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Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends

Year 2025, Volume: 52 Issue: 3, 569 - 576, 16.09.2025
https://doi.org/10.5798/dicletip.1785132

Abstract

Background: Allergic diseases are increasingly prevalent in children, leading to frequent pediatric inpatient consultations for allergy. However, detailed data on the clinical indications for such referrals in hospitalized children remain limited. This study aimed to analyze consultation patterns, diagnoses, and outcomes in pediatric allergy referrals over one year at a tertiary care center.
Methods: We retrospectively reviewed 992 allergy consultations conducted 795 pediatric inpatients at Ankara Bilkent City Hospital between April 2023 and April 2024. Patient demographics, clinical presentations, diagnostic evaluations, treatment approaches, and consultation outcomes were analyzed.
Results: A total of 992 allergy consultations were conducted for 795 pediatric inpatients, with 60.0% (n=477) being male. The most common age group was 0–2 years (28.3%). Respiratory tract symptoms were the leading reason for consultation (50.8%), with asthma or suspected asthma diagnosed in 57.3% of these patients. Among those with wheezing infant, the diagnosis was confirmed in 58.6%. Suspected drug allergy was the second most common indication (26.0%), primarily presenting as maculopapular rash (n=107) or urticaria (n=80), with 12 cases evaluated for severe cutaneous adverse reactions. Anaphylaxis was identified in 31 patients, mostly triggered by drugs (n=19), followed by foods (n=11). Less common indications included food allergy (7.8%), atopic dermatitis (3.1%), transfusion reactions (1.6%), and eosinophilia (1.4%).
Conclusion: Pediatric allergy consultations in this tertiary center predominantly address respiratory symptoms and drug hypersensitivity. Specialist evaluation facilitates accurate diagnosis, safe drug administration, and appropriate management, highlighting the crucial role of inpatient allergy services. These consultations also provide significant educational value for pediatric residents, underscoring the importance of integrated allergy involvement in inpatient pediatric care.

Ethical Statement

The study was approved by the Institutional Ethics Committee of Ankara Bilkent City Hospital (approval number: TABED1-24-550)

References

  • 1.Zablotsky B, Black LI, Akinbami LJ. Diagnosedallergic conditions in children aged 0–17 years:United States, 2021. Natl Health Stat Report.2023;(459):1-8.
  • 2.Özmen S, Mısırlıoğlu ED, Giniş T, et al.Consultations in pediatric allergy. Turk J Pediatr Dis. 2011;5(4):202-7.
  • 3.Wurst M, Brameli A, Krantz M, et al. Evolvingpatterns in inpatient pediatric consultations toallergy/immunology at an academic medical center.Int J Med Stud. 2024;12(3):278-83..
  • 4.Zuberbier T, Aberer W, Asero R, et al. TheEAACI/GA²LEN/EDF/WAO guideline for thedefinition, classification, diagnosis and management of urticaria. Allergy. 2018;73(7):1393-414.
  • 5.Cardona V, Ansotegui IJ, Ebisawa M, et al. WorldAllergy Organization anaphylaxis guidance 2020.World Allergy Organ J. 2020;13(10):100472.
  • 6.Brockow K, Ardern-Jones MR, Mockenhaupt M, etal. EAACI position paper on how to classifycutaneous manifestations of drug hypersensitivity.Allergy. 2019;74(1):14-27.
  • 7.Broyles AD, Banerji A, Castells M. Practicalguidance for the evaluation and management ofdrug hypersensitivity: general concepts. J AllergyClin Immunol Pract. 2020;8(9 Suppl):3-15.
  • 8.Castells M. Rapid desensitization forhypersensitivity reactions to medications. ImmunolAllergy Clin North Am. 2009;29(3):585-606.
  • 9.Muraro A, Halken S, Arshad S, et al. EAACI foodallergy and anaphylaxis guidelines. Allergy.2014;69(5):590-601.
  • 10.England RW, Ho TC, Napoli DC, Quinn JM.Inpatient consultation of allergy/immunology in atertiary care setting. Ann Allergy Asthma Immunol.2003;90(4):393-7.
  • 11.Otto HF, England RW, Quinn JM, editors.Inpatient allergy/immunology consultations in atertiary care setting. Allergy Asthma Proc.2010;31(2):165-71.
  • 12.Dietrich JJ, Quinn JM, England RW, editors.Reasons for outpatient consultation inallergy/immunology. Allergy Asthma Proc.2009;30(4):397-401.
  • 13.Quinn JM. Pediatric inpatient consultation ofallergy/immunology. Pediatr Asthma AllergyImmunol. 2000;14(4):293-9.

