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Effect of left bundle branch block on TIMI frame count

Year 2010, Volume: 37 Issue: 2, 125 - 128, 01.06.2010

Abstract

Aim: Left bundle branch block is an independent risk fac­tor for cardiac mortality. In this study we aimed to evalu­ate coronary blood flow with TIMI frame count in patients with left bundle branch block and angiographically proven normal coronary arteries. Materials and methods: We retrospectively studied 17 patients with left bundle branch block and as a control group 16 patients without left bundle branch block. All pa­tients had angiographically proven normal coronary arter­ies. Left bundle branch block was determined according to standart electrocardiographic criteria. The TIMI frame count was measured for each major coronary artery in each patient. Results: TIMI frame count for left anterior descending coronary artery was found to be significantly higher in pa­tients with left bundle branch block compared with patients without left bundle branch block (35.4±16.7 ve 23.8±4.5, p=0.012). TIMI frame counts for circumflex and right coro­nary arteries were similar in patients with and without left bundle branch block (TIMI frame count for circumflex ar­tery: 32.4±15.4 ve 27.7±7.6, p=0.275; TIMI frame count for right coronary artery: 31.9±9.6 ve 27.0±8.6, p=0.141). Conclusion: We have found that TIMI frame count for left anterior descending coronary artery was higher in patients with left bundle branch block compared with patients without left bundle branch block whereas there were no difference for TIMI frame counts for circumflex and right coronary arteries. Impaired coronary blood flow in left anterior descending artery may help to explain the sintigraphic perfusion defects in septum of patients with left bundle branch block.

References

  • Casiglia E, Spolaore P, Ginocchio G, et al. Mortality in rela- tion to Minnesota code items in elderly subjects. Sex-relat- ed differences in a cardiovascular study in the elderly. Jpn Heart J 1993;34:567-77.
  • Baldasseroni S, Opasich C, Gorini M, et al. Left bundle- branch block is associated with increased 1-year sudden and total mortality rate in 5517 outpatients with congestive heart failure: a report from the Italian network on conges- tive heart failure. Am Heart J 2002;143:398-405.
  • Schneider JF, Thomas HE Jr, Kreger BE, et al. Newly ac- quired left bundle-branch block: the Framingham study. Ann Intern Med 1979;90:303-10.
  • Tandogan I, Yetkin E, Ileri M, et al. Diagnosis of coronary artery disease with Tl-201 SPECT in patients with left bun- dle branch block: importance of alternative interpretation approaches for left anterior descending coronary lesions. Angiology 2001;52:103-8.
  • Hirzel HO, Senn M, Nuesch K, et al. Thallium-201 scintig- raphy in complete left bundle branch block. Am J Cardiol 1984;53:764-9.
  • Larcos G, Gibbons RJ, Brown ML. Diagnostic accuracy of exercise thallium-201 single-photon emission computed to- mography in patients with left bundle branch block. Am J Cardiol 1991;68:756–60.
  • Vaduganathan P, He ZX, Raghavan C, Mahmarian JJ, Verani MS. Detection of left anterior descending coronary artery stenosis in patients with left bundle branch block: exer- cise, adenosine or dobutamine imaging? J Am Coll Cardiol 1996;28:543-50.
  • Grines CL, Bashore TM, Boudoulas H, Olson S, Shafer P, Wooley CF. Functional abnormalities in isolated left bundle branch block: the effect of interventricular asynchrony. Cir- culation 1989;79:845-53.
  • Ono S, Nohara R, Kambara H, Okuda K, Kawai C. Regional myocardial perfusion and glucose metabolism in experi- mental left bundle branch block. Circulation 1992;85:1125- 31.
  • Youn HJ, Park CS, Cho EJ, et al. Left bundle branch block disturbs left anterior descending coronary artery flow: study using transthoracic Doppler echocardiography. J Am Soc Echocardiogr 2005;18:1093-8.
  • Skalidis EI, Kochiadakis GE, Koukouraki SI, Parthenakis FI, Karkavitsas NS, Vardas PE. Phasic coronary flow pat- tern and flow reserve in patients with left bundle branch block and normal coronary arteries. J Am Coll Cardiol 1999;33:1338-46.
  • Gibson CM, Cannon CP, Daley WL, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 1996;93:879-88.
  • Orzan F, Garcia E, Mathur VS, Hall RJ. Is the treadmill exercise test useful for evaluating coronary artery disease in patients with complete left bundle branch block? Am J Cardiol 1978;42:36-40.
  • Lebtahi NE, Stauffer JC, Delaloye AB. Left bundle branch block and coronary artery disease: accuracy of dipyridamo- le thallium-201 single-photon emission computed tomogra- phy in patients with exercise anteroseptal perfusion defects. J Nucl Cardiol 1997;4:266-73.
  • Biceroglu S, Yildiz A, Bayata S, Yesil M, Postaci N. Is there an association between left bundle branch block and coro- nary slow flow in pateints with normal coronary arteries? Angiology 2008;58:685-8.

