Year 2020, Volume 22 , Issue 1, Pages 46 - 50 2020-04-30

Evaluation and Management of Severe Childhood Anemia: A Single Center Experience
Derin Çocukluk Çağı Anemisinin Değerlendirilmesi ve Yönetimi: Tek Merkez Deneyimi

Hatice Mine ÇAKMAK [1] , Mehmet Ali SUNGUR [2] , Kenan KOCABAY [3]


Aim: The aim of this study was to determine the frequency of iron deficiency anemia in patients with severe anemia, and to investigate and compare the difference in the hematological parameters between patients with and without iron deficiency anemia.
Material and Methods: A total of 119 patients diagnosed with severe anemia between January 2012 and July 2014 were retrospectively analyzed in this study. Demographic and clinical characteristics of severe anemia patients were evaluated. Patients were evaluated in terms of iron deficiency anemia, and clinical characteristic and laboratory findings of the patients with and without iron deficiency anemia were compared.
Results: Of the 119 cases 49 (41.2%) were male and 70 (58.8%) were female, mean age was 6.7±6.2 years. Various comorbidities were present in the patients. In all patients, the group with a hemoglobin value below 6 g/dL had a significantly lower platelet count than those equal to or above 6 g/dL (p=0.037). It was found that 52 (43.7%) of all cases had iron deficiency anemia and 27 (51.9%) of them were aged 5 to 18 years. Patients with iron deficiency anemia had lower ferritin level (p<0.001) than patients without iron deficiency anemia, while platelet count was higher in patients with iron deficiency anemia (p=0.001).
Conclusion: In patients with severe anemia, a significant decrease in platelet count was found with hemoglobin value below 6 g/dL. In order to reduce the need for red blood cells transfusion, early diagnosis of iron deficiency anemia is important and iron supplementation should be given earlier.

Amaç: Bu çalışmanın amacı derin anemisi olan hastalarda demir eksikliği anemisi sıklığını belirlemek ve demir eksikliği anemisi olan ve olmayan hastalar arasında hematolojik parametrelerdeki farklılığı incelemek ve karşılaştırmaktır.
Gereç ve Yöntemler: Bu çalışmada Ocak 2012 ve Temmuz 2014 tarihleri arasında derin anemi tanısı almış olan toplam 119 hasta geriye dönük olarak incelendi. Derin anemi hastalarının demografik ve klinik özellikleri değerlendirildi. Hastalar demir eksikliği anemisi açısından değerlendirildi ve demir eksikliği anemisi olan ve olmayan hastaların klinik özellikleri ve laboratuvar bulguları karşılaştırıldı.
Bulgular: Yüz on dokuz olgunun 49 (%41,2)’u erkek, 70 (%58,8)’i kız olup ortalama yaş 6,7±6,2 yıl idi. Hastalarda çeşitli eş zamanlı hastalıklar vardı. Tüm hastalarda, hemoglobin değeri 6 gr/dL’nin altında olan grup, 6 gr/dL’ye eşit ve üstünde olanlara göre anlamlı şekilde daha düşük trombosit sayısına sahipti (p=0,037). Tüm vakaların 52 (%43,7)’sinde demir eksikliği anemisi olduğu bulundu ve bunların 27 (%51,9)’si 5 ile 18 yaş arasında idi. Demir eksikliği anemisi olan hastaların ferritin düzeyi demir eksikliği anemisi olmayan hastalara göre daha düşük (p<0,001) iken, trombosit sayısı ise demir eksikliği anemisi olan hastalarda daha yüksekti (p=0,001).
Sonuç: Derin anemili hastalarda, hemoglobin değerinin 6 g/dL’nin altında olması durumunda trombosit sayısında anlamlı düşüş saptanmıştır. Eritrosit transfüzyonu ihtiyacını azaltmak için, demir eksikliği anemisinin erken teşhisi önemlidir ve demir takviyesi daha erken yapılmalıdır.
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Primary Language en
Subjects Medicine
Journal Section Research Article
Authors

