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Dişi Köpeklerde Ovariohisterektomi Öncesi ve Sonrası Bazı Hematolojik ve Biyokimyasal Parametrelerin Değerlendirilmesi

Year 2019, Volume: 12 Issue: 2, 93 - 96, 31.12.2019

Abstract

Bu
çalışmanın amacı, ovariohisterektominin klinik olarak sağlıklı köpeklerde
hematolojik ve biyokimyasal parametreler üzerine olan etkisini ortaya koymak ve
bu parametrelerin sıklıkla yapılan bu ameliyatın herhangi bir komplikasyonunu
tanımlamak için kullanılıp kullanılamayacağını belirlemekti. Çalışmada gebe
olmayan 8 sağlıklı dişi köpek (1-3 yaş) kullanıldı. Kan örnekleri
ovariohisterektomi yapılmadan hemen önce ve OVH sonrası 1 ile 7 gün arasında
toplandı. Hematolojik parametreler ve AST, ALT, CK-MB, CRP, CHOL, TG, LDL ve
HDL seviyeleri belirlendi. Operasyon öncesi ve sonrası istatistiksel
farklılıklar, WBC, RBC, AST, CRP ve TG seviyelerinde bulundu. Diğer
biyokimyasal parametrelerde anlamlı bir farklılık bulunmadı. Çalışmanın
sonuçları, sağlıklı köpeklerin bazı hematolojik ve biyokimyasal
parametrelerinin anestezi ve ameliyattan etkilendiğini ortaya koydu.

References

  • 1. Reichler IM. (2009). Gonadectomy in cats and dogs: a review of risks and benefits. Reprod Domest Anim. 44: 29-35.
  • 2. Burrow R, Batchelor D, Cripps P. (2005). Complications observed during and after ovariohysterectomy of 142 bitches at a veterinary teaching hospital. Vet Rec. 157:829–33.
  • 3. Desborough JP. (2000). The stress response to trauma and surgery. Br J Anaesth. 85:109-17.
  • 4. Linde-Sipman JS, Hellebrekers LJ, Lagerwey E. (1992). Myocardial damage in cats that died after anaesthesia. Vet Quartely. 15:91-4.
  • 5. Christensen MB, Eriksen T, Kjelgaard-Hansen M. (2015). Creactive protein: quantitative marker of surgical trauma and post-surgical complications in dogs: a systematic review. Acta Vet Scand. 57: 71.
  • 6. Petrič AD, Lukman T, Verk B, Svete AN. (2018). Systemic infammation in dogs with advanced-stage heart failure. Acta Vet Scand. 60:20.
  • 7. Coodley EL. (1970). Diagnosic Enzymology. WB. Saunders Co, Philadelphia, USA.
  • 8. Reimann MJ, Ljungvall I, Hillström A, et al. (2016). Increased serum C-reactive protein concentrations in dogs with congestive heart failure due to myxomatous mitral valve disease. Vet J. 209: 113–8.
  • 9. Moran C, Ni Bhuinneain M, Geary M, et al. (2001). Myocardial ischaemia in normal patients undergoing elective Caesarean section: a peripartum assessment. Anaesthesia. 56: 1051-1058.
  • 10. Nevill B, Leisewitz A, Goddard A, Thompson P. (2010). An evaluation of changes over time in serum creatine kinase activity and C-reactive protein concentration in dogs undergoing hemilaminectomy or ovariohysterectomy. J S Afr Vet Assoc. 81:22–26.
  • 11. Baisan RA, Rosa AD, Loría A, Vulpe V, Piantedosi D. (2016). Cardiac biomarkers in clinical practice of dog and cat – a review. Human & Veterinary Medicine. 8:50-58.
  • 12. Gunay A, Gunes N, Gunay U. (2011). Effect of ovariohysterectomy on lipid peroxidation and levels of some antioxidants and biochemical parameters in bitches. Bull Vet Inst Pulawy. 55: 695-698.
  • 13. Moldal ER, Kjelgaard‑Hansen MJ, Peeters ME, Nødtvedt A, Kirpensteijn J. (2018). C‑reactive protein, glucose and iron concentrations are significantly altered in dogs undergoing open ovariohysterectomy or ovariectomy. Acta Vet Scand. 60:32.
  • 14. Krimins RA, Ko JC, Weil AB et al. (2012) Hemodynamic effects in dogs after intramuscular administration of a combination of dexmedetomidine-butorphanol-tiletamine-zolazepam or dexmedetomidine-butorphanol-ketamine. Am J Vet Res. 73:1363–1370.
  • 15. Franco LG, Wilges CHM, Junior DP et al. (2018). Effects of ketamine constant rate infusions on cardiac biomarkers and cardiac function in dogs. Veterinary Anaesthesia and Analgesia. 45(3):250-259.
  • 16. Dąbrowski R, Wawron W. (2014). Acute-phase response in monitoring postoperative recovery in bitches after ovariohysterectomy. Ann Anim Sci. 14(2 ):287–295.
  • 17. Bauer JE. (2004). Lipoprotein-mediated transport of dietary and synthesized lipids and lipid abnormalities of dogs and cats. J Am Vet Med Assoc. 224: 668–675.

Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs

Year 2019, Volume: 12 Issue: 2, 93 - 96, 31.12.2019

Abstract

The
present study was conducted to identify the effect of ovariohysterectomy (OVH) on
routine measures of hematological and biochemical variables in clinically
healthy dogs. Non-pregnant 8 healthy female dogs were contained in the study. Blood
samples were collected immediately before ovariohysterectomy and between 1 to 7
days throughout after OVH. Hematological parameters and levels of AST, ALT, CK-MB,
CRP, CHOL, TG, LDL, and HDL were determined. 
The statistical differences were found in the WBC, RBC, AST, CRP, and TG
levels between the pre and postoperative. There were no significant differences
of other biochemical parameters. The results of the study revealed that some
hematological and biochemical parameters of healthy dogs are affected by
anesthesia and surgery.

References

  • 1. Reichler IM. (2009). Gonadectomy in cats and dogs: a review of risks and benefits. Reprod Domest Anim. 44: 29-35.
  • 2. Burrow R, Batchelor D, Cripps P. (2005). Complications observed during and after ovariohysterectomy of 142 bitches at a veterinary teaching hospital. Vet Rec. 157:829–33.
  • 3. Desborough JP. (2000). The stress response to trauma and surgery. Br J Anaesth. 85:109-17.
  • 4. Linde-Sipman JS, Hellebrekers LJ, Lagerwey E. (1992). Myocardial damage in cats that died after anaesthesia. Vet Quartely. 15:91-4.
  • 5. Christensen MB, Eriksen T, Kjelgaard-Hansen M. (2015). Creactive protein: quantitative marker of surgical trauma and post-surgical complications in dogs: a systematic review. Acta Vet Scand. 57: 71.
  • 6. Petrič AD, Lukman T, Verk B, Svete AN. (2018). Systemic infammation in dogs with advanced-stage heart failure. Acta Vet Scand. 60:20.
  • 7. Coodley EL. (1970). Diagnosic Enzymology. WB. Saunders Co, Philadelphia, USA.
  • 8. Reimann MJ, Ljungvall I, Hillström A, et al. (2016). Increased serum C-reactive protein concentrations in dogs with congestive heart failure due to myxomatous mitral valve disease. Vet J. 209: 113–8.
  • 9. Moran C, Ni Bhuinneain M, Geary M, et al. (2001). Myocardial ischaemia in normal patients undergoing elective Caesarean section: a peripartum assessment. Anaesthesia. 56: 1051-1058.
  • 10. Nevill B, Leisewitz A, Goddard A, Thompson P. (2010). An evaluation of changes over time in serum creatine kinase activity and C-reactive protein concentration in dogs undergoing hemilaminectomy or ovariohysterectomy. J S Afr Vet Assoc. 81:22–26.
  • 11. Baisan RA, Rosa AD, Loría A, Vulpe V, Piantedosi D. (2016). Cardiac biomarkers in clinical practice of dog and cat – a review. Human & Veterinary Medicine. 8:50-58.
  • 12. Gunay A, Gunes N, Gunay U. (2011). Effect of ovariohysterectomy on lipid peroxidation and levels of some antioxidants and biochemical parameters in bitches. Bull Vet Inst Pulawy. 55: 695-698.
  • 13. Moldal ER, Kjelgaard‑Hansen MJ, Peeters ME, Nødtvedt A, Kirpensteijn J. (2018). C‑reactive protein, glucose and iron concentrations are significantly altered in dogs undergoing open ovariohysterectomy or ovariectomy. Acta Vet Scand. 60:32.
  • 14. Krimins RA, Ko JC, Weil AB et al. (2012) Hemodynamic effects in dogs after intramuscular administration of a combination of dexmedetomidine-butorphanol-tiletamine-zolazepam or dexmedetomidine-butorphanol-ketamine. Am J Vet Res. 73:1363–1370.
  • 15. Franco LG, Wilges CHM, Junior DP et al. (2018). Effects of ketamine constant rate infusions on cardiac biomarkers and cardiac function in dogs. Veterinary Anaesthesia and Analgesia. 45(3):250-259.
  • 16. Dąbrowski R, Wawron W. (2014). Acute-phase response in monitoring postoperative recovery in bitches after ovariohysterectomy. Ann Anim Sci. 14(2 ):287–295.
  • 17. Bauer JE. (2004). Lipoprotein-mediated transport of dietary and synthesized lipids and lipid abnormalities of dogs and cats. J Am Vet Med Assoc. 224: 668–675.
There are 17 citations in total.

