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Evaluation of the relationship between coronary artery calcium score and coronary artery disease by multislice computed tomography

Year 2013, Volume: 40 Issue: 4, 632 - 636, 01.12.2013
https://doi.org/10.5798/diclemedj.0921.2013.04.0346

Abstract

Objective: Coronary artery disease (CAD) is the major cause of deaths in developed countries and early diagnosis and treatment can reduce the mortality and morbidity. In this study, we aimed to investigate the multislice computed tomography (MSCT) evaluation the relationship between well-established risk factors, angiographic features and coronary artery calcium-scores. Methods: Coronary artery calcium-scores and angiography features of 141 CAD patients achieved by MSCT were evaluated retrospectively. Classical coronary risk factors of patients including hyperlipidemia, hypertension, diabetes, family history of CAD and history of smoking were recorded. Calcium-score of patients based on the classification of Agatston was calculated. Results: The mean age of 141 patients was 56±12 years (Range, 17-80). In 33 patients (23%), the percentages of coronary artery stenosis detected by MDCT were over 50%. Diabetes mellitus and hypertension were the sole coronary risk factors that had statistically significant correlation (p=0,023 and p

References

  • Ridker PM, Genest J, Libby P. Risk factors for atheroscle- rotic disease. In: Braunwald E, Zipes DP, Lippy P (eds): Heart Disease, 6th ed. WB Saunders 2001;1010.
  • Falk E, Shah PK, Fuster V. Coronary plaque distruption. Cir- culation 1995;92:657-671.
  • Wexler L, Brundage B, Crouse J, et al. Coronary artery cal- cification: pathophysiology, epidemiyology, imaging meth- ods, and clinical implications. A statement for health pro- fessionals from the American Heart Association. Writing group. Circulation 1996;94:1175-1192.
  • Janowitz WR, Agatston AS, Viamonte M Jr. Comparison of serial quantitative evaluation of calcified coronary artery plaque by ultrafast computed tomography in persons with and without obstructive coronary artery disease. Am J Car- diol 1991;68:1-6.
  • Agatston AS, Janowitz WR, Hildner FJ, et al. Quantification of coronary artery calcium using ultrafast computed tomog- raphy. J Am Coll Cardiol 1990;15:827-832.
  • Breen JF, Sheedy PF II, Schwartz RS, et al. Coronary artery calcification detected with ultrafast CT as an indication of coronary artery disease. Radiology 1992;185:435-439.
  • Carrascosa PM, Capunay CM, Merletti PG. Negative cal- cium scoring: Can it rule out severe stenosis? ECR-EPOS. 2004; March 5-9, Vienna, Austria.
  • Greenland P, LaBree L, Azen SP, et al. Coronary artery cal- cium score combined with Framingham Score for risk pre- diction in asymptomatic individuals. JAMA 2004;291:210- 215.
  • Shaw LJ, Raggl P, Schisterman E, et al. Prognostic value of cardiac risk factors and coronary artery calcium screening for all-cause mortality. Radiology 2003;228:826-833.
  • Rumberger JA, Sheedy PF, Breen JF, Schwartz RS. Elec- tron beam computed tomographic coronary calcium score cutpoints and severity of associated angiographic lumen stenosis. J Am Coll Cardiol 1997;29:1542-1548.
  • Schurgin S, Rich S, Mazzone T. Increased prevalence of significant coronary artery calcification in patients with Diabetes. Diabetes Care 2001;24:335-338.
  • Megnien JL, Simon A, Lenariey M, et al. Hypertension pro- motes coronary calcium deposit in asymptomatic men. Am Heart Assoc 1996;27:949-954.
  • Wong ND, Kawakubo M, LaBree L, et al. Relation of coro- nary calcium progression and control of lipids according to national cholesterol education program guidelines. Am J Cardiol 2004;94:431-436.
  • Shaw LJ, Raggi P, Callister TQ, Berman DS. Prognostic value of coronary artery calcium screening in asymptomat- ic smokers and non-smokers. Eur Heart J 2006;27:968-975.

