Quality of life in adult patients with acne vulgaris before and after treatment

Year 2011, Volume: 38 Issue: 3, 282 - 288, 01.09.2011

Hikmet Akyazı Davut Baltacı Köksal Alpay Çiçek Hocaoğlu

https://doi.org/10.5798/diclemedj.0921.2011.03.0032

Cited By: 3

Abstract

Objectives: To investigate effect of acne treatment on quality of life in patients with acne vulgaris. Materials and methods: The study was prospective and conducted in a university hospital, enrolling the previously untreated patients with acne vulgaris. Before treatment, dermatology life quality index (DLQI) was applied to all participants of both study and control group. After 3rd and 6th months of treatment administration, DLQI tool was applied to patients in the study group, and scores were compared. Results: The acne severity of patients in the study group was 17 (27.9%), 34 (55.7%) and 10 (16.4%) for mild, moderate and severe form, respectively. Mean scoring for DLQI in the study group and the control group was 8.74±5.07 and 2.21±2.44, respectively (p=0.0005). In the study, significant difference were observed in life qual­ity scores between severe acne and mild acne patients, and between severe acne and moderate acne patients (p=0.003 and p=0.011, respectively), but not between mild and moderate acne patients (p=0.937). Effect of gen­der in acne vulgaris on quality of life was not significantly different (p=0.336). At stage of treatment at the end of 3rd and 6th month, improvements on quality of life was ob­served significant for overall and all classification of acne severity (mild, moderate and severe; p

Keywords

Skin disease, acne treatment, dermatologi­cal life quality index

Erişkin akne vulgaris hastalarında tedavi öncesi ve sonrası hayat kalitesi

Abstract

Amaç: Akne vulgaris hastalarında akne tedavisinin hayat kalitesi üzerine etkisinin incelenmesi amaçlanmıştır. Gereç ve yöntem: Çalışma prospektif olarak tasarlandı. Daha öncesinde akne tedavisi almayan hastalar alındı ve çalışma bir üniversite hastanesinde yürütüldü. Çalışma grubu ve kontrol grubu oluşturuldu. Tedavi öncesi hastala­ra ve kontrol grubuna Dermatolojik Yaşam Kalitesi İndeksi (DYKI) ölçeği uygulandı. Tedavi sonrası 3. ve 6. aylarda DYKI tekrar uygulandı. Tüm Skorlar karşılaştırıldı. Bulgular: Çalışma grubunda bulunan akne olguların­dan 17 (%27,9) hasta hafif, 34 hasta orta (%55,7) ve 10 hasta (%16,4) ileri derece akne grubunda idi. Çalışma grubu ve kontrol grubunun ortalama DYKI skoru sırası ile 8,74±5,07 ve 2,21±2,44 idi (p=0,0005). Çalışma gru­bunda ileri derece akne ile orta derece akne; ileri derece akne ile hafif dereceli akne arasında yaşam kalitesi skoru arasında anlamlı fark izlendi (p=0,003, p=0,011 sırası ile), fakat hafif ve orta derece akne arasında fark izlenmedi (p=0,036). Cinsiyetin akne vulgarisin hastalarında yaşam kalitesi üzerine etkisi izlenmedi (p=0,336). Tedavinin 3. ve 6. aylarında çalışma grubunda yaşam kalitesi tüm olgu ve her bir akne derecesi (hafif, orta ve ileri derece) için tekrar değerlendirildi (sırası ile; p

