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Osseous Metaplasia in mitral valve in an elderly case

Year 2013, Volume: 40 Issue: 3, 487 - 489, 01.09.2013
https://doi.org/10.5798/diclemedj.0921.2013.03.0316

Abstract

Metaplasia is a reversible replacement of one cell type with another mature differentiated cell type. Osseous metaplasia refers to the formation of mature bone elements in extraskeletal tissues. It can occur anywhere in body. It is encountered very rarely. This rare finding has been reported in some tissues and neoplasia of various organs. Osseous metaplasia in cardiac valves appears infrequently in literature. The exact pathophysiologic mechanisms of osseous metaplasia and the origin of bone cells in ossified valves are unknown. However, this metaplasia process has been reported to be closely related with calcification .In our study we aimed to present a case in which we diagnosed as osseous metaplasia in mitral valve.

References

  • Kumar V, Cotran RS, Robbins SL. Robbins Basic Pathology. 7. Baskı. Nobel Tıp Kitabevi.2003:14.
  • Cayuela E, Perez-Medina T, Vilanova J, et al. True osseous metaplasia of the endometrium: The bone is not from a fe- tus. Fertil Steril 2009;91:1293.
  • Steiner I, Kasparová P, Kohout A, Dominik J. Bone forma- tion in cardiac valves: a histopathological study of 128 cases. Virchows Arch 2007;450:653-657.
  • Gal-Gombos EC, Esserman LE, Poniecka AW, et al. Poppiti RJ. Osseous metaplasia of the breast: diagnosis with stereo- tactic core biopsy. Breast J 2002;8:50-52.
  • Murugan P, Basu D, Manikandan R, et al. Osseous metapla- sia in renal cell carcinoma: report of a rare case. Indian J Pathol Microbiol 2008;51:399-401.
  • Ardito G, Fadda G, Revelli L, et al. Follicular adenoma of the thyroid gland with extensive bone metaplasia. J Exp Clin Cancer Res 2001;20:443-445.
  • Agnihotri S, Sarma NH, Jeebun N, Srivastava R. Osseous metaplasia in adenocarcinoma of the rectum: A case report. The Internet Journal of Gastroenterology 2008;7:23.
  • Mirzaie M, Schultz M, Schwartz P, et al. Evidence of woven bone formation in heart valve disease. Ann Thorac Cardio- vasc Surg 2003;9:163-169.
  • Mohler ER, Gannon F, Reynolds C, et al. Bone formation and inflammation in cardiac valves. Circulation 2001;103:1522- 1528.
  • Mohler ER, Chawla MK, Chang AW, et al. Gannon FH. Identification and characterization of calcifying valve cells from human and canine aortic valves. J Heart Valve Dis 1999;8:254-260.

İleri yaş bir olguda mitral kapakta osseöz metaplazi

Year 2013, Volume: 40 Issue: 3, 487 - 489, 01.09.2013
https://doi.org/10.5798/diclemedj.0921.2013.03.0316

Abstract

Metaplazi, bir hücre tipinin bir başka matür diferansiye hücre tipi ile reversibl yer değiştirmesidir. Osseöz metaplazi iskelet dışı dokularda olgun kemik elemanlarının oluşumu anlamına gelir. Vücutta her yerde oluşabilir. Çok nadir rastlanır. Bu nadir bulgu bazı dokularda ve çeşitli organların neoplazilerinde rapor edilmiştir. Literatürde kalp kapaklarında osseöz metaplazi nadiren görülmektedir. Osseöz metaplazinin tam patofizyolojik mekanizması ve ossifiye kapaklardaki kemik hücrelerinin kaynağı bilinmemektedir. Ancak bu metaplazi sürecinin kalsifikasyonla yakından ilişkili olduğu bildirilmektedir. Çalışmamızda mitral kapakta osseöz metaplazi tanısı koyduğumuz olgumuzu sunmayı amaçladık.