Koroner arter kalsiyum skoru ile koroner arter hastalığı arasındaki ilişkinin çok kesitli bilgisayarlı tomografi ile değerlendirilmesi

Year 2013, Volume: 40 Issue: 4, 632 - 636, 01.12.2013
https://doi.org/10.5798/diclemedj.0921.2013.04.0346

Abstract

Amaç: Koroner arter hastalığı (KAH) gelişmiş ülkelerde en sık ölüm nedeni olup, erken tanı ve tedavisi mortalite ve morbidite oranlarını azaltmada büyük önem taşımaktadır. Biz bu çalışmada multidetektör bilgisayarlı tomografi (MDBT) tetkiki ile KAH olgularındaki klasik risk faktörleri, anjiografi bulguları ve koroner arter kalsiyum skoru arasındaki ilişkinin değerlendirilmesini amaçladık. Yöntemler: Çalışmamızda 141 koroner arter hastasına ait MDBT ile elde edilmiş koroner arter kalsiyum skorları ve anjiografi bulguları retrospektif olarak değerlendirildi. Hastalarda hiperlipidemi, hipertansiyon, diyabet, ailesel koroner arter hastalığı ve sigara kullanma öyküsü gibi klasik koroner risk faktörlerinin varlığı kaydedildi. Hastaların kalsiyum skoru Agatston sınıflamasına göre hesaplandı. Bulgular: Çalışmaya alınan 141 hastanın ortalama yaş 56±12 olup yaş aralığı 17 ile 80 arasında değişmekteydi. Otuz üç (%23) hastada MDBT ile saptanan koroner arter darlık yüzdeleri %50\'nin üzerinde idi. Diyabet ve hipertansiyon; koroner kalsiyum skoru ile istatistiksel olarak anlamlı korelasyon gösteren (sırasıyla p=0,023 ve p

References

  • Ridker PM, Genest J, Libby P. Risk factors for atheroscle- rotic disease. In: Braunwald E, Zipes DP, Lippy P (eds): Heart Disease, 6th ed. WB Saunders 2001;1010.
  • Falk E, Shah PK, Fuster V. Coronary plaque distruption. Cir- culation 1995;92:657-671.
  • Wexler L, Brundage B, Crouse J, et al. Coronary artery cal- cification: pathophysiology, epidemiyology, imaging meth- ods, and clinical implications. A statement for health pro- fessionals from the American Heart Association. Writing group. Circulation 1996;94:1175-1192.
  • Janowitz WR, Agatston AS, Viamonte M Jr. Comparison of serial quantitative evaluation of calcified coronary artery plaque by ultrafast computed tomography in persons with and without obstructive coronary artery disease. Am J Car- diol 1991;68:1-6.
  • Agatston AS, Janowitz WR, Hildner FJ, et al. Quantification of coronary artery calcium using ultrafast computed tomog- raphy. J Am Coll Cardiol 1990;15:827-832.
  • Breen JF, Sheedy PF II, Schwartz RS, et al. Coronary artery calcification detected with ultrafast CT as an indication of coronary artery disease. Radiology 1992;185:435-439.
  • Carrascosa PM, Capunay CM, Merletti PG. Negative cal- cium scoring: Can it rule out severe stenosis? ECR-EPOS. 2004; March 5-9, Vienna, Austria.
  • Greenland P, LaBree L, Azen SP, et al. Coronary artery cal- cium score combined with Framingham Score for risk pre- diction in asymptomatic individuals. JAMA 2004;291:210- 215.
  • Shaw LJ, Raggl P, Schisterman E, et al. Prognostic value of cardiac risk factors and coronary artery calcium screening for all-cause mortality. Radiology 2003;228:826-833.
  • Rumberger JA, Sheedy PF, Breen JF, Schwartz RS. Elec- tron beam computed tomographic coronary calcium score cutpoints and severity of associated angiographic lumen stenosis. J Am Coll Cardiol 1997;29:1542-1548.
  • Schurgin S, Rich S, Mazzone T. Increased prevalence of significant coronary artery calcification in patients with Diabetes. Diabetes Care 2001;24:335-338.
  • Megnien JL, Simon A, Lenariey M, et al. Hypertension pro- motes coronary calcium deposit in asymptomatic men. Am Heart Assoc 1996;27:949-954.
  • Wong ND, Kawakubo M, LaBree L, et al. Relation of coro- nary calcium progression and control of lipids according to national cholesterol education program guidelines. Am J Cardiol 2004;94:431-436.
  • Shaw LJ, Raggi P, Callister TQ, Berman DS. Prognostic value of coronary artery calcium screening in asymptomat- ic smokers and non-smokers. Eur Heart J 2006;27:968-975.
There are 14 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Tuba Kartal This is me

