-

Abstract

As the women participation in the business life increased, the age of pregnancy advanced; therefore the possibility ofover cancers which tend to increase with ageing, advanced in women who have not finished fertility. In over cancerwhose primary treatment is surgery, the patient in the reproductive period goes through menopause as a result of oversbeing taken out and this causes psychological and physical problems. For this reason protective methods started comingto the forefront in over cancer. We aimed presenting fertility protecting approaches in early epithelial over cancer inconjunction with up-to-date literature in our review.

Keywords

• Epithelial ovarian cancer; fertility-sparing surgery.

Erken Evre Epitelyal Over Kanserinde Fertilite Koruyucu Cerrahi

Abstract

Kadınların çalışma hayatında daha aktif rol almasıyla çocuk doğurma yaşı ilerlemiş, dolayısıyla ilerleyen yaşla artma eğilimi gösteren over kanserlerinin henüz fertilitesini tamamlamış kadınlarda görülme ihtimali artmıştır. Primer tedavisi cerrahi olan over kanserinde overlerin alınmasıyla reproduktif dönemdeki hasta menopoza girmekte; bu da ruhsal ve fiziksel problemlere yol açmaktadır. Bu nedenle over kanserinde fertilite koruyucu yöntemler ön plana çıkmaya başlamıştır. Derlememizde erken evre epitelyal over kanserindeki fertilite koruyucu yaklaşımları güncel literatür eşliğinde sunmayı amaçladık.

Keywords

• Epitelyal over kanseri; fertilite koruyucu cerrahi

References

1. 1- Heinz APM, Odicino F, Maisonneuve P, Quinn MA, Benedet JL, Creasman WT, et al. Carcinoma of the ovary. Int J Gynecol Obstet. 2006; 95(Suppl 1): s161 2- Heffner LJ. Advanced maternal age – how old is too old? N Engl J Med. 2004; 351(19): 1927-9. 3- Sugiyama T, Kamura T, Kigawa J, Terakawa N, Kikuchi Y, Kita T, et al. Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy. Cancer. 2000; 88(11): 2584-9. 4- Zanetta G, Chiari S, Rota S, Bratina G, Maneo A, Torri V, et al. Conservative surgery for stage 1 ovarian carcinoma in women of childbearing age. Br J Obstet Gynaecol. 1997; 104(9): 1030-5. 5- Raspagliesi F, Fontanelli R, Paladini D, Di Re EM. Conservative surgery in high-risk epithelial ovarian carcinoma. J Am Coll Surg. 1997; 185(5): 457-60. 6- Morice P, Leblanc E, Rey A, Baron M, Querleu D, Blanchot J, et al. Conservative treatment in epithelial ovarian cancer: results of a multicentre study of the GCCLCC (Groupe des Chirurgiens de Centre de Lutte Contre le Cancer) and SFOG (Société Francaise d'Oncologie Gynécologique). Hum Reprod. 2005; 20(5): 1379-85. 7- Marpeu O, Schilder J, Zafrani Y, Uzan C, Gouy S, Lhomme C, et al. Prognosis of Patients Who Relapse after Fertility-Sparing Surgery in Epithelial Ovarian Cancer. Annals of Surgical Oncology. 2008; 15(2): 478 8- Satoh T, Hatae M, Watanabe Y, Yaegashi N, Ishiko O, Kodama S, et al. Outcomes of fertility-sparing surgery for stage I epithelial ovarian cancer: a proposal for patient selection. J Clin Oncol. 2010; 28(10): 1727-32. 9- Kajiyama H, Shibata K, Suzuki S, Ino K, Nawa A, Kawai M, et al. Fertility sparing surgery in young women with invasive epithelial ovarian cancer. The Journal of Cancer Surgery. 2010; 36(4): 404-8. 10- Hu J, Zhu L, Liang Z, Meng Y, Guo H, Qu P, et al. Clinical outcomes of fertility-sparing treatments in young patients with epithelial ovarian carcinoma. Journal of Zhejiang University-science B. 2011; 12(10): 787-95. 11- Fruscio R, Corso S, Ceppi L, Garavaglia D, Garbi A, Floriani I, et al. Conservative management of earlystage epithelial ovarian cancer: results of a large retrospective series. Ann Oncol. 2013; 24(1): 138-44. 12-Morice P, Denschlag D, Rodolakis A, Reed N, Schneider A, Kesic V, et al. Fertility Task Force of the European Society of Gynecologic Oncology. Recommendations of the Fertility Task Force of the European Society of Gynecologic Oncology about the conservative management of ovarian malignant tumors. Int J Gynecol Cancer. 2011; 21(5): 951-63. 13-Moore MM, Tewari K, Rose GS, Fruehauf JP, DiSaia PJ. Long term consequences following conservative management of epithelial ovarian cancer in an infertile patient. Gynecol Oncol.1999; 73(3): 452-4.