References

  • Kumar V, Cotran RS, Robbins SL. Robbins Basic Pathology. 7. Baskı. Nobel Tıp Kitabevi.2003:14.
  • Cayuela E, Perez-Medina T, Vilanova J, et al. True osseous metaplasia of the endometrium: The bone is not from a fe- tus. Fertil Steril 2009;91:1293.
  • Steiner I, Kasparová P, Kohout A, Dominik J. Bone forma- tion in cardiac valves: a histopathological study of 128 cases. Virchows Arch 2007;450:653-657.
  • Gal-Gombos EC, Esserman LE, Poniecka AW, et al. Poppiti RJ. Osseous metaplasia of the breast: diagnosis with stereo- tactic core biopsy. Breast J 2002;8:50-52.
  • Murugan P, Basu D, Manikandan R, et al. Osseous metapla- sia in renal cell carcinoma: report of a rare case. Indian J Pathol Microbiol 2008;51:399-401.
  • Ardito G, Fadda G, Revelli L, et al. Follicular adenoma of the thyroid gland with extensive bone metaplasia. J Exp Clin Cancer Res 2001;20:443-445.
  • Agnihotri S, Sarma NH, Jeebun N, Srivastava R. Osseous metaplasia in adenocarcinoma of the rectum: A case report. The Internet Journal of Gastroenterology 2008;7:23.
  • Mirzaie M, Schultz M, Schwartz P, et al. Evidence of woven bone formation in heart valve disease. Ann Thorac Cardio- vasc Surg 2003;9:163-169.
  • Mohler ER, Gannon F, Reynolds C, et al. Bone formation and inflammation in cardiac valves. Circulation 2001;103:1522- 1528.
  • Mohler ER, Chawla MK, Chang AW, et al. Gannon FH. Identification and characterization of calcifying valve cells from human and canine aortic valves. J Heart Valve Dis 1999;8:254-260.
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Case Reports
Authors

Sezen Koçarslan This is me

Aydemir Koçarslan This is me

Muhammet Emin Güldür This is me

Emine Zeynep Tarini This is me

Hasan İlyas Özardalı This is me

Publication Date September 1, 2013
Submission Date March 2, 2015
Published in Issue Year 2013 Volume: 40 Issue: 3

Cite

APA Koçarslan, S., Koçarslan, A., Güldür, M. E., Tarini, E. Z., et al. (2013). İleri yaş bir olguda mitral kapakta osseöz metaplazi. Dicle Medical Journal, 40(3), 487-489. https://doi.org/10.5798/diclemedj.0921.2013.03.0316
AMA Koçarslan S, Koçarslan A, Güldür ME, Tarini EZ, Özardalı Hİ. İleri yaş bir olguda mitral kapakta osseöz metaplazi. diclemedj. September 2013;40(3):487-489. doi:10.5798/diclemedj.0921.2013.03.0316
Chicago Koçarslan, Sezen, Aydemir Koçarslan, Muhammet Emin Güldür, Emine Zeynep Tarini, and Hasan İlyas Özardalı. “İleri Yaş Bir Olguda Mitral Kapakta osseöz Metaplazi”. Dicle Medical Journal 40, no. 3 (September 2013): 487-89. https://doi.org/10.5798/diclemedj.0921.2013.03.0316.
EndNote Koçarslan S, Koçarslan A, Güldür ME, Tarini EZ, Özardalı Hİ (September 1, 2013) İleri yaş bir olguda mitral kapakta osseöz metaplazi. Dicle Medical Journal 40 3 487–489.
IEEE S. Koçarslan, A. Koçarslan, M. E. Güldür, E. Z. Tarini, and H. İ. Özardalı, “İleri yaş bir olguda mitral kapakta osseöz metaplazi”, diclemedj, vol. 40, no. 3, pp. 487–489, 2013, doi: 10.5798/diclemedj.0921.2013.03.0316.
ISNAD Koçarslan, Sezen et al. “İleri Yaş Bir Olguda Mitral Kapakta osseöz Metaplazi”. Dicle Medical Journal 40/3 (September 2013), 487-489. https://doi.org/10.5798/diclemedj.0921.2013.03.0316.
JAMA Koçarslan S, Koçarslan A, Güldür ME, Tarini EZ, Özardalı Hİ. İleri yaş bir olguda mitral kapakta osseöz metaplazi. diclemedj. 2013;40:487–489.
MLA Koçarslan, Sezen et al. “İleri Yaş Bir Olguda Mitral Kapakta osseöz Metaplazi”. Dicle Medical Journal, vol. 40, no. 3, 2013, pp. 487-9, doi:10.5798/diclemedj.0921.2013.03.0316.
Vancouver Koçarslan S, Koçarslan A, Güldür ME, Tarini EZ, Özardalı Hİ. İleri yaş bir olguda mitral kapakta osseöz metaplazi. diclemedj. 2013;40(3):487-9.