Details

Primary Language English
Journal Section Research
Authors

Ebru Karakaya Bilen 0000-0003-4837-1858

Publication Date December 31, 2019
Acceptance Date November 2, 2019
Published in Issue Year 2019 Volume: 12 Issue: 2

Cite

APA Karakaya Bilen, E. (2019). Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs. Dicle Üniversitesi Veteriner Fakültesi Dergisi, 12(2), 93-96.
AMA Karakaya Bilen E. Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs. Dicle Üniv Vet Fak Derg. December 2019;12(2):93-96.
Chicago Karakaya Bilen, Ebru. “Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs”. Dicle Üniversitesi Veteriner Fakültesi Dergisi 12, no. 2 (December 2019): 93-96.
EndNote Karakaya Bilen E (December 1, 2019) Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs. Dicle Üniversitesi Veteriner Fakültesi Dergisi 12 2 93–96.
IEEE E. Karakaya Bilen, “Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs”, Dicle Üniv Vet Fak Derg, vol. 12, no. 2, pp. 93–96, 2019.
ISNAD Karakaya Bilen, Ebru. “Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs”. Dicle Üniversitesi Veteriner Fakültesi Dergisi 12/2 (December 2019), 93-96.
JAMA Karakaya Bilen E. Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs. Dicle Üniv Vet Fak Derg. 2019;12:93–96.
MLA Karakaya Bilen, Ebru. “Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs”. Dicle Üniversitesi Veteriner Fakültesi Dergisi, vol. 12, no. 2, 2019, pp. 93-96.
Vancouver Karakaya Bilen E. Evaluation of Some Hematological and Biochemical Parameters Pre and Post Ovariohysterectomy in Dogs. Dicle Üniv Vet Fak Derg. 2019;12(2):93-6.

DANIŞMA KURULU
Prof. Dr. Abit AKTAŞ, İstanbul Üniversitesi-Cerrahpaşa
Prof. Dr. Yılmaz ARAL, Ankara Üniversitesi
Prof. Dr. Ali ARSLAN, Fırat Üniversitesi, Elazığ
Prof. Dr. M. Sedat BARAN, Dicle Üniversitesi, Diyarbakır
Prof. Dr. Cengiz CEYLAN, Balıkesir Üniversitesi
Prof. Dr. Ahmet ÇAKIR, Ankara Üniversitesi
Prof. Dr. Burhan ÇETİNKAYA, Fırat Üniversitesi, Elazığ
Prof. Dr. Ülker EREN, Adnan Menderes Üniversitesi, Aydın
Prof. Dr. Abdurrahman GÜL, Bingöl Üniversitesi
Prof. Dr. Hakki KARA, Cumhuriyet Üniversitesi, Sivas
Prof. Dr. Narin LİMAN, Erciyes Üniversitesi, Kayseri
Prof. Dr. Abdullah ÖZEN, Fırat Üniversitesi, Elazığ
Prof. Dr. Ayşe SERBEST, Uludağ Üniversitesi, Bursa
Prof. Dr. Kazım ŞAHİN, Fırat Üniversitesi, Elazığ
Prof. Dr. Tekin ŞAHİN, Siirt Üniversitesi
Prof. Dr. Nihat ŞINDAK, Siirt Üniversitesi
Prof. Dr. Muzaffer TAŞ, Namık Kemal Üniversitesi, Tekirdağ
Prof. Dr. Necati TİMURKAN Fırat Üniversitesi, Elazığ
Prof. Dr. Emine ÜNSALDI, Fırat Üniversitesi, Elazığ
Prof. Dr. Murat YILDIRIM, Kırıkkale Üniversitesi
Doç. Dr. M. Osman ATLI, Harran Üniversitesi, Şanlıurfa
Doç. Dr. Bülent ELİTOK, Afyon Kocatepe Üniversitesi
Doç. Dr. Serkan ERDOĞAN, Namık Kemal Üniversitesi, Tekirdağ
Dr. Öğr. Üyesi Zelal KARAKOÇ, Dicle Üniversitesi, Diyarbakır
Dr. Öğr. Üyesi Ersin UYSAL, Dicle Üniversitesi, Diyarbakır
*Not: Yayın ve Danışma Kurulu Üyeleri alfabetik sıraya göre dizilmiştir.