Genista carinalis Bitkisinin Uçucu Bileşiklerinin Kimyasal Bileşenleri ve Antibakteriyel Aktivitesi

Abstract

Uçucu yağlar, bitki kimyasında önemli bir rol oynamaktadır. Doğal ürünler, Orta Çağ'dan beri antiviral, antibakteriyel, antiparazitik, antifungal, böcek öldürücü, tıbbi ve kozmetik uygulamalarında yaygın olarak kullanılmaktadır. Bu çalışmadaki amacımız, Trakya bölgesinde yetişen Genista carinalis Griseb. (Fabaceae) bitkisinin uçucu bileşenlerini GC-MS yöntemi ile araştırmak ve ham ekstrelerinde antibakteriyel aktivitesini belirlemektir. G. carinalis bitkisinden elde edilen n-hekzan ekstresinin uçucu bileşenleri, GC-MS yöntemi kullanılarak araştırıldı. G. carinalis'in uçucu bileşenleri üzerine yaptığımız araştırma sonucunda elli iki adet biyoaktif bileşen tespit edilmiştir. Çalışmada denenen hem Gram-pozitif hem de Gram-negatif bakteriler üzerinde en yüksek antibakteriyel etki G. carinalis’in etil asetat ekstresi ile elde edilmiştir. Bu ekstrenin Gram-pozitif bakterilere etkisinn Gram-negatiflere oranla daha yüksek olduğu gözlenmiştir.

Keywords

• Genista
• Genista carinalis
• Fabaceae
• Uçucu yağ
• Antibakteriyel aktivite

Chemical Composition and Antibacterial Activity of Volatile Compounds Genista carinalis Plant

Abstract

Essential oils play a significant role in the plant chemistry. Natural products have been widely used in antiviral, antibacterial, antiparasitic, antifungal, insecticidal, medicinal and cosmetic applications since the Middle Age. Our aim in this study was to investigate the volatile components of the Genista carinalis Griseb. (Fabaceae) plant grown in the Trakya region by GC-MS method and to determine the antibacterial activity of the raw extracts. Volatile components of n-hexane extract from the plant G. carinalis were investigated using the GC-MS method. As a result of our research on the volatile components of G. carinalis, fifty-two bioactive components were identified. The ethyl acetate extract of G. carinalis was the most effective on both Gram-positive and Gram-negative bacteria tested, with higher antibacterial activity against Gram positive bacteria.

Keywords

• Genista
• Genista carinalis
• Fabaceae
• Essential Oil
• Antibacterial activity

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