The Global Knowledge Architecture of Streptococcus mutans: A Bibliometric Analysis

Merve Yıldırım Üçüncü; Musa Kazım Üçüncü

doi:10.62243/edr.1891019

The Global Knowledge Architecture of Streptococcus mutans: A Bibliometric Analysis

Abstract

Aim This study aims to elucidate the intellectual structure, evolution, and global research trends of the literature published on Streptococcus mutans, a microorganism that plays a pivotal role in the etiology of dental caries, through comprehensive bibliometric analysis.Material and method A search conducted in the Web of Science Core Collection (WOSCC) database, focusing on "Streptococcus mutans" and "Dentistry," yielded 4,975 publications. The dataset was analyzed using the R-based Bibliometrix and Biblioshiny software packages, examining patterns of authorship, leading journals, contributing countries, citation networks, and keyword clusters. Results Analyses conducted for the period 1980–2025 demonstrate that the literature exhibits a compound annual growth rate of 4.50%. The Journal of Dental Research emerges as the most influential publication venue, boasting both the highest h-index (77) and total citation count (20,710). Bowen WH is identified as the most prolific author (57 articles; h-index: 30), while Koo H holds the greatest influence within the local citation network (824 local citations). Country-level analyses reveal a robust global collaboration network dominated by the United States, China, and Brazil. Sichuan University stands out as the most productive affiliation (323 articles). Keyword cloud and network analyses substantiate that research efforts predominantly cluster around two principal thematic domains: clinical caries etiology and prevention, and biofilm mechanisms/materials science. Conclusion Research on S. mutans manifests a multidisciplinary character, having evolved from classical microbiological paradigms to contemporary genomic and nanotechnological applications. By mapping the field’s intellectual landscape, this study furnishes researchers with an evidence based framework to guide future strategic investigations.

Keywords

References

Samaranayake, L., Bandara, N., & Pesee, S. (2021). Oral biofilms: What are they? In A. C. Ionescu & S. Hahnel (Eds.), Oral biofilms and modern dental materials (1st ed., p. 4). Springer Nature.
Dahlén, G. (2025). The oral microbiome – Composition, acquisition, establishment, and maturation. In O. Fejerskov & B. Nyvad (Eds.), Dental caries: The disease and its clinical management (4th ed., p. 118). John Wiley & Sons Ltd.
Nyvad, B., & Kilian, M. (1987). Microbiology of the early colonization of human enamel and root surfaces in vivo. European Journal of Oral Sciences, 95(5), 369–380.
Baker, J. L., Faustoferri, R. C., & Quivey, R. G., Jr. (2016). Acid-adaptive mechanisms of Streptococcus mutans—The more we know, the more we don’t. Molecular Oral Microbiology, 32(2), 107.
Dashper, S. G., & Reynolds, E. C. (1992). pH regulation by Streptococcus mutans. Journal of Dental Research, 71(5), 1159–1165.
Takahashi, N., & Nyvad, B. (2025). Functions of the oral microbiome in caries and how they can be controlled. In O. Fejerskov & B. Nyvad (Eds.), Dental caries: The disease and its clinical management (4th ed., p. 137). John Wiley & Sons Ltd.
Forssten, S. D., Björklund, M., & Ouwehand, A. C. (2010). Streptococcus mutans, caries and simulation models. Nutrients, 2(3), 290–298.
Bedoya-Correa, C. M., Rincón Rodríguez, R. J., & Parada-Sanchez, M. T. (2019). Genomic and phenotypic diversity of Streptococcus mutans. Journal of Oral Biosciences, 61(1), 22–31.

