Oküler Dokularda Oksidatif Stres ve Potasyum İyonunun (K+) Tetiklediği Hastalıklarda Erken Teşhis İmkâni Sağlayan Kontakt Lens

Year 2024, , 631 - 641, 29.04.2024

Yaşar Şen

https://doi.org/10.29130/dubited.1352248

Abstract

Çalışmada, bir doktorun yerini alabilecek bir lens tasarlamak için sensör teknolojisi kullanıldı. Erken teşhis için silikon hidrojel lens olan Lotrafilcon A üzerine yerleştirilecek oksidatif stres sensörü, (K+) iyon sensörü ve basınç sensörünün yanı sıra kullanıcının kendi başına kullanabileceği bir kayıt ve görüntüleme cihazından oluşur, 24 saat kayıt yapar ve gerekirse uyarı verir. Ek olarak, harici bir kablosuz güç aktarım cihazı aracılığıyla veri iletimi için sensörlere güç sağlanacaktır. Kullanılan oksidatif stres sensörü ile göz yapılarında oksidatif stres saptanır, hastada diyabetik retinopati, glokom ve katarakt için anormal bir durumun ortaya çıkabileceği anlaşılır. Aynı şekilde (K +) iyon sensörü de oküler hücrelerdeki (K +) iyon konsantrasyonunu tespit eder, konsantrasyonun arttığı anormal durumları tespit eder. Kullanılacak basınç sensörü ile glokom tanısı alan hastaların basıncı kontrol altında tutulur. Oluşabilecek hastalıkların erken teşhisi, eğer bir hastalık varsa hastalığın sürekli izlenmesi ve kontrolü sağlanacaktır. Bu, kullanıcının sürekli hastaneye gitmesini önlerken aynı zamanda iş yükünü de azaltacaktır.

Keywords

Katarakt, Kontakt lens, Diyabetik retinopati, Migren, Oksidatif stres, Potasyum iyon (K+) sensörü

Contact Lens that Enabled Early Diagnosis for Diseases Induced by Oxidative Stress and Potassium Ion (K+) in Ocular Tissues

Abstract

The present study used sensor technology to design a lens that could replace a docto.r It consists of an oxidative stress sensor, a (K+) ion sensor and a pressure sensor placed on a Lotrafilcon A silicone hydrogel lens for early diagnosis, as well as a recording and display device that the user can use on their own, recording 24 hours a day and alerting when needed. Additionally, power will be provided to the sensors for data transmission via an external wireless power transfer device. The oxidative stress sensor detects oxidative stress in the structures of the eye and indicates that the patient may have an abnormal condition like diabetic retinopathy, glaucoma and cataracts. Likewise, the (K +) ion sensor detects the (K +) ion concentration in the ocular cells and detects abnormal conditions where the concentration is elevated. The pressure sensor allows the intraocular pressure of patients diagnosed with glaucoma to be kept under control. This way, diseases can be diagnosed early, and continuous monitoring and control of the disease will be ensured. This will prevent the user from having to make frequent visits to the hospital, while also reducing the workload.

Keywords

Cataract, Contact lens, Diabetic retinopathy, Migraine, Oxidative stress, Potassium ion (K+) sensor

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