Sol dal bloğunun TIMI kare sayısı üzerine etkisi

Year 2010, Volume: 37 Issue: 2, 125 - 128, 01.06.2010

Abstract

Amaç: Sol dal bloğu, kardiyak mortalite için bağımsız bir risk faktörüdür. Bu çalışmadaki amacımız anjiyografik ola­rak normal koroner arterlere sahip ve sol dal bloğu olan hastalarda koroner kan akımını TIMI kare sayısı ile de­ğerlendirmektir. Gereç ve yöntemler: Bu retrospektif çalışmaya elektro­kardiyografisinde sol dal bloğu olan 17 hasta ve kontrol grubu olarak sol dal bloğu olmayan 16 hasta dahil edildi. Tüm hastalar anjiyografik olarak normal koroner arterlere sahipti. Sol dal bloğu tanısı standart elektrokardiyografikriterlerine göre konuldu. Hastalarda her üç koroner da­mar için TIMI kare sayısı ölçüldü. Bulgular: Sol dal bloğu olan hastalarda sol ön inen ko­roner arter için düzeltilmiş TIMI kare sayısı sol dal blo­ğu olmayan hastalara göre istatistiksel olarak anlamlı derecede daha yüksek bulundu (35.4±16.7 ve 23.8±4.5, p=0.012). Sirkumfleks ve sağ koroner arterler için TIMI kare sayılarının sol dal bloğu olan ve olmayan hastalarda farklı olmadığı görüldü (sirkumfleks arter için TIMI kare sayısı: 32.4±15.4 ve 27.7±7.6, p=0.275; sağ koroner arter için TIMI kare sayısı: 31.9±9.6 ve 27.0±8.6, p=0.141). Sonuç: Çalışmamızda sol ön inen koroner arterde TIMI kare sayısı sol dal bloğu olan hastalarda sol dal bloğu ol­mayan hastalara göre daha yüksek bulunurken, sirkumf­leks ve sağ koroner arterler için fark izlenmemiştir. Sol ön inen arterde koroner kan akımının bozulmuş olması sol dal bloğu olan hastalarda septumda izlenen sintigrafik perfüzyon defektlerini açıklamaya yardım edebilir.

