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Involvement of bilateral lacrimal gland in systemic Hodgkin disease

Year 2010, Volume: 37 Issue: 1, 67 - 70, 01.03.2010

Abstract

Five percent (5%) of lacrimal gland tumors are originated from lymphoid tissue. In one type of Hodgkin disease which is abounding in lymphocytes, involvement of lacri­mal gland is a rather rare entity. A 48 – year old woman who had swollen both eyelids, applied to department of oculoplasty in our clinic. At in­spection, when eyelids were rotated, a mass was seen at the region which fits to bilateral lacrimal gland area. Magnetic resonance imaging of the orbita showed a well-demarcated soft tissue mass without invade adjacent structure in the supero-lateral aspect of the bilateral orbit, occupying lacrimal gland. Lymphadenopathies in abdomi­nal, cervical, inguinal, axillary regions have been found in systemic scanning. Biopsy of lacrimal gland and axillary lymphadenopahty were performed and histopathological examination revealed the diagnosis as Hodgkin disease abounding in lymphocytes. The patient was underwent four cure chemotherapy. Clinical and tomographic find­ings were found to be regressed after treatment.

References

  • Bairey O, Kremer I, Rakowsky E, Hadar H, Shaklai M.Orbital and adnexal involvement in systemic Non-Hodgkin’s lym- phoma. Cancer 1994;73:2395-2399.
  • Barışta İ, Güllü İ, Akpek B, Demirkazık F, Ayhan A, Baltalı E, Tekuzman G, Fırat D: Non-Hodgkin lenfomalarda oküler ve orbital tutulum. T Oft Gaz 1994;24:392-395.
  • Liang R, Loke SL, Chiu E.A clinico-pathological cases of Non-Hodgkin lymphoma involving in orbit. Acta Oncol 1991;30:335-338.
  • Jenkins C, Rose GE, Bunce C, Cree I, Norton A, Plowman PN, Moseley I, Wright JE. Clinical features associated with survival of patients with lymphoma of the ocular adnexa. Eye 2003;17:809-820.
  • Crawford JB. Conjunctival tumours. In: Tasman W, Jaeger EA, eds. Duane’s clinical ophthalmology, Vol. 4. Philadel- phia: JB Lippincott, 1994;10:2-10:6.
  • Klapper SR, Jordan DR, McLeish W, Pelletier C. Unilateral proptosis in an immunocompetant man as the initial clinical manifestation of systemic Hodgkin disease. Ophthalmol- ogy 1999;106:338-341.
  • Rosenburg PA, Kaplan HS. Evidence for an orderly pro- gression in the spread of Hodgkin’s disease. Cancer Res 1996;26:1225-31.
  • Fitzpatrick PJ, Macko S. Lymphoreticular tumours of the or- bit. Int J Radiation Oncol Biol Phys 1984;10:333-340.
  • Vaughan GJ, Dortzbach RK. Eyelid malignancies. In: Yanoff M, Duker JS. Ophthalmology. Mosby. 1999;7:12-16.
  • Tiwari RM. Lymphosarcoma of lacrimal gland. Laryngo- scope 1971;81:1519-1523.

Sistemik Hodgkin hastalığında iki taraflı lakrimal bez tutulumu

Year 2010, Volume: 37 Issue: 1, 67 - 70, 01.03.2010

Abstract

Lakrimal gland tümörlerinin %5\'i lenfoid dokudan köken alır. Hodgkin Hastalığının lenfositten zengin tipinde lakri­mal gland tutulumu ise oldukça nadir bir durumdur. Kliniğimiz okuloplasti birimine başvuran, 48 yaşındaki kadın hastanın şikayeti her iki göz kapağında şişlik idi. Muayenede kapaklar çevrildiğinde bilateral lakrimal glan­da uyan bölgede kitle görüldü. Orbita manyetik rezonans görüntülemesinde bilateral bulbus okuli süperolateralin­de, lakrimal bezi tutan, sınırları belirgin, komşu yapıla­ra invazyon göstermeyen, yumuşak doku kitlesi izlendi. Sistemik taramada abdominal, servikal, inguinal, aksiller bölgelerde lenfadenopatilere rastlandı. Lakrimal gland ve aksiller lenf nodu biyopsileri yapıldı. Histopatolojik tanı lenfositten zengin Hodgkin Hastalığı olarak rapor edildi. Hastaya dört kür kemoterapi verildi. Tedavi sonrasında klinik görünüm ve tomografik incelemede bulguların ge­rilediği saptandı.

