Hipertiroid hastalarda tedavi öncesi ve sonrası lipid profili ile homosistein, leptin, fibrinojen ve C-reaktif protein düzeyleri

Year 2010, Volume: 37 Issue: 1, 1 - 7, 01.03.2010

Emine Sütken Aysen Akalın Filiz Özdemir Ömer Çolak

Abstract

Amaç: Bu çalışma hipertiroidizmli hastalarda tiroid hor­monlarının lipid profilini, eritrosit sedimentasyon hızını (ESR), serum total homosistein (t-hcy), leptin, fibrinojen ve C-reaktif protein (CRP) düzeylerini etkileyip etkileme­diğini tespit etmek için tasarlanmıştır. Gereç ve yöntem: Bu çalışma yaş ortalaması 41.8±2.4 yıl arasında olan 23 hipertiroid (3 erkek/ 20 kadın) ile gerçekleştirildi. Homosistein, leptin, fibrinojen, CRP, to­tal kolesterol (TK), yüksek dansiteli lipoprotein kolesterol (HDL-K), düşük dansiteli lipoprotein kolestrol (LDL-K)\'ün serum düzeyleri ve ESR ölçüldü ve vücut kütle indeksi (BMI) tedaviden önce ve sonra hesaplandı. Bulgular: Hipertiroid hastalarının tedavi öncesi t-hcy, TC, LDL-Kolesterol, HDL-Kolesterol düzeyleri ve BMI tedavi sonrası düzeylerden daha düşüktü (tüm değişkenler için, p

Keywords

Hipertiroidi, homosistein, leptin, lipid profii, tedavi

Lipid profile and levels of homocysteine, leptin, fibrinogen and C-reactive protein in hyperthyroid patients before and after treatment

Abstract

Objectives: The present study was carried out to deter­mine whether thyroid hormones affect lipid profile and levels of erithrocyte sedimentation rate (ESR), serum total homocysteine (t-hcy), leptin, fibrinogen, C-reactive protein (CRP in patients with hyperthyroidism. Materials and methods: This study was carried out on 23 hyperthroid subjects (3 men / 20 women, mean age 41.8 ± 2.4 years). Serum levels of homocysteine, leptin, fibrinogen, CRP, total cholesterol (TC), high-density lipo­protein cholesterol (HDL-C), low-density lipoprotein cho­lesterol (LDL-C) and ESR were measured and body mass index (BMI) were calculated before and after treatment of hyperthyroidism. Results: Pretreatment t-hcy, TC, LDL-C, HDL-C levels and BMI of patients were significantly lower than those of the post-treatment (p

Keywords

Hyperthyroidism, homocysteine, leptin, lipid profile, treatment

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