Yatarak Tedavi Gören Pediatrik Hastalarda Alerji Konsültasyonları: Bir Yıllık Değerlendirme

Year 2025, Volume: 52 Issue: 3, 569 - 576, 16.09.2025
https://doi.org/10.5798/dicletip.1785132

Abstract

Giriş: Alerjik hastalıkların çocuklarda giderek artan sıklığı, çocuk hastalarda alerji kliniğine yapılan yatan hasta konsültasyonlarını yaygınlaştırmaktadır. Ancak hastanede yatan çocuklara yapılan bu konsültasyonların klinik nedenlerine ilişkin ayrıntılı veriler literatürde sınırlıdır. Bu çalışma, üçüncü basamak bir merkezde bir yıl boyunca yapılan çocuk alerji konsültasyonlarının nedenlerini, tanılarını ve sonuçlarını analiz etmeyi amaçlamaktadır.
Yöntemler: Nisan 2023 ile Nisan 2024 tarihleri arasında Ankara Bilkent Şehir Hastanesi’nde yatan 795 pediatrik hastaya yapılan toplam 992 alerji konsültasyonu retrospektif olarak incelendi. Hastaların demografik özellikleri, klinik başvuru nedenleri, tanısal değerlendirmeleri, tedavi yaklaşımları ve konsültasyon sonuçları analiz edildi.
Bulgular: Toplam 795 pediatrik hasta için 992 alerji konsültasyonu gerçekleştirildi; hastaların %60,0’ı (n=477) erkekti. En sık görülen yaş grubu %28,3 (n=225) ile 0–2 yaş aralığıydı. Konsültasyonların en yaygın nedeni %50,8 (n=405) ile solunum yolu semptomlarıydı; bu hastaların %57,3’üne astım veya astım ön tanısı konuldu. Hışıltılı çocuk olduğu düşünülen olguların %58,6’sında tanı doğrulandı. İkinci en sık konsültasyon nedeni %26,0 (n=208) ile ilaç alerjisiydi ve bu durum en çok makülopapüler döküntü (n=107) ve ürtiker (n=80) şeklinde seyretti; ayrıca 12 hasta ciddi kutanöz advers reaksiyonlar açısından değerlendirildi. Anafilaksi 31 hastada saptandı ve çoğunlukla ilaçlarla (n=19), daha az sıklıkla besinlerle (n=11) ilişkiliydi. Daha nadir nedenler arasında besin alerjisi (%7,8), atopik dermatit (%3,1), transfüzyon reaksiyonları (%1,6) ve eozinofili (%1,4) yer aldı.
Sonuç: Bu üçüncü basamak merkezde yapılan pediatrik alerji konsültasyonları ağırlıklı olarak solunum yolu semptomları ve ilaç aşırı duyarlılığına yöneliktir. Uzman değerlendirmesi, doğru tanı konulmasını, güvenli ilaç kullanımını ve uygun tedavi planlamasını sağlamaktadır. Bu durum, yatan hasta alerji hizmetlerinin önemini ortaya koymakta olup pediatri asistanları için de önemli bir eğitim fırsatı sunmaktadır. Bu bulgular, çocuk servislerinde alerji uzmanlarının entegre bir şekilde yer almasının gerekliliğini vurgulamaktadır.