Matsumoto-Nakano, M. (2018). Role of Streptococcus mutans surface proteins for biofilm formation. Japanese Dental Science Review, 54(1), 22–29.
Nguyen, M., Dinis, M., Lux, R., Shi, W., & Tran, N. C. (2022). Correlation between Streptococcus mutans levels in dental plaque and saliva of children. Journal of Oral Science, 64(4), 290–293.
Tabchoury, C. P. M., Sousa, M. C. K., Arthur, R. A., Mattos-Graner, R. O., Del Bel Cury, A. A., & Cury, J. A. (2008). Evaluation of genotypic diversity of Streptococcus mutans using distinct arbitrary primers. Journal of Applied Oral Science, 16, 403–407.
Ucuncu, M. Y., Ucuncu, M. K., Karacan, I., & Topcuoglu, N. (2025). Genome resequencing and comparative analysis of Streptococcus mutans in adults with high and low caries risk. Scientific Data, 12(1), 313.
Argimón, S., & Caufield, P. W. (2011). Distribution of putative virulence genes in Streptococcus mutans strains does not correlate with caries experience. Journal of Clinical Microbiology, 49(3), 984–992.
Lemos, J. A., Palmer, S. R., Zeng, L., Wen, Z. T., Kajfasz, J. K., Freires, I. A., et al. (2019). The biology of Streptococcus mutans. Microbiology Spectrum, 7(1).
Kumar, R. (2025). Bibliometric analysis: Comprehensive insights into tools, techniques, applications, and solutions for research excellence. Spectrum of Engineering and Management Sciences, 3(1), 45–62.
Aria, M., & Cuccurullo, C. (2017). Bibliometrix: An R-tool for comprehensive science mapping analysis. Journal of Informetrics, 11(4), 959–975.
Ionescu, A. C., & Brambilla, E. (2021). Bioreactors: How to study biofilms in vitro. In A. C. Ionescu & S. Hahnel (Eds.), Oral biofilms and modern dental materials: Advances toward bioactivity (1st ed., p. 41). Springer Nature.
Ochoa, R., Martínez-Pabón, M. C., Arismendi-Echeverri, M. A., Rendón-Osorio, W. L., & Muskus-López, C. E. (2017). In silico search of inhibitors of Streptococcus mutans for the control of dental plaque. Archives of Oral Biology, 83, 68–75.
Robinson, D. B. T., Hopkins, L., Brown, C., Abdelrahman, T., Powell, A. G., Egan, R. J., et al. (2019). Relative value of adapted novel bibliometrics in evaluating surgical academic impact and reach. World Journal of Surgery, 43(4), 967–972.
Egghe, L. (2006). Theory and practice of the g-index. Scientometrics, 69(1), 131–152.
Hirsch, J. E. (2005). An index to quantify an individual’s scientific research output. Proceedings of the National Academy of Sciences, 102(46), 16569–16572.
Kuhn, T. S. (1962). Historical structure of scientific discovery. Science, 136(3518), 760–764.
Huo, Y., Pan, X., Li, Q., Wang, X., Jiao, X., Jia, Z., et al. (2015). Fifty top-cited classic papers in orthopedic elbow surgery: A bibliometric analysis. International Journal of Surgery, 18, 28–33.
Alvarado, R. U. (2016). Growth of literature on Bradford’s law. Investigación Bibliotecológica, 30(68), 51–72.
Aytaç, S., Tran, C. Y., & Frye, N. (2025). Lotka’s law of scientific productivity across the research disciplines: A review. Science & Technology Libraries.
Van Eck, N. J., & Waltman, L. (2010). Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics, 84(2), 523–538.
Verma, S., & Sharma, H. (2024). Quantity over quality of publications: Are we using the right metrics to judge author’s productivity and impact in biomedical research? Journal of Postgraduate Medicine, 70(3), 154–161.
Põder, E. (2022). What is wrong with the current evaluative bibliometrics? Frontiers in Research Metrics and Analytics, 6, 824518.

Details

Primary Language

English

Subjects

Restorative Dentistry

Journal Section

Research Article

Authors

Merve Yıldırım Üçüncü
0000-0001-8136-230X
Türkiye

Musa Kazım Üçüncü ^*
0000-0002-2352-8532
Türkiye

Publication Date

April 30, 2026

Submission Date

February 16, 2026

Acceptance Date

April 1, 2026

Published in Issue

Year 2026 Volume: 4 Number: 1

DOI

https://doi.org/10.62243/edr.1891019

IZ

https://izlik.org/JA32ML57NL

Cite

RIS / Bibtex

APA

Yıldırım Üçüncü, M., & Üçüncü, M. K. (2026). The Global Knowledge Architecture of Streptococcus mutans: A Bibliometric Analysis. Eurasian Dental Research, 4(1), 13-20. https://doi.org/10.62243/edr.1891019

AMA

1.Yıldırım Üçüncü M, Üçüncü MK. The Global Knowledge Architecture of Streptococcus mutans: A Bibliometric Analysis. EDR. 2026;4(1):13-20. doi:10.62243/edr.1891019

Chicago

Yıldırım Üçüncü, Merve, and Musa Kazım Üçüncü. 2026. “The Global Knowledge Architecture of Streptococcus Mutans: A Bibliometric Analysis”. Eurasian Dental Research 4 (1): 13-20. https://doi.org/10.62243/edr.1891019.

EndNote

Yıldırım Üçüncü M, Üçüncü MK (April 1, 2026) The Global Knowledge Architecture of Streptococcus mutans: A Bibliometric Analysis. Eurasian Dental Research 4 1 13–20.

IEEE

[1]M. Yıldırım Üçüncü and M. K. Üçüncü, “The Global Knowledge Architecture of Streptococcus mutans: A Bibliometric Analysis”, EDR, vol. 4, no. 1, pp. 13–20, Apr. 2026, doi: 10.62243/edr.1891019.

ISNAD

Yıldırım Üçüncü, Merve - Üçüncü, Musa Kazım. “The Global Knowledge Architecture of Streptococcus Mutans: A Bibliometric Analysis”. Eurasian Dental Research 4/1 (April 1, 2026): 13-20. https://doi.org/10.62243/edr.1891019.

JAMA

1.Yıldırım Üçüncü M, Üçüncü MK. The Global Knowledge Architecture of Streptococcus mutans: A Bibliometric Analysis. EDR. 2026;4:13–20.

MLA

Yıldırım Üçüncü, Merve, and Musa Kazım Üçüncü. “The Global Knowledge Architecture of Streptococcus Mutans: A Bibliometric Analysis”. Eurasian Dental Research, vol. 4, no. 1, Apr. 2026, pp. 13-20, doi:10.62243/edr.1891019.

Vancouver

1.Merve Yıldırım Üçüncü, Musa Kazım Üçüncü. The Global Knowledge Architecture of Streptococcus mutans: A Bibliometric Analysis. EDR. 2026 Apr. 1;4(1):13-20. doi:10.62243/edr.1891019