References

  • Bairey O, Kremer I, Rakowsky E, Hadar H, Shaklai M.Orbital and adnexal involvement in systemic Non-Hodgkin’s lym- phoma. Cancer 1994;73:2395-2399.
  • Barışta İ, Güllü İ, Akpek B, Demirkazık F, Ayhan A, Baltalı E, Tekuzman G, Fırat D: Non-Hodgkin lenfomalarda oküler ve orbital tutulum. T Oft Gaz 1994;24:392-395.
  • Liang R, Loke SL, Chiu E.A clinico-pathological cases of Non-Hodgkin lymphoma involving in orbit. Acta Oncol 1991;30:335-338.
  • Jenkins C, Rose GE, Bunce C, Cree I, Norton A, Plowman PN, Moseley I, Wright JE. Clinical features associated with survival of patients with lymphoma of the ocular adnexa. Eye 2003;17:809-820.
  • Crawford JB. Conjunctival tumours. In: Tasman W, Jaeger EA, eds. Duane’s clinical ophthalmology, Vol. 4. Philadel- phia: JB Lippincott, 1994;10:2-10:6.
  • Klapper SR, Jordan DR, McLeish W, Pelletier C. Unilateral proptosis in an immunocompetant man as the initial clinical manifestation of systemic Hodgkin disease. Ophthalmol- ogy 1999;106:338-341.
  • Rosenburg PA, Kaplan HS. Evidence for an orderly pro- gression in the spread of Hodgkin’s disease. Cancer Res 1996;26:1225-31.
  • Fitzpatrick PJ, Macko S. Lymphoreticular tumours of the or- bit. Int J Radiation Oncol Biol Phys 1984;10:333-340.
  • Vaughan GJ, Dortzbach RK. Eyelid malignancies. In: Yanoff M, Duker JS. Ophthalmology. Mosby. 1999;7:12-16.
  • Tiwari RM. Lymphosarcoma of lacrimal gland. Laryngo- scope 1971;81:1519-1523.
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Case Reports
Authors

Özlem Yalçın Tök This is me

Levent Tök This is me

Fatma Akbaş Kocaoğlu This is me

Züleyha Yalnız This is me

Firdevs Örnek Örnek This is me

Publication Date March 1, 2010
Submission Date March 2, 2015
Published in Issue Year 2010 Volume: 37 Issue: 1

Cite

APA Tök, Ö. Y., Tök, L., Kocaoğlu, F. A., Yalnız, Z., et al. (2010). Sistemik Hodgkin hastalığında iki taraflı lakrimal bez tutulumu. Dicle Tıp Dergisi, 37(1), 67-70.
AMA Tök ÖY, Tök L, Kocaoğlu FA, Yalnız Z, Örnek FÖ. Sistemik Hodgkin hastalığında iki taraflı lakrimal bez tutulumu. diclemedj. March 2010;37(1):67-70.
Chicago Tök, Özlem Yalçın, Levent Tök, Fatma Akbaş Kocaoğlu, Züleyha Yalnız, and Firdevs Örnek Örnek. “Sistemik Hodgkin hastalığında Iki Taraflı Lakrimal Bez Tutulumu”. Dicle Tıp Dergisi 37, no. 1 (March 2010): 67-70.
EndNote Tök ÖY, Tök L, Kocaoğlu FA, Yalnız Z, Örnek FÖ (March 1, 2010) Sistemik Hodgkin hastalığında iki taraflı lakrimal bez tutulumu. Dicle Tıp Dergisi 37 1 67–70.
IEEE Ö. Y. Tök, L. Tök, F. A. Kocaoğlu, Z. Yalnız, and F. Ö. Örnek, “Sistemik Hodgkin hastalığında iki taraflı lakrimal bez tutulumu”, diclemedj, vol. 37, no. 1, pp. 67–70, 2010.
ISNAD Tök, Özlem Yalçın et al. “Sistemik Hodgkin hastalığında Iki Taraflı Lakrimal Bez Tutulumu”. Dicle Tıp Dergisi 37/1 (March 2010), 67-70.
JAMA Tök ÖY, Tök L, Kocaoğlu FA, Yalnız Z, Örnek FÖ. Sistemik Hodgkin hastalığında iki taraflı lakrimal bez tutulumu. diclemedj. 2010;37:67–70.
MLA Tök, Özlem Yalçın et al. “Sistemik Hodgkin hastalığında Iki Taraflı Lakrimal Bez Tutulumu”. Dicle Tıp Dergisi, vol. 37, no. 1, 2010, pp. 67-70.
Vancouver Tök ÖY, Tök L, Kocaoğlu FA, Yalnız Z, Örnek FÖ. Sistemik Hodgkin hastalığında iki taraflı lakrimal bez tutulumu. diclemedj. 2010;37(1):67-70.