Research Article

Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini

Volume: 6 Number: 4 August 1, 2018
Cumhur Ökçelik , Ece Ergun , Ümit Ergun *
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Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini

Abstract

Antiseptik etkili klorheksidini, antienflamatuar etkili enoksolonu ve lokal etkili benzokaini bir arada içeren ve bu içeriğiyle ağız-boğaz bölgesindeki lokal irritasyonlara bağlı rahatsızlıkları ortadan kaldırmaya yardımcı olarak kullanılan Anzibel pastillerin maliyet, iş yükü ve zaman açısından daha ekonomik olması nedeniyle miktar tayini analizinin tek bir HPLC yöntemi geliştirilerek, gerekli validasyon çalışmaları tamamlanmıştır. Analizlerde 25°C'de ACE 5 C18 4.6 x 150 mm, 5mm kolon, 250nm’de dalga boyunda 0.01 M KH2PO4 ‘ın fosforik asit ile pH 3.0± 0.05’e ayarlanmış tampon çözeltisi ve asetonitril kullanılmıştır. Sistem uygunluk, doğruluk ve doğrusallık parametreleri çalışılmış ve kabul edilebilir sonuçlar elde edilmiştir.

Keywords

Klorheksidin, enoksolon, benzokain, HPLC

References

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Details

Primary Language

Turkish

Subjects

Engineering

Journal Section

Research Article

Authors

Cumhur Ökçelik This is me
Türkiye

Ece Ergun This is me
Türkiye

Publication Date

August 1, 2018

Submission Date

May 24, 2018

Acceptance Date

June 19, 2018

Published in Issue

Year 2018 Volume: 6 Number: 4

DOI

https://doi.org/10.29130/dubited.426743

IZ

https://izlik.org/JA75KE99CE

Cite

RIS / Bibtex
APA
Ökçelik, C., Ergun, E., & Ergun, Ü. (2018). Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini. Duzce University Journal of Science and Technology, 6(4), 1200-1210. https://doi.org/10.29130/dubited.426743
AMA
1.Ökçelik C, Ergun E, Ergun Ü. Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini. DUBİTED. 2018;6(4):1200-1210. doi:10.29130/dubited.426743
Chicago
Ökçelik, Cumhur, Ece Ergun, and Ümit Ergun. 2018. “Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini”. Duzce University Journal of Science and Technology 6 (4): 1200-1210. https://doi.org/10.29130/dubited.426743.
EndNote
Ökçelik C, Ergun E, Ergun Ü (August 1, 2018) Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini. Duzce University Journal of Science and Technology 6 4 1200–1210.
IEEE
[1]C. Ökçelik, E. Ergun, and Ü. Ergun, “Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini”, DUBİTED, vol. 6, no. 4, pp. 1200–1210, Aug. 2018, doi: 10.29130/dubited.426743.
ISNAD
Ökçelik, Cumhur - Ergun, Ece - Ergun, Ümit. “Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini”. Duzce University Journal of Science and Technology 6/4 (August 1, 2018): 1200-1210. https://doi.org/10.29130/dubited.426743.
JAMA
1.Ökçelik C, Ergun E, Ergun Ü. Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini. DUBİTED. 2018;6:1200–1210.
MLA
Ökçelik, Cumhur, et al. “Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini”. Duzce University Journal of Science and Technology, vol. 6, no. 4, Aug. 2018, pp. 1200-1, doi:10.29130/dubited.426743.
Vancouver
1.Cumhur Ökçelik, Ece Ergun, Ümit Ergun. Anzibel Pastillerde Enoksolon-Benzokain-Klorheksidin HPLC Miktar Tayini. DUBİTED. 2018 Aug. 1;6(4):1200-1. doi:10.29130/dubited.426743