Alpaslan Yavuz This is me

Mehmet Güli Çetinçakmak This is me

Cemil Göya This is me

Metin Çubuk This is me

Publication Date December 1, 2013
Submission Date March 2, 2015
Published in Issue Year 2013 Volume: 40 Issue: 4

Cite

APA Kartal, T., Yavuz, A., Çetinçakmak, M. G., Göya, C., et al. (2013). Koroner arter kalsiyum skoru ile koroner arter hastalığı arasındaki ilişkinin çok kesitli bilgisayarlı tomografi ile değerlendirilmesi. Dicle Tıp Dergisi, 40(4), 632-636. https://doi.org/10.5798/diclemedj.0921.2013.04.0346
AMA Kartal T, Yavuz A, Çetinçakmak MG, Göya C, Çubuk M. Koroner arter kalsiyum skoru ile koroner arter hastalığı arasındaki ilişkinin çok kesitli bilgisayarlı tomografi ile değerlendirilmesi. diclemedj. December 2013;40(4):632-636. doi:10.5798/diclemedj.0921.2013.04.0346
Chicago Kartal, Tuba, Alpaslan Yavuz, Mehmet Güli Çetinçakmak, Cemil Göya, and Metin Çubuk. “Koroner Arter Kalsiyum Skoru Ile Koroner Arter hastalığı arasındaki ilişkinin çok Kesitli Bilgisayarlı Tomografi Ile değerlendirilmesi”. Dicle Tıp Dergisi 40, no. 4 (December 2013): 632-36. https://doi.org/10.5798/diclemedj.0921.2013.04.0346.
EndNote Kartal T, Yavuz A, Çetinçakmak MG, Göya C, Çubuk M (December 1, 2013) Koroner arter kalsiyum skoru ile koroner arter hastalığı arasındaki ilişkinin çok kesitli bilgisayarlı tomografi ile değerlendirilmesi. Dicle Tıp Dergisi 40 4 632–636.
IEEE T. Kartal, A. Yavuz, M. G. Çetinçakmak, C. Göya, and M. Çubuk, “Koroner arter kalsiyum skoru ile koroner arter hastalığı arasındaki ilişkinin çok kesitli bilgisayarlı tomografi ile değerlendirilmesi”, diclemedj, vol. 40, no. 4, pp. 632–636, 2013, doi: 10.5798/diclemedj.0921.2013.04.0346.
ISNAD Kartal, Tuba et al. “Koroner Arter Kalsiyum Skoru Ile Koroner Arter hastalığı arasındaki ilişkinin çok Kesitli Bilgisayarlı Tomografi Ile değerlendirilmesi”. Dicle Tıp Dergisi 40/4 (December 2013), 632-636. https://doi.org/10.5798/diclemedj.0921.2013.04.0346.
JAMA Kartal T, Yavuz A, Çetinçakmak MG, Göya C, Çubuk M. Koroner arter kalsiyum skoru ile koroner arter hastalığı arasındaki ilişkinin çok kesitli bilgisayarlı tomografi ile değerlendirilmesi. diclemedj. 2013;40:632–636.
MLA Kartal, Tuba et al. “Koroner Arter Kalsiyum Skoru Ile Koroner Arter hastalığı arasındaki ilişkinin çok Kesitli Bilgisayarlı Tomografi Ile değerlendirilmesi”. Dicle Tıp Dergisi, vol. 40, no. 4, 2013, pp. 632-6, doi:10.5798/diclemedj.0921.2013.04.0346.
Vancouver Kartal T, Yavuz A, Çetinçakmak MG, Göya C, Çubuk M. Koroner arter kalsiyum skoru ile koroner arter hastalığı arasındaki ilişkinin çok kesitli bilgisayarlı tomografi ile değerlendirilmesi. diclemedj. 2013;40(4):632-6.