Orcid: 0000-0003-3730-0982
Author: Hatice Mine ÇAKMAK (Primary Author)
Institution: Eskişehir Şehir Hastanesi
Country: Turkey


Orcid: 0000-0001-5380-0819
Author: Mehmet Ali SUNGUR
Institution: DUZCE UNIVERSITY
Country: Turkey


Orcid: 0000-0002-4030-1145
Author: Kenan KOCABAY
Institution: DUZCE UNIVERSITY
Country: Turkey


Dates

Publication Date : April 30, 2020

Bibtex @research article { dtfd660893, journal = {Duzce Medical Journal}, issn = {}, eissn = {1307-671X}, address = {}, publisher = {Duzce University}, year = {2020}, volume = {22}, pages = {46 - 50}, doi = {10.18678/dtfd.660893}, title = {Evaluation and Management of Severe Childhood Anemia: A Single Center Experience}, key = {cite}, author = {Çakmak, Hatice Mine and Sungur, Mehmet Ali and Kocabay, Kenan} }
APA Çakmak, H , Sungur, M , Kocabay, K . (2020). Evaluation and Management of Severe Childhood Anemia: A Single Center Experience . Duzce Medical Journal , 22 (1) , 46-50 . DOI: 10.18678/dtfd.660893
MLA Çakmak, H , Sungur, M , Kocabay, K . "Evaluation and Management of Severe Childhood Anemia: A Single Center Experience" . Duzce Medical Journal 22 (2020 ): 46-50 <https://dergipark.org.tr/en/pub/dtfd/issue/53917/660893>
Chicago Çakmak, H , Sungur, M , Kocabay, K . "Evaluation and Management of Severe Childhood Anemia: A Single Center Experience". Duzce Medical Journal 22 (2020 ): 46-50
RIS TY - JOUR T1 - Evaluation and Management of Severe Childhood Anemia: A Single Center Experience AU - Hatice Mine Çakmak , Mehmet Ali Sungur , Kenan Kocabay Y1 - 2020 PY - 2020 N1 - doi: 10.18678/dtfd.660893 DO - 10.18678/dtfd.660893 T2 - Duzce Medical Journal JF - Journal JO - JOR SP - 46 EP - 50 VL - 22 IS - 1 SN - -1307-671X M3 - doi: 10.18678/dtfd.660893 UR - https://doi.org/10.18678/dtfd.660893 Y2 - 2020 ER -
EndNote %0 Düzce Tıp Fakültesi Dergisi Evaluation and Management of Severe Childhood Anemia: A Single Center Experience %A Hatice Mine Çakmak , Mehmet Ali Sungur , Kenan Kocabay %T Evaluation and Management of Severe Childhood Anemia: A Single Center Experience %D 2020 %J Duzce Medical Journal %P -1307-671X %V 22 %N 1 %R doi: 10.18678/dtfd.660893 %U 10.18678/dtfd.660893
ISNAD Çakmak, Hatice Mine , Sungur, Mehmet Ali , Kocabay, Kenan . "Evaluation and Management of Severe Childhood Anemia: A Single Center Experience". Duzce Medical Journal 22 / 1 (April 2020): 46-50 . https://doi.org/10.18678/dtfd.660893
AMA Çakmak H , Sungur M , Kocabay K . Evaluation and Management of Severe Childhood Anemia: A Single Center Experience. Duzce Medical Journal. 2020; 22(1): 46-50.
Vancouver Çakmak H , Sungur M , Kocabay K . Evaluation and Management of Severe Childhood Anemia: A Single Center Experience. Duzce Medical Journal. 2020; 22(1): 46-50.
IEEE H. Çakmak , M. Sungur and K. Kocabay , "Evaluation and Management of Severe Childhood Anemia: A Single Center Experience", Duzce Medical Journal, vol. 22, no. 1, pp. 46-50, Apr. 2020, doi:10.18678/dtfd.660893