References

  • 1.Zablotsky B, Black LI, Akinbami LJ. Diagnosedallergic conditions in children aged 0–17 years:United States, 2021. Natl Health Stat Report.2023;(459):1-8.
  • 2.Özmen S, Mısırlıoğlu ED, Giniş T, et al.Consultations in pediatric allergy. Turk J Pediatr Dis. 2011;5(4):202-7.
  • 3.Wurst M, Brameli A, Krantz M, et al. Evolvingpatterns in inpatient pediatric consultations toallergy/immunology at an academic medical center.Int J Med Stud. 2024;12(3):278-83..
  • 4.Zuberbier T, Aberer W, Asero R, et al. TheEAACI/GA²LEN/EDF/WAO guideline for thedefinition, classification, diagnosis and management of urticaria. Allergy. 2018;73(7):1393-414.
  • 5.Cardona V, Ansotegui IJ, Ebisawa M, et al. WorldAllergy Organization anaphylaxis guidance 2020.World Allergy Organ J. 2020;13(10):100472.
  • 6.Brockow K, Ardern-Jones MR, Mockenhaupt M, etal. EAACI position paper on how to classifycutaneous manifestations of drug hypersensitivity.Allergy. 2019;74(1):14-27.
  • 7.Broyles AD, Banerji A, Castells M. Practicalguidance for the evaluation and management ofdrug hypersensitivity: general concepts. J AllergyClin Immunol Pract. 2020;8(9 Suppl):3-15.
  • 8.Castells M. Rapid desensitization forhypersensitivity reactions to medications. ImmunolAllergy Clin North Am. 2009;29(3):585-606.
  • 9.Muraro A, Halken S, Arshad S, et al. EAACI foodallergy and anaphylaxis guidelines. Allergy.2014;69(5):590-601.
  • 10.England RW, Ho TC, Napoli DC, Quinn JM.Inpatient consultation of allergy/immunology in atertiary care setting. Ann Allergy Asthma Immunol.2003;90(4):393-7.
  • 11.Otto HF, England RW, Quinn JM, editors.Inpatient allergy/immunology consultations in atertiary care setting. Allergy Asthma Proc.2010;31(2):165-71.
  • 12.Dietrich JJ, Quinn JM, England RW, editors.Reasons for outpatient consultation inallergy/immunology. Allergy Asthma Proc.2009;30(4):397-401.
  • 13.Quinn JM. Pediatric inpatient consultation ofallergy/immunology. Pediatr Asthma AllergyImmunol. 2000;14(4):293-9.
There are 13 citations in total.

Details

Primary Language English
Subjects Health Care Administration, Medical Education, Health Services and Systems (Other)
Journal Section Original Articles
Authors

Ahmet Selmanoğlu This is me

Gökhan Yörüsün

Cankat Genis

Fatma Nur Kuzucu This is me

Zeynep Sengul Emeksiz

Emine Dibek Mısırlıoğlu

Publication Date September 16, 2025
Submission Date July 22, 2025
Acceptance Date September 5, 2025
Published in Issue Year 2025 Volume: 52 Issue: 3

Cite

APA Selmanoğlu, A., Yörüsün, G., Genis, C., … Kuzucu, F. N. (2025). Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends. Dicle Medical Journal, 52(3), 569-576. https://doi.org/10.5798/dicletip.1785132
AMA Selmanoğlu A, Yörüsün G, Genis C, Kuzucu FN, Sengul Emeksiz Z, Dibek Mısırlıoğlu E. Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends. Dicle Medical Journal. September 2025;52(3):569-576. doi:10.5798/dicletip.1785132
Chicago Selmanoğlu, Ahmet, Gökhan Yörüsün, Cankat Genis, Fatma Nur Kuzucu, Zeynep Sengul Emeksiz, and Emine Dibek Mısırlıoğlu. “Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends”. Dicle Medical Journal 52, no. 3 (September 2025): 569-76. https://doi.org/10.5798/dicletip.1785132.
EndNote Selmanoğlu A, Yörüsün G, Genis C, Kuzucu FN, Sengul Emeksiz Z, Dibek Mısırlıoğlu E (September 1, 2025) Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends. Dicle Medical Journal 52 3 569–576.
IEEE A. Selmanoğlu, G. Yörüsün, C. Genis, F. N. Kuzucu, Z. Sengul Emeksiz, and E. Dibek Mısırlıoğlu, “Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends”, Dicle Medical Journal, vol. 52, no. 3, pp. 569–576, 2025, doi: 10.5798/dicletip.1785132.
ISNAD Selmanoğlu, Ahmet et al. “Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends”. Dicle Medical Journal 52/3 (September2025), 569-576. https://doi.org/10.5798/dicletip.1785132.
JAMA Selmanoğlu A, Yörüsün G, Genis C, Kuzucu FN, Sengul Emeksiz Z, Dibek Mısırlıoğlu E. Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends. Dicle Medical Journal. 2025;52:569–576.
MLA Selmanoğlu, Ahmet et al. “Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends”. Dicle Medical Journal, vol. 52, no. 3, 2025, pp. 569-76, doi:10.5798/dicletip.1785132.
Vancouver Selmanoğlu A, Yörüsün G, Genis C, Kuzucu FN, Sengul Emeksiz Z, Dibek Mısırlıoğlu E. Inpatient Pediatric Allergy Referrals: A One-Year Review of Consultation Trends. Dicle Medical Journal. 2025;52(3):569-76.