik olarak intravenöz yoldan uygulanan trombolitik ilaçlar ya da mekanik olarak primer perkutan koroner girişim ile sağlanabilir. Biz de çalışmamızda her iki reperfüzyon yaklaşımını, son yıllarda akut miyokard infarktüsünde prognostik gösterge olarak kullanılan, miyokardiyal performans indeksine etkileri açısından karşılaştırmayı hedefledik. Çalışmamıza akut miyokard infarktüsü tanısı alıp, reperfüzyon tedavisi gören 100 hastayı dahil ettik. Bunlardan 29 tanesine primer perkütan koroner girişim, 71 tanesine trombolitik tedavi uyguladık. Çalışmanın sonucunda primer perkütan koroner girişim uygulanan gruptaki miyokardiyal performans indeksi değerlerini, trombolitik tedavi uygulanan gruba göre daha düşük bulduk. Sonuç olarak akut miyokard infarktüsünde prognostik gösterge olarak kullanılan miyokardiyal performans indeksinin, reperfüzyon stratejilerinden etkilendiğini ve primer perkütan koroner girişim yönteminin trombolitik tedaviye göre daha iyi miyokardiyal performans indeksi değerleri sağladığını söyleyebiliriz.

References

  • Franzosi MG, Santoro E, De Vita C, et Sopravvivenza nell'Infarto-1 study. The GISSI Investigators. Circulation, 1998; 98: 2659- 2665.
  • Dauerman HL, Lessard D, Yarzebski J, et al. Ten-year trends in the incidence, treatment and outcome of Q-wave myocardial infarction. Am J Cardiol, 2000; 86: 730-735.
  • Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet, 2003; 361: 13-20.
  • Tei C, Nishimura RA, Seward JB, Tajik
  • LaCorte JC, Cabreriza SE, Rabkin DG, et al. Correlation of the Tei index with invasive measurements of ventricular function in a porcine model. J Am Soc Echocardiogr, 2003; 16: 442-447.
  • Tei C, Dujardin KS, Hodge DO, et al. Doppler index combining systolic and diastolic myocardial performance: clinical value in cardiac amyloidosis. J Am Coll Cardiol, 1996; 28: 658-664.
  • Tei C, Ling LH, Hodge DO, et al. New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function--a study in normals and dilated cardiomyopathy. J Cardiol, 1995; 26: 357-366.
  • Lax JA, Bermann AM, Cianciulli TF, et al. Estimation of the ejection fraction in patients with myocardial infarction obtained from the combined index of systolic and diastolic left ventricular function: a new method. J Am Soc Echocardiogr, 2000; 13: 116-123.
  • Arnlov J, Lind L, Andren B, et al. A Doppler-derived index of combined left ventricular systolic and diastolic function is an independent predictor of cardiovascular mortality in elderly men. American Heart Journal, 2005: 149; 902-907.
  • Moller JE, Egstrup K, Kober L, et al. Prognostic importance of systolic and diastolic function after acute myocardial infarction. American Heart Journal, 2003; 145: 147-153.
  • Nishimura RA, Tajik AJ, Shub C, et al. Role of two-dimensional echocardiography in the prediction of in-hospital complications after acute myocardial infarction. J Am Coll Cardiol, 1984; 4: 1080-1087.
  • Gibson RS, Bishop HL, Stamm RB, et al. Value of early two-dimensional echocardiography in patients with acute myocardial infarction. Am J Cardiol, 1982; 49: 1110-1119.
  • Moller JE, Poulsen SH, Egstrup K. Effect of preload alternations on a new Doppler echocardiographic index of combined systolic and diastolic performance. J Am Soc Echocardiogr, 1999; 12: 1065-1072.
  • A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute miyocardial infarction. The Global Use of Strategies to Open Occluded Coronary Aretries in Acute Coronary Syndromes (GUSTO2b) Angioplasty Substudy Investigators. N Engl J Med, 1997; 336: 1621- 1628.
  • Weavar WD, Simes RJ, Betriu A, et al. Comparison of primary coronary angioplasty and intarvenous thrombolytic therapy for acute myocardial infarction: quantitative review. JAMA, 1997; 278: 2093-2098.
  • Keeley E, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet, 2003; 361: 13-20.
  • Andersen HR, Nielsen TT, Vesterlund T, et al. Danish multicenter randomized study on fibrinolytic therapy versus acute coronary angioplasty in acute myocardial infarction: rationale and design of the DANish trial in Acute Myocardial Infarction-2 (DANAMI-II ). Am Heart J, 2003; 146: 234-241.
  • Andersen HR, Nielsen TT, Rasmussen K, et al. A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. N Engl J Med, 2003; 349: 733-742.
  • Bonnefoy E, Lapostolle F, Leizorovicz A, et al. Primary angioplasty versus prehospital fibrinolysis in acute myocardial infarction: a randomised study. Lancet, 2002; 360: 825-829.
  • Wilson SH, Bell MR, Rihal CS, et al. Infarct artery reocclusion after primary angioplasty, stent placement, and thrombolytic therapy for acute myocardial infarction. Am Heart J, 2001; 141: 704-710.
There are 20 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Mahir Çiftçi This is me

Aziz Karabulut This is me

Hasan Akkoç This is me

Publication Date June 1, 2008
Submission Date March 2, 2015
Published in Issue Year 2008 Volume: 35 Issue: 2

Cite

APA Çiftçi, M., Karabulut, A., & Akkoç, H. (2008). Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması. Dicle Tıp Dergisi, 35(2), 114-119.
AMA Çiftçi M, Karabulut A, Akkoç H. Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması. diclemedj. June 2008;35(2):114-119.
Chicago Çiftçi, Mahir, Aziz Karabulut, and Hasan Akkoç. “Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması”. Dicle Tıp Dergisi 35, no. 2 (June 2008): 114-19.
EndNote Çiftçi M, Karabulut A, Akkoç H (June 1, 2008) Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması. Dicle Tıp Dergisi 35 2 114–119.
IEEE M. Çiftçi, A. Karabulut, and H. Akkoç, “Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması”, diclemedj, vol. 35, no. 2, pp. 114–119, 2008.
ISNAD Çiftçi, Mahir et al. “Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması”. Dicle Tıp Dergisi 35/2 (June 2008), 114-119.
JAMA Çiftçi M, Karabulut A, Akkoç H. Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması. diclemedj. 2008;35:114–119.
MLA Çiftçi, Mahir et al. “Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması”. Dicle Tıp Dergisi, vol. 35, no. 2, 2008, pp. 114-9.
Vancouver Çiftçi M, Karabulut A, Akkoç H. Akut Miyokard İnfarktüsünde Kullanılan Trombolitik Ve Primer Perkütan Koroner Girişim Tedavi Yöntemlerinin Miyokardiyal Performans İndeksine Etkileri Açısından Karşılaştırılması. diclemedj. 2008;35(2):114-9.