References

  • Casiglia E, Spolaore P, Ginocchio G, et al. Mortality in rela- tion to Minnesota code items in elderly subjects. Sex-relat- ed differences in a cardiovascular study in the elderly. Jpn Heart J 1993;34:567-77.
  • Baldasseroni S, Opasich C, Gorini M, et al. Left bundle- branch block is associated with increased 1-year sudden and total mortality rate in 5517 outpatients with congestive heart failure: a report from the Italian network on conges- tive heart failure. Am Heart J 2002;143:398-405.
  • Schneider JF, Thomas HE Jr, Kreger BE, et al. Newly ac- quired left bundle-branch block: the Framingham study. Ann Intern Med 1979;90:303-10.
  • Tandogan I, Yetkin E, Ileri M, et al. Diagnosis of coronary artery disease with Tl-201 SPECT in patients with left bun- dle branch block: importance of alternative interpretation approaches for left anterior descending coronary lesions. Angiology 2001;52:103-8.
  • Hirzel HO, Senn M, Nuesch K, et al. Thallium-201 scintig- raphy in complete left bundle branch block. Am J Cardiol 1984;53:764-9.
  • Larcos G, Gibbons RJ, Brown ML. Diagnostic accuracy of exercise thallium-201 single-photon emission computed to- mography in patients with left bundle branch block. Am J Cardiol 1991;68:756–60.
  • Vaduganathan P, He ZX, Raghavan C, Mahmarian JJ, Verani MS. Detection of left anterior descending coronary artery stenosis in patients with left bundle branch block: exer- cise, adenosine or dobutamine imaging? J Am Coll Cardiol 1996;28:543-50.
  • Grines CL, Bashore TM, Boudoulas H, Olson S, Shafer P, Wooley CF. Functional abnormalities in isolated left bundle branch block: the effect of interventricular asynchrony. Cir- culation 1989;79:845-53.
  • Ono S, Nohara R, Kambara H, Okuda K, Kawai C. Regional myocardial perfusion and glucose metabolism in experi- mental left bundle branch block. Circulation 1992;85:1125- 31.
  • Youn HJ, Park CS, Cho EJ, et al. Left bundle branch block disturbs left anterior descending coronary artery flow: study using transthoracic Doppler echocardiography. J Am Soc Echocardiogr 2005;18:1093-8.
  • Skalidis EI, Kochiadakis GE, Koukouraki SI, Parthenakis FI, Karkavitsas NS, Vardas PE. Phasic coronary flow pat- tern and flow reserve in patients with left bundle branch block and normal coronary arteries. J Am Coll Cardiol 1999;33:1338-46.
  • Gibson CM, Cannon CP, Daley WL, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 1996;93:879-88.
  • Orzan F, Garcia E, Mathur VS, Hall RJ. Is the treadmill exercise test useful for evaluating coronary artery disease in patients with complete left bundle branch block? Am J Cardiol 1978;42:36-40.
  • Lebtahi NE, Stauffer JC, Delaloye AB. Left bundle branch block and coronary artery disease: accuracy of dipyridamo- le thallium-201 single-photon emission computed tomogra- phy in patients with exercise anteroseptal perfusion defects. J Nucl Cardiol 1997;4:266-73.
  • Biceroglu S, Yildiz A, Bayata S, Yesil M, Postaci N. Is there an association between left bundle branch block and coro- nary slow flow in pateints with normal coronary arteries? Angiology 2008;58:685-8.
There are 15 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Ayşe Saatcı Yaşar This is me

Nurcan Başar This is me

İsa Öner Yüksel This is me

Ahmet Kasapkara This is me

Hatice Tolunay This is me

Mehmet Bilge This is me

Publication Date June 1, 2010
Submission Date March 2, 2015
Published in Issue Year 2010 Volume: 37 Issue: 2

Cite

APA Yaşar, A. S., Başar, N., Yüksel, İ. Ö., Kasapkara, A., et al. (2010). Sol dal bloğunun TIMI kare sayısı üzerine etkisi. Dicle Tıp Dergisi, 37(2), 125-128.
AMA Yaşar AS, Başar N, Yüksel İÖ, Kasapkara A, Tolunay H, Bilge M. Sol dal bloğunun TIMI kare sayısı üzerine etkisi. diclemedj. June 2010;37(2):125-128.
Chicago Yaşar, Ayşe Saatcı, Nurcan Başar, İsa Öner Yüksel, Ahmet Kasapkara, Hatice Tolunay, and Mehmet Bilge. “Sol Dal bloğunun TIMI Kare sayısı üzerine Etkisi”. Dicle Tıp Dergisi 37, no. 2 (June 2010): 125-28.
EndNote Yaşar AS, Başar N, Yüksel İÖ, Kasapkara A, Tolunay H, Bilge M (June 1, 2010) Sol dal bloğunun TIMI kare sayısı üzerine etkisi. Dicle Tıp Dergisi 37 2 125–128.
IEEE A. S. Yaşar, N. Başar, İ. Ö. Yüksel, A. Kasapkara, H. Tolunay, and M. Bilge, “Sol dal bloğunun TIMI kare sayısı üzerine etkisi”, diclemedj, vol. 37, no. 2, pp. 125–128, 2010.
ISNAD Yaşar, Ayşe Saatcı et al. “Sol Dal bloğunun TIMI Kare sayısı üzerine Etkisi”. Dicle Tıp Dergisi 37/2 (June 2010), 125-128.
JAMA Yaşar AS, Başar N, Yüksel İÖ, Kasapkara A, Tolunay H, Bilge M. Sol dal bloğunun TIMI kare sayısı üzerine etkisi. diclemedj. 2010;37:125–128.
MLA Yaşar, Ayşe Saatcı et al. “Sol Dal bloğunun TIMI Kare sayısı üzerine Etkisi”. Dicle Tıp Dergisi, vol. 37, no. 2, 2010, pp. 125-8.
Vancouver Yaşar AS, Başar N, Yüksel İÖ, Kasapkara A, Tolunay H, Bilge M. Sol dal bloğunun TIMI kare sayısı üzerine etkisi. diclemedj. 2010;37(2):125-8.