Keywords

Deri hastalığı, akne tedavisi, derma­tolojik yaşam kalitesi indeksi

References

• Cook D, Krassas G, Huang T. Acne - best practice manage- ment. Aust Fam Physician 2010; 39(9):656-60.
• Sinclair W, Jordaan HF; Global Alliance to Improve Out- comes in Acne. Acne guideline 2005 update. S Afr Med J 2005; 95(11):881-92.
• Do JE, Cho SM, In SI, Lim KY, Lee S, Lee ES. Psychosocial Aspects of Acne Vulgaris: A Community-based Study with Korean Adolescents. Ann Dermatol 2009; 21(2):125-129.
• Tan JK. Psychosocial impact of acne vulgaris: evaluating the evidence. Skin Therapy Lett 2004; 9(7):1-3.
• Grahame V, Dick DC, Morton CM, Watkins O, Power KG. The psychological correlates of treatment efficacy in acne. Dermatol Psychosom 2002; 3(3):119-25.
• Ozturkcan S, Aydemir O, Inanır I. Akne vulgarisli hastalarda yaşam kalitesi. T Klin Dermatol 2002; 12(3):131-4.
• Martin AR, Lookingbill DP, Botek A, Light J, Thiboutot D, Girman CJ. Health-related quality of life among patients with facial acne -- assessment of a new acne-specific ques- tionnaire. Clin Exp Dermatol 2001; 26(5):380-5.
• Rapp DA, Brenes GA, Feldman SR, Fleischer AB Jr, Graham GF, Dailey M, Rapp SR. Anger and acne: implications for quality of life, patient satisfaction and clinical care. Br J Dermatol 2004; 151(1):183-9.
• Lehmann HP, Andrews JS, Robinson KA, Holloway VL, Goodman SN. Management of acne. Evid Rep Technol As- sess 2001;21(17):1-3.
• Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI) - a simple practical measure for routine clinical use. Clin Exp Dermatol Clin Exp 1994; 19(3):210-6.
• Ozturkcan S, Ermertcan AT, Eser E, Sahin MT. Cross vali- dation of the Turkish version of dermatology life quality index. Int J Dermatol 2006; 45(11):1300-7.
• Gurel MS, Yanik M, Simsek Z, Kati M, Karaman A. Quality of life instrument for Turkish people with skin diseases. Int J Dermatol 2005; 44(11):933-8.
• Cuhadaroglu F, Yazici KM. Psychiatric symptoms among Turkish adolescents. Turk J Pediatr 1999; 41(3):307-13.
• Davis EC, Callender VD. A review of acne in ethnic skin: pathogenesis, clinical manifestations, and management strategies. J Clin Aesthet Dermatol 2010; 3(4):24-8.
• Acıoz E, Gokdemir G, Köşlü A; Dermatolojide Yaşam Kali- tesi. Turkderm 2003; 37(1):16-23.
• Hensen G, Schiller M, Luger TA, Hensen P. Psychological issues in outpatient care of acne vulgaris. Gesundheitswes- en 2009;71(7):405-13.
• Lasek RJ, Chren MM. Acne vulgaris and the quality of life of adult dermatology patients. Arch Dermatol 1998; 134(4):454-8.
• Thomas DR. Psychosocial effects of acne. J Cutan Med Surg 2004; 8(4):3-5.
• Rubinov DR, Peck GL, Squillace KM, Gantt GG. Reduced anxiety and depression in cystic acne patients after success- ful treatment with oral isotretinoin. J Am Acad Dermatol 1987; 17(1):25-32.
• Yazici K, Baz K, Yazici AE, Kokturk A, Tot S, Demirseren D, Buturak V. Disease-specific quality of life is associated with anxiety and depression in patients with acne. J Eur Acad Dermatol Venereol 2004; 18(4):435-9.
• Smithard A. Glazebrook C. Williams HC. Acne prevalence, knowledge about acne and psychological morbidity in mid-adolescence: a community-based study. Br J Dermatol 2001; 145 (2):274-9.
• Fehnel SE, McLeod LD, Brandman J, et al. Responsiveness of the Acne-Specific Quality of Life Questionnaire (Acne- QoL) to treatment for acne vulgaris in placebo-controlled clinical trials. Qual Life Res 2002; 11(8):809-16.
• Kellett SC, Gawkrodger DJ. The psychological and emo- tional impact of acne and the effect of treatment with isot- retinoin. Br J Dermatol 1999; 140 (2):273-82.