Research Article

Self -Assembled Monolayers with Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors

Volume: 7 Number: 3 July 31, 2019
Zehra Banu Bahsi Oral *
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Self -Assembled Monolayers with Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors

Abstract

Alkanethiol self-assembled monolayers (SAMs) with Peptide Nucleic Acid (PNA) were proposed as a novel probe design in electrochemical biosensors. This paper investigates the optimization of PNA probe by using two different concentrations of SAMs, immobilization temperature, and two-stage immobilization process. Alkanethiol self-assembled monolayers with PNA probe immobilization and cDNA (complementary DNA) hybridization were measured via AC voltammetry method. The small negative shift in formal potential (-17 mV) was occurred after cDNA hybridization at high ionic strength concentration.

Keywords

Alkanethiol self-assembled monolayers,PNA,electrochemical biosensors,AC voltammetry

References

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Details

Primary Language

English

Subjects

Engineering

Journal Section

Research Article

Authors

Publication Date

July 31, 2019

Submission Date

April 26, 2019

Acceptance Date

July 17, 2019

Published in Issue

Year 2019 Volume: 7 Number: 3

DOI

https://doi.org/10.29130/dubited.558155

IZ

https://izlik.org/JA73EL32FP

Cite

RIS / Bibtex
APA
Bahsi Oral, Z. B. (2019). Self -Assembled Monolayers with Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors. Duzce University Journal of Science and Technology, 7(3), 1806-1812. https://doi.org/10.29130/dubited.558155
AMA
1.Bahsi Oral ZB. Self -Assembled Monolayers with Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors. DUBİTED. 2019;7(3):1806-1812. doi:10.29130/dubited.558155
Chicago
Bahsi Oral, Zehra Banu. 2019. “Self -Assembled Monolayers With Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors”. Duzce University Journal of Science and Technology 7 (3): 1806-12. https://doi.org/10.29130/dubited.558155.
EndNote
Bahsi Oral ZB (July 1, 2019) Self -Assembled Monolayers with Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors. Duzce University Journal of Science and Technology 7 3 1806–1812.
IEEE
[1]Z. B. Bahsi Oral, “Self -Assembled Monolayers with Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors”, DUBİTED, vol. 7, no. 3, pp. 1806–1812, July 2019, doi: 10.29130/dubited.558155.
ISNAD
Bahsi Oral, Zehra Banu. “Self -Assembled Monolayers With Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors”. Duzce University Journal of Science and Technology 7/3 (July 1, 2019): 1806-1812. https://doi.org/10.29130/dubited.558155.
JAMA
1.Bahsi Oral ZB. Self -Assembled Monolayers with Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors. DUBİTED. 2019;7:1806–1812.
MLA
Bahsi Oral, Zehra Banu. “Self -Assembled Monolayers With Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors”. Duzce University Journal of Science and Technology, vol. 7, no. 3, July 2019, pp. 1806-12, doi:10.29130/dubited.558155.
Vancouver
1.Zehra Banu Bahsi Oral. Self -Assembled Monolayers with Peptide Nucleic Acid (PNA) Probe to Develop Electrochemical Biosensors. DUBİTED. 2019 Jul. 1;7(3):1806-12. doi:10